Measurement method of local pulse wave velocity in carotid artery

Abstract

The method for measuring the local pulse wave propagation velocity of the carotid artery comprises the following steps: Step 1, designing an ultra-fast comb-tooth-shaped focused beam transmitting and receiving sequence, and simultaneously acquiring multi-point radio frequency echo signals along the long axis direction of the carotid artery; Step 2 1. After filtering and preprocessing the multiple focused beam echo signals received at the same time along the long axis of the carotid artery, identify and track the echo signals of the front and rear walls of the blood vessel in each scan line. Step 3: For each scan line The adjacent frame echo signals of the front and rear walls of the medium blood vessel are respectively estimated by one-dimensional autocorrelation phase shift to obtain the corresponding phase shift velocity waveform. After that, the phase shift waveform corresponding to the change of the blood vessel wall with the cardiac cycle at each scan line is obtained ; Step 4, calculating the relative time delay between adjacent scanning line blood vessel wall phase shift waveforms, carrying out linear fitting to the time delay, the reciprocal of its slope is the estimated local pulse wave propagation velocity; the present invention is atherosclerosis Provide a new basis for early detection.

Description

Technical field [0001] The present invention relates to the technical field of ultrasound imaging, in particular to a method for measuring the local pulse wave propagation velocity of a carotid artery based on an ultra-fast comb-shaped focused beam transmitting and receiving sequence. Background technique [0002] Arterial hypoelasticity is a comprehensive manifestation of early damage to the vascular wall by multiple factors, and is a better specific and sensitive indicator of early vascular disease. At present, clinically, only B-ultrasound images and Doppler blood flow can be used to diagnose vascular wall thickening or the presence of plaque in the stage of vascular structural disease. It is impossible to achieve quantitative early detection and evaluation of atherosclerosis in the stage of vascular disease. . In 1878, Moens et al. deduced the mathematical equation of pulse wave velocity (PWV) and elastic modulus, namely the Moens-Korteweg equation, which confirmed that the ...

AI Technical Summary

Problems solved by technology

However, the traditional B-ultrasound imaging mode is realized by sequentially focusing on transmitting and receiving scan lines one by one. The imaging frame rate of this imaging mode is only tens of hertz, while the human pulse wave propagation speed can reach several meters per second. The frame rate of traditional ultrasound imaging It is difficult to capture the propagation of pulse waves on local vessel segments

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