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Medicine for treating fracture of femoral shaft and preparation method thereof

A femoral backbone and drug technology, applied in the field of pharmaceutical preparations, can solve the problems of long treatment time, insufficient blood supply to the broken end, premature weight-bearing, etc., and achieve the effects of no toxic and side effects, short treatment course and high efficiency.

Inactive Publication Date: 2015-07-29
赵振荣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

4. Contact of the fracture surface: due to poor restoration or improper fixation, the fracture ends are still angled, displaced, and separated, which are likely to cause fracture nonunion or delayed union
6. Premature weight bearing: unreasonable early movement, tearing the newly formed fibrous callus or bony callus, resulting in fracture nonunion or delayed union
7. Insufficient blood supply to the stump: tissue regeneration requires sufficient blood supply
Although western medicine can reset the bone setting in time, the curative effect is not good after the operation, the treatment time is long, the bone healing is slow, the patient's physical strength is not easy to recover, and factors such as long-term bed rest lead to complications. play an irreplaceable role

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0072] When the dosage form of the medicine is a tablet, its preparation method may further comprise the steps:

[0073] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixture, heat and reflux for 4 to 6 hours, extract, and filter to obtain the first extraction liquid; the medicinal dregs obtained by filtering are then added with ethanol with an alcohol concentration of 90% to 95% relative to the quality of the medicinal dregs 2 to 4 times, heated and refluxed for 1 to 3 hours, extracted, and filtered to obtain a second extract; The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0074] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 3 hours, pulverized, and sieved to obtain an ultrafine powder of 400 mesh to 5...

Embodiment 1

[0080] Example 1 Patches

[0081] The preparation process of the patch of the present invention is as follows: take 200g of Angelica sinensis, 350g of Dabagu, 150g of Radix Paeoniae Rubra, 420g of Feilongzhangxue, 200g of Rehmannia glutinosa, 330g of small red ginseng, 220g of Rhizoma Drynariae, 140g of thistle, 350g of natural copper, 160g of frankincense, 440g of Digupi, 200g of myrrh, 300g of elderberry, 400g of sumac, 230g of jiu dao sheng, 150g of Caulis Spatholobus, 300g of roasted astragalus, 220g of madder, 180g of Eucommia, 420g of trigonum, 170g of dodder, 250g of dragon boat flower , 140g catechu, 350g seabuckthorn, 20g Duyiwei, 250g knotweed, 420g pig marrow and 330g Echinococcus japonicus;

[0082] In the first step, mix Myrrha, Elderberry, Sappanwood, Jiu Dao Sheng, Millet Spatholobus, Radix Astragalus, Rubia, Eucommia and Sanleng according to the stated ratio, and use an alcohol concentration that is 4 times the mass of the obtained mixture Dissolve in 85% etha...

Embodiment 2

[0086] Example 2 tablet

[0087] The production process of the tablet of the present invention is as follows: take 300g of Angelica sinensis, 250g of Dabugu, 150g of Radix Paeoniae Rubra, 420g of Feilongzhangxue, 120g of Rehmannia glutinosa, 330g of small red ginseng, 250g of Rhizoma Drynariae, 140g of large thistle, 310g of natural copper, frankincense 200g, Digupi 440g, Myrrh 140g, Elderberry 300g, Sumac 410g, Jiu Dao Sheng 320g, Milletah 210g, Radix Astragali 300g, Rubia 220g, Eucommia 140g, Trigonum 420g, Cuscuta 150g, Dragon Boat Flower 300g, 120g catechu and 250g seabuckthorn;

[0088] The first step is to mix the raw materials of the drug in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 5 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 90% relative to the quality of the dregs, heat and reflux for 2 hours, extrac...

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PUM

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Abstract

The invention discloses a medicine for treating fracture of the femoral shaft and a preparation method thereof. The medicine comprises the following raw medicinal materials: Chinese angelica, adhatoda ventricosa, root of common peony, asiatic toddalia root, dried rehamnnia root, rubia yunnanensis, rhizoma drynariae, circium japonicum, native copper, olibanum, cortex lycii radicis, myrrh, elderberry, hematoxylon, asplenium varians wall., caulis spatholobi, radix astragali preparata, madder, eucommia ulmoides, rhizoma sparganii, the seed of Chinese dodder, ixora chinensis, cutch, lamiophlomis rotata, giant knot weed, pig marrow, fir club moss and sea-buckthorn. The medicine for treating the fracture of the femoral shaft has the beneficial effects that the medicine has the effects of invigorating blood and generating new blood, setting broken bones and connecting tendons, promoting circulation and removing stasis, and replenishing essence and generating marrow; the medicine is mainly used for treating the femoral fracture in the middle period after the operation; the medicine has the advantages of rapid effect, high efficiency, accurate curative effect, short course of treatment, zero toxic side effect, low cost, and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a medicine for treating femoral shaft fractures and a preparation method thereof. Background technique [0002] The femur is the longest tubular bone in the human body. The femoral shaft includes the diaphysis from 2-5 cm below the trochanter to 2-5 cm above the femoral condyle. The femoral shaft is surrounded by three groups of muscles. Due to the well-developed muscles of the thigh, there are often dislocations and overlaps after fractures. The distal end of the fracture often has a tendency to move inward, and the fracture that has been aligned often has a tendency to bulge outward. This kind of displacement and angulation tendency should be corrected and prevented during fracture treatment. When the lower third of the femur is fractured, because the blood vessels are located behind the femoral fracture, and the distal end of the fracture is often angl...

Claims

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Application Information

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IPC IPC(8): A61K36/902A61P19/08A61K33/26
Inventor 刘祥锋赵振荣
Owner 赵振荣
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