Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Application of alantolactone in preparation of medicines for resisting cryptosporidium parvum

A technology of Cryptosporidium parvum and inulin, applied in application, anti-infective drugs, drug combination, etc.

Active Publication Date: 2015-06-03
INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
View PDF1 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] So far, there is no report that inulin has anti-Cryptosporidium parvum, and it is impossible to infer whether it has anti-Cryptosporidium parvum based on the known properties of inulin.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Application of alantolactone in preparation of medicines for resisting cryptosporidium parvum

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] Preparation of inulin powder: take 3.8g of inulin (content not less than 98%) and 96.2g of starch and mix well. Inulin was purchased from Shanghai Chunyou Biotechnology Co., Ltd., item number: P0182.

[0013] The usage and dosage of the powder: mix the above 100g powder into 100 kg of feed, and feed according to the daily food intake.

Embodiment 2

[0015] Preparation of inulin water-soluble powder: take 1.9 g of inulin (content not less than 98%) and 98.1 g of glucose and mix well.

[0016] Dosage of water-soluble powder: Dissolve 100g of the above-mentioned powder in 100 liters of water, and feed according to the normal amount of drinking water.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses an application of alantolactone in preparation of medicines for resisting cryptosporidium parvum. The application method comprises the following steps: preparing powder from alantolactone and acceptable auxiliary materials; adding to a feed, mixing evenly, and feeding mouse according to the daily feed amount; or preparing an alantolactone water-soluble power from the alantolactone, dissolving into water, and feeding the mouse according to the daily water consumption. An animal infection experiment proves that the oocysts after cryptosporidium parvum injection can be reduced by 75% or above by the alantolactone; and the alantolactone has a relatively good effect of resisting cryptosporidium parvum.

Description

technical field [0001] The invention relates to a new application of a compound, in particular to the application of inulin in the preparation of anti-Cryptosporidium parvum drugs. Background technique [0002] Cryptosporidium parvum ( Cryptosporidium parvum ) is one of the zoonotic parasites that cause severe watery diarrhea in humans and animals. It is distributed worldwide, and the cryptosporidiosis caused by it has been included in the six most common diarrheal diseases in the world. It is a great life threat to infants and immunocompromised patients. [0003] The main source of infection for cryptosporidiosis is feces and vomit excreted by humans or animals containing a large number of oocysts, and the oocyst excretion cycle can last from several days to several weeks. Oocysts are brought into domestic water sources through discharge of domestic sewage and surface runoff of precipitation, making Cryptosporidium an important waterborne pathogen. Cryptosporidium parvu...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/365A61P33/02A23K1/16
CPCY02A50/30
Inventor 李娟孙铭飞林栩慧戚南山廖申权吴彩艳吕敏娜
Owner INST OF ANIMAL HEALTH GUANGDONG ACADEMY OF AGRI SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com