Unlock instant, AI-driven research and patent intelligence for your innovation.

Encoded polymer microparticles

A polymer particle, polymer technology, applied in the field of encoded polymer particles, which can solve the problems of vulnerability, analytical error, poor physical/chemical durability, etc.

Active Publication Date: 2015-07-15
昆塔麦特利斯株式会社
View PDF7 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, encoded polymeric microparticles may be easily damaged due to the poor physical / chemical durability of the polymeric material constituents and may absorb analytes, causing analytical errors
In addition, bioconjugation of polymer particles to biomaterials is limited to a few specific chemistries and cannot accommodate different conjugation chemistries.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Encoded polymer microparticles
  • Encoded polymer microparticles
  • Encoded polymer microparticles

Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0016] Embodiments of the present invention will now be described in more detail with reference to the accompanying drawings. These embodiments are provided so that the present invention will fully convey the scope of the present invention to those skilled in the art. Thus, the present invention may be embodied in many different forms and should not be construed as limited to the exemplary embodiments set forth herein. In the drawings, dimensions such as width, length and thickness of elements may be exaggerated for clarity. It will be understood that when an element is referred to as being "on" another element, it can be directly on the other element or one or more intervening elements may also be present.

[0017] figure 1 Encoded polymer microparticles according to one embodiment of the invention are shown. exist figure 1 , lower views of A, B, and C show cross-sections taken along lines A-A', B-B', and C-C', respectively. refer to figure 1 Part A of the coded polymer...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
thicknessaaaaaaaaaa
Login to View More

Abstract

Provided are encoded polymeric microparticles and a multiplexed bioassay using the encoded polymeric microparticles. Each of the encoded polymeric microparticles includes an encoded polymeric microparticle core and a silica shell surrounding the microparticle core. Further provided is a method for producing encoded polymeric microparticles. The method includes: mixing a photocurable material with a linker having a functional group polymerizable with the photocurable material and an alkoxysilyl group; applying patterned energy to cure the mixture, followed by encoding to obtain encoded polymeric microparticle cores; and treating the encoded polymeric microparticle cores with a silica precursor to form a silica shell on each encoded polymeric microparticle core.

Description

technical field [0001] The present invention relates to encoded polymer particles. More specifically, the present disclosure relates to encoded polymer microparticles that have excellent chemical and physical stability and can be mass-produced, methods for producing the encoded polymer microparticles, and multiple organisms using the encoded polymer microparticles. Assay (multiplexed bioassay). Background technique [0002] Recently, encoded polymer particles have been widely used to detect biological analytes (eg, DNA or proteins) due to their facile fabrication process and large encoding capacity. However, encoded polymeric microparticles may be easily damaged due to poor physical / chemical durability of the polymeric material constituents and may absorb analytes, causing analytical errors. In addition, bioconjugation of polymer particles to biomaterials is limited to a few specific chemistries and cannot accommodate different conjugation chemistries. Therefore, there is...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C08J7/06G01N33/50C12Q1/68
CPCC12Q1/6825C12Q1/708G01N33/50G01N33/56916C08J7/06G01N33/552G01N33/54313G01N33/531G01N33/5434
Inventor 权圣勋金美罗张志诚裵亨钟金娜悧
Owner 昆塔麦特利斯株式会社