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Drug for treating traumatic arthritis caused by deficiencies in liver and kidney and preparation method thereof

A traumatic technology for liver and kidney deficiency, applied in the field of pharmacy, can solve problems such as inappropriate use of anti-inflammatory painkillers, risks in surgical treatment, pain of rehabilitation patients, etc., achieve remarkable curative effect, convenient administration, and control the development of the disease

Inactive Publication Date: 2015-07-15
JINAN HONGFEI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, Western medicine has many side effects. Anti-inflammatory and analgesic drugs are palliative drugs, mainly to relieve pain symptoms. For patients with high-risk factors, such as heart, kidney, and liver insufficiency, anti-inflammatory and analgesic drugs with high-risk side effects should not be used. There are risks in the treatment, and postoperative rehabilitation also brings great pain to the patient

Method used

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Effect test

preparation example Construction

[0072] In order to solve the above-mentioned technical problems, the present invention also provides a preparation method of a pharmaceutical preparation for treating liver and kidney deficiency type traumatic arthritis. When the dosage form of the medicine is granules, the preparation method comprises the following steps:

[0073] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% that is 4 to 8 times that of the mixture, heat to boiling and reflux for 3 to 5 hours, filter, and use the percolation method to obtain Slowly percolate at a speed of 1-2ml per minute, collect the percolation liquid, then concentrate under reduced pressure at a vacuum of 0.06-0.09Mpa to a paste with a relative density of 1.04-1.10 at 50-60°C, spray dry, spray dry The air inlet temperature of the machine is 160-175°C, the outlet air temperature is 80-85°C, and then crushed into powder to make dry cream powder; Step 2: Add 0.2-...

Embodiment 1

[0087] Embodiment 1 Granules of the present invention

[0088] The embodiment of the present invention provides a medicine for treating traumatic arthritis of liver and kidney deficiency type, which is prepared from the following raw materials: Cassia chinensis 31g, Corydalis Corydalis 27g, Shayuanzi 12g, Dogji 25g, Rehmannia glutinosa 32g, 7g heather leaves, 20g white peony root, 10g holly seeds, 18g medlar root, 28g citrus aurantium, 22g sagittarius vine, 12g whipped hydrangea, 23g woody fragrance, 18g black medicine, 9g nine-scented insect, 17g euphemum, 11g verbena , Jiangxiang 22g, red cohosh 8g, Dapaotong 18g, Sangjisheng 28g, Wujiapi 12g, Qiannianjian 13g and licorice 20g.

[0089] Its preparation method comprises the following steps:

[0090] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 6 times that of the mixture and 90% ethanol, heat to boiling and reflux for 4 hours, filter, and slow down the mixtu...

Embodiment 2

[0091] Embodiment 2 Capsules of the present invention

[0092] The embodiment of the present invention provides a medicine for treating traumatic arthritis of liver and kidney deficiency type, which is prepared from the following raw materials: Cassia chinensis 30g, Rhizoma Corydalis 28g, Semen Shayuan 14g, Dogji 27g, Rehmannia glutinosa 30g, Heather leaves 8g, white peony root 25g, holly seeds 9g, medlar root 15g, citrus aurantium 30g, sage vine 25g, whipped hydrangea 10g, woody fragrance 19g, black medicine 22g, chrysanthemum worm 11g, euphemum 13g, verbena 15g , Jiangxiang 20g, red cohosh 10g, Dapaotong 15g, Sangjisheng 26g, Wujiapi 10g, Qiannianjian 11g and licorice 19g.

[0093] Its preparation method comprises the following steps:

[0094] In the first step, mix Cassia chinensis, Corydalis Corydalis, Shayuanzi, Gouji, Rehmannia glutinosa, heather leaves, white peony root, wintergreen seeds and wolfberry root according to the stated ratio, add 5 times the amount of water...

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Abstract

The invention discloses a drug for treating traumatic arthritis caused by deficiencies in the liver and kidney and a preparation method thereof. The drug comprises the following components: abalone shell, corydalis tuber, semen astragali complanati, cibotium rhizome, prepared rehmannia root, Chinese photinia leaf, white peony root, Chinese ilex seed, Ilex cornuta root, bitter orange, sargentgloryvine stem, hemiphragma heterophyllum, banksia rose, combined spicebush, aspongopus, herba lycopi, verbena, dalbergia odorifera, astilbe chinensis, root of delavay schefflera, taxillus chinensis, cortex acanthopanacis, homalomena occulta, and licorice. The drug is mainly used to treat traumatic arthritis caused by deficiencies in liver and kidney, has the functions of tonifying liver, boosting kidney, regulating qi, activating blood, strengthening the muscles and bones, boosting qi, relieving pains, freeing collaterals, and removing stasis, can effectively prevent the disease from degrading and relieve the pains for patients, is capable of treating the disease effectively and acting on the lesions directly, and has the advantages of simple manufacturing technology, prominent effect, short treatment course, low cost, safety, effectiveness, user-friendliness, and easy acceptance.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a medicine for treating traumatic arthritis of liver and kidney deficiency type and a preparation method thereof. Background technique [0002] Traumatic arthritis, also known as traumatic arthritis and traumatic osteoarthritis, is a secondary preventable osteoarthritis caused by trauma with degeneration of articular cartilage and secondary cartilage hyperplasia and ossification As the main pathological changes, it is a disease with joint pain and activity dysfunction as the main clinical manifestations. Traumatic arthritis can occur in any age group, but it is more common in young adults who are fond of sports, and the knees, ankles, hips, fingers (toes) and other joints are most commonly affected. Traumatic arthritis can be complicated by bone collapse and subchondral sclerosis. In the late stage, the medial joint space of the knee disappears, the knee joint is subluxed due...

Claims

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Application Information

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IPC IPC(8): A61K36/888A61P19/02A61K35/618A61K35/64
Inventor 毕旻生
Owner JINAN HONGFEI BIOTECH
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