Pharmaceutical composition for treating primary trigeminal neuralgia

A technology for trigeminal neuralgia and composition, applied in the field of traditional Chinese medicine, can solve problems such as damage to cranial nerve or brain tissue, high treatment cost, leukopenia, etc., and achieve the effects of relieving the disease, promoting the smooth flow of qi and blood, and formulating strict prescriptions

Inactive Publication Date: 2016-07-27
陈红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Not only the treatment time is long, but the treatment cost is also relatively high; some may even cause damage to cranial nerves or brain tissue, and there are also serious sequelae such as blindness, cerebral hemorrhage, and facial paralysis.
The side effects of western medicine are relatively obvious. Some patients have dizziness, fatigue, nausea and vomiting, leukopenia, rash and other adverse reactions after use.

Method used

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  • Pharmaceutical composition for treating primary trigeminal neuralgia
  • Pharmaceutical composition for treating primary trigeminal neuralgia

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1 capsule

[0039] Prescription: 12 parts of Rhizoma Chuanxiong, 15 parts of Red Hair Seven, 10 parts of Moutan Cortex, 5 parts of Hexuexiang, 10 parts of Rose, 10 parts of Euonymus, 20 parts of Palm Ginseng, 8 parts of Fangfeng, 9 parts of Tianma, loofah 6 servings.

[0040] Preparation method: take Rhizoma Chuanxiong, Rhododendron chinensis, Cortex Moutan, and Hexuexiang, add 3 to 7 times the weight of medicinal materials, and ethanol with a concentration of 70%, heat and reflux for extraction twice, each time for 1.0 to 1.5 hours, filter, and recover the filtrate Ethanol is concentrated into a thick paste, dried, crushed into a dry paste powder, and set aside;

[0041] Take rose, euonymus, palm ginseng, windproof, gastrodia elata, loofah together with Chuanxiong, Hongmaoqi, moutan cortex, Hexuexiang ethanol to extract the dregs, add 6 to 10 times the weight of the medicinal materials in water, decoct and extract 2 times, filter, concentrate the filtrate ...

Embodiment 2

[0042] Embodiment 2 capsules

[0043] Prescription: 10 parts of Rhizoma Chuanxiong, 12 parts of Hongmaoqi, 10 parts of Moutan Bark, 6 parts of Hexuexiang, 12 parts of Rose, 12 parts of Euonymus, 18 parts of Palm Ginseng, 8 parts of Fangfeng, 9 parts of Gastrodia elata, loofah 6 servings.

[0044] Preparation method: refer to the operation of Example 1.

Embodiment 3

[0045] Embodiment 3 capsules

[0046] Prescription: 10 parts of Rhizoma Chuanxiong, 12 parts of Hongmaoqi, 12 parts of Moutan Cortex, 4 parts of Hexuexiang, 10 parts of Rose, 15 parts of Euonymus, 15 parts of Palm Ginseng, 6 parts of Fangfeng, 8 parts of Gastrodia elata, loofah 6 servings.

[0047] Preparation method: refer to the operation of Example 1.

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PUM

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Abstract

The invention discloses a pharmaceutical composition for treating primary trigeminal neuralgia and a preparation method thereof. The pharmaceutical composition consists of an oral-administration medicine and an external-application medicine, wherein the oral-administration medicine is prepared from the following raw materials: ligusticum wallichii, radix caulophylli, cortex moutan, lysimachia sikokiana, rose, euonymus myrianthus, rhizoma gymnadeniae, radix saposhnikoviae, rhizoma gastrodiae and loofah sponge; the external-application medicine is mainly prepared from the following raw materials: radix angelicae, garden balsam stem, parthenocissus tricuspidata and fructus kochiae. Through external application, the blocked blood vessels and meridians and collaterals of a patient are dredged, smooth qi and blood are promoted, and the illness state is relieved; the Zang-Fu functions are regulated by the oral administration of the medicine; by combining external application and oral administration, internal and external treatment is realized, and a satisfactory clinical treatment effect is easier to obtain on the whole. Meanwhile, the pharmaceutical composition causes few side effects, can effectively relieve the burden and pain of the patient and deserves clinical wide promotion and application.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and relates to a pharmaceutical composition for treating primary trigeminal neuralgia and a preparation method thereof. Background technique [0002] Primary trigeminal neuralgia (trigeminal neuralgia, TN) refers to recurrent paroxysmal, short-term, severe pain in the distribution area of ​​the trigeminal nerve without symptoms of trigeminal nerve dysfunction. It occurs mostly in middle-aged and elderly people over 40 years old, and women are slightly more than men. The clinical manifestations are electric shock-like and tear-like pain in the distribution area of ​​the trigeminal nerve, which is paroxysmal, usually lasts for a few seconds or 1-2 minutes, and the pain is sudden and severe. The pain is usually unilateral, but a few are bilateral. The disease recurs and rarely recovers spontaneously. At present, the etiology and pathogenesis of TN are not very clear. In recen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8988A61K36/87A61P25/02A61P29/00
CPCA61K36/236A61K9/0014A61K9/0053A61K36/185A61K36/232A61K36/238A61K36/29A61K36/37A61K36/42A61K36/47A61K36/65A61K36/71A61K36/738A61K36/87A61K36/898A61K36/8988A61K2236/331A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 陈红
Owner 陈红
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