Ganoderan tripeptide filer system device and process

Abstract

The invention discloses a ganoderan tripeptide filer system device and process, wherein the device comprises a conveying pump, a stock solution tank, a stop valve, a control valve, a high pressure pump, a pressure generator, a four-way diverter valve, a serial pipe, a four-way diverter valve II, a diverter pipe, an ultrahigh pressure reaction tank, a polysaccharide peptide storage, a degradation reactor, a backflow degreaser, a vacuum pump, a Beta-reactor, a protein separator, an ion separator, an ion pump, a homogenizing purifier, a flow guide pipe, a backflow pipe and the like; the ganoderan tripeptide filer system device and process are characterized in that the high pressure pump and the pressure generator are in threaded connection with one end of the backflow degreaser by the backflow pipe; the other end of the backflow degreaser is in threaded connection with a threaded dual-head connector of the high pressure reaction tank by the flow guide pipe; pressure higher than that of a supercritical fluid extraction method is adopted, and ultrahigh pressure is utilized to substitute temperature match of supercritical fluid, so that a part of effective substance is prevented from being damaged by high temperature, and the ganoderan tripeptide filer system device and process belong to a purely physical extraction process and device; the temperature does not exceed 20 DEG C when ultrahigh pressure is 600Mpa, and the purification degree of the process at low temperature is far higher than that of the supercritical fluid extraction method, and the device is an innovated process device for producing a ganoderan tripeptide injection.

Description

technical field [0001] The invention relates to the synchronous integration of filtration, separation, extraction and purification processes, in particular to a Ganoderma lucidum polysaccharide tripeptide separation and filtration system device process, which belongs to the field of bioengineering applications. Background technique [0002] Ganoderma lucidum polysaccharide has the ability to resist oxygen free radicals, can inhibit the generation of O2- free radicals, has a scavenging effect on OH-, can significantly inhibit the peroxidation of red blood cell lipids, has SOD enzyme-like activity, and can scavenge superoxide free radicals. Protecting cells from damage by superoxide free radicals is one of its main functions. The process of submerged fermentation of ganoderma lucidum glycopeptides is complex and the yield is low, especially the removal of protein during the sugar preparation process is currently a difficult point in the separation and purification of polysacc...

AI Technical Summary

Problems solved by technology

[0002] Ganoderma lucidum polysaccharide has the ability to resist oxygen free radicals, can inhibit the generation of O2- free radicals, has a scavenging effect on OH-, can significantly inhibit the peroxidation of red blood cell lipids, has SOD enzyme-like activity, and can scavenge superoxide free radicals. Protecting cells from damage by superoxide free radicals is one of its main functions. The process of submerged fermentation of ganoderma lucidum glycopeptides is complex and the yield is low, especially the removal of protein during the sugar preparation process is currently a difficult point in the separation and purification of polysaccharides , the Sevag method needs to consume a large amount of organic solvents, and the operation is cumbersome; the boiling point of trifluorotrichloroethane is low (bp56 °C) and is volatile, so it should not be used in large quantities; although trichloroacetic acid can cause the degradation of polysaccharides, it affects its physiological activity. Enzymes are expensive and not suitable for industrial production, but the use of polysaccharide tripeptide separation and filtration system technology and equipment is a purely physical method to remove proteins. Using natural clarifiers for liquid broken Ganoderma lucidum spores can simplify the extraction process and improve the purity of polysaccharides. Decolorization is also a difficult problem in the process of polysaccharide extraction and purification. Activated carbon will absorb polysaccharides and cause loss of polysaccharides; H2O2 oxidative decolorization can easily cause some polysaccharides to degrade

[0003] With the rapid development of my country's economy, the continuous improvement of people's living standards and changes in dietary structure and lifestyle, the incidence of diseases caused by lifestyle such as (diabetes, cardiovascular disease, obesity, colon cancer, constipation, etc.) is increasing year by year High trend, the current treatment effect of diabetes and its complications is still not ideal, so the development of drugs and health food of Ganoderma lucidum polysaccharide peptide is one of the important measures to prevent and improve diabetes and delay the occurrence of complications, and its production process conditions must be improved

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