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Application of Natamycin in Killing Cucumberia and Stimulating Cryptocaryonia

A technique for stimulating Cryptocaryonia, natamycin, applied in the application of killing and stimulating Cryptocaryonia, in the field of natamycin, it can solve the problem of Cryptocaryonia and stimulate Cryptocaryon without significant effect, Drug residues, environmental pollution and other problems, to achieve significant killing effect, less residue, good dissolution effect

Active Publication Date: 2017-08-04
ZHEJIANG INST OF FRESH WATER FISHERIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The most effective drugs to treat these two parasites are mercurous nitrate and malachite green, and these two drugs have carcinogenic effects, so they have been banned
With the prohibition of these two drugs, formaldehyde, copper sulfate, potassium permanganate, bronopol, etc. are mainly used for the prevention and treatment of these two parasites at home and abroad at present, but these drugs have no effect on the small melon worm and Cryptocaryon irritant. Significant curative effect, while long-term use has brought problems such as drug residues, environmental pollution, drug resistance, etc., so there is an urgent need for drugs with specific effects on these two parasites

Method used

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  • Application of Natamycin in Killing Cucumberia and Stimulating Cryptocaryonia
  • Application of Natamycin in Killing Cucumberia and Stimulating Cryptocaryonia
  • Application of Natamycin in Killing Cucumberia and Stimulating Cryptocaryonia

Examples

Experimental program
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Effect test

Embodiment 1

[0026] Weigh 5g of natamycin, stir and dissolve in 10g of dimethyl sulfoxide, weigh 5g of surfactant Tween-20, and 80g of solvent water, mix and stir evenly to obtain the control agent.

Embodiment 2

[0028] Weigh 10g of natamycin, stir and dissolve in 20g of glacial acetic acid, weigh 10g of surfactant Tween-20, and 60g of solvent water, mix and stir evenly to obtain the control agent.

Embodiment 3

[0030] Weigh 15g of natamycin, stir and dissolve in 20g of N,N-dimethylformamide, weigh 10g of surfactant Tween-80, and 55g of solvent water, mix and stir evenly to obtain the control agent.

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Abstract

The invention belongs to the technical field of application of chemical products, and discloses a control agent for killing small melon worms and Cryptocaryon irritant in vitro of aquatic animals, which comprises the following raw materials in percentage by weight: natamycin 5%-25%, surfactant 5%~10%, dissolving agent 10~20%, the rest is solvent, the sum of the above raw materials is 100%. The present invention adopts natamycin, which has low toxicity, is non-toxic to aquatic animals, and has little residue; using a specific dissolving agent and solvent, the dissolving effect is good, and the dissolving agent can assist the control agent to enter the body of the small melon worm, so as to kill the small melon worm. The control agent is easy to prepare, convenient to use and low in production cost.

Description

[0001] Application of natamycin in killing melon worm and stimulating Cryptocaryonia. technical field [0002] The invention belongs to the technical field of application of chemical products, and specifically relates to the application of natamycin in killing melon worms and stimulating Cryptocaryonia. [0003] technical background [0004] Natamycin (Natamycin) is a natural antifungal compound produced by Streptomyces fermentation. It belongs to polyene macrolides. It can be widely used in food preservation and antifungal treatment. Its structural formula is: [0005] [0006] Natamycin, the molecular formula is C 33 h 47 NO 13 , Light yellow or light brown powder, melting point is 280°C, slightly soluble in water, hardly soluble in most organic solvents. It relies on its lactone ring structure to interact with sterol compounds on the fungal cell membrane to form antibiotic-sterol compounds, thereby destroying the structure of the fungal cytoplasmic membrane. The h...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/7048A61P33/14
Inventor 姚嘉赟沈锦玉尹文林袁雪梅蔺凌云徐洋潘晓艺郝贵杰
Owner ZHEJIANG INST OF FRESH WATER FISHERIES
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