Aerosol precursor containing medicinal compositions of snake gall and unibract fritillary bulb powder and method for dispersing aerosol precursor into nano-scale fog droplets

A technology of Shedan Chuanbei powder and effective ingredients, which is applied in the field of aerosol precursors, can solve the problems of demanding airtightness of propellant storage tanks, poor drug atomization effect, and high cost of propellants, achieving Good medicinal value, reducing sweetness and shortening the effect of time

Inactive Publication Date: 2015-05-27
CHINA TOBACCO YUNNAN IND
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0005] The representative patent for pressurized atomization of traditional Chinese medicine compound preparations is CN102949573A, in which an 80-100bar propellant such as trichlorofluoromethane, dichlorodifluoromethane or dichlorotetrafluoroethane is used to atomize the liquid medicine to To obtain micron-sized mist droplets, the above-mentioned injection pressure is too high, the airtightness of the propellant container tank is strict, the production cost is high, and the propellant itself is also expensive
In addition, with the increase of the amount of medicine used, the pressure inside the tank decreases continuously, and the drug atomization effect gradually becomes worse; moreover, such tanks can only be used once for consumers, increasing usage cost

Method used

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Embodiment 1

[0030] An aerosol precursor comprising Shedan Chuanbei Powder medicinal ingredients, which comprises glycerol, propylene glycol, 1,3-butanediol, flavoring substances and Shedan Chuanbei Powder extract, the mass ratio of which is glycerol Alcohol: Propylene Glycol: Shedan Chuanbeisan Extract = 40:20:1.

[0031] Wherein said Shedan Chuanbeisan extract is obtained by a method comprising the following steps:

[0032] (1) Impurity removal: dissolve Shedan Chuanbei Powder in food-grade ethanol, filter, remove insoluble impurities, and obtain the ethanol solution of Shedan Chuanbei Powder;

[0033] (2) decolouring: the ethanol solution of Shedan Chuanbei powder obtained in step (1) is passed through the first macroporous resin chromatographic column, and is 40 volume % ethanol-water solution elution with concentration, removes the pigment component wherein, and utilizes Molecular distillation removes solvent to obtain the first extract; wherein the model of the first macroporous res...

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Abstract

The invention relates to an aerosol precursor containing medicinal compositions of snake gall and unibract fritillary bulb powder. The aerosol precursor comprises the following components: glycerol, propylene glycol, 1,3-butanediol, aromatic substances and a snake gall and unibract fritillary bulb powder extract, wherein a mass proportion of glycerol to propylene glycol to 1,3-butanediol to the aromatic substances to the snake gall and unibract fritillary bulb powder extract is equal to (40-45):(20-25) :(0-10) :(0-10) :(1-10). The invention also relates to a method for dispersing the medicinal compositions in the snake gall and unibract fritillary bulb powder into nano-scale fog droplets, and also relates to an aerosol containing the nano-scale fog droplets. The aerosol precursor disclosed by the invention contains the medicinal compositions of the snake gall and unibract fritillary bulb powder, and the nano-scale fog droplets can be obtained by heating the aerosol precursor in an electronic cigarette smoking set which comprises an electric heating device so as to ensure that the aerosol precursor can be more beneficial for a human body to absorb the medicinal compositions.

Description

technical field [0001] The invention relates to an aerosol precursor, in particular to an aerosol precursor containing medicinal ingredients of Shedan Chuanbei Powder and a method for dispersing it into nano-scale droplets. Background technique [0002] The main components of Shedan Chuanbei Powder are snake bile and Chuanbeimu. It is light yellow to light brown powder; sweet in taste, slightly bitter, has the effects of clearing lung, relieving cough and eliminating phlegm. Usually, the administration method of Shedan Chuanbei Powder is oral administration. On the one hand, the drug effect is slow; Drug utilization decreased. [0003] Aerosols generally refer to preparations that produce droplets when heated or pressurized. In the field of medicine and pharmacy, aerosols refer to preparations that contain medicinal liquids, emulsions or suspensions that are sprayed out in the form of mist for lung inhalation or directly sprayed to the mucous membranes of the cavity, skin...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K9/12A61K9/72A61P11/14A61P11/10A24B15/16A24B15/22A61K35/583
Inventor 杨继段沅杏韩敬美田永峰杨柳尚善斋赵伟袁大林秦云华陈永宽缪明明
Owner CHINA TOBACCO YUNNAN IND
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