Preparation method of compound micro-ecological preparation effervescent tablets for preventing and treating fowl plague

A technology of compound microecology and effervescent tablets, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, antiviral agents, etc., can solve the problems of large residues, unsatisfactory effects, and large toxic and side effects, and achieve easy raw materials. Obtain, improve the body's immunity, and have less side effects

CN104873924AInactive Publication Date: 2015-09-02XINCHANG DACHENG BIOLOGICAL SCI & TECH
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2015-09-02
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a preparation method of compound micro-ecological preparation effervescent tablets for preventing and treating fowl plague, and belongs to the technical field of veterinary medicines. The preparation method comprises the following steps: preparing lactic acid bacterium freeze-dried powder; preparing traditional Chinese medicine polysaccharides and traditional Chinese medicine flavonoids; preparing mixed preparation freeze-dried powder; and uniformly mixing the mixed preparation freeze-dried powder with effervescent materials, compressing into tablets by using a tabletting machine, and quantitatively sub-packaging to obtain the compound micro-ecological preparation effervescent tablets for preventing and treating fowl plague. The preparation method disclosed by the invention has the beneficial effects as follows: (1) the compound micro-ecological preparation effervescent tablets are simple and easily-available in raw material and low in cost; (2) the compound micro-ecological preparation effervescent tablets can be fed to chicken when the chicken drink water so as to ensure that the manpower and material resources can be reduced and the stress on chicken populations can be reduced; and (3) the compound micro-ecological preparation effervescent tablets are reasonable in compatibility, ensure that all traditional Chinese medicines have the effect of supplementing each other, are small in side effect, have the effects of diminishing inflammation, resisting virus and improving the body immunity, can be used for effectively preventing and treating fowl plague diseases, and ensure that the cure rate can reach more than 90%.
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Description

technical field

[0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to a preparation method of a compound microecological preparation effervescent tablet for preventing and treating fowl plague. Background technique

[0002] Fowl plague is a highly contagious disease that threatens the poultry industry as a major infectious disease, characterized by: acute, septic changes, parenchymal organ hemorrhage, necrosis and infarction; chronic fibrinous necrotic enteritis , Paratyphoid and pasteurellosis are often secondary in the later stage. The disease only infects chickens under natural conditions, and chickens and pheasants of different ages, sexes, and varieties are susceptible, and can occur throughout the year.

[0003] In the prior art, the commonly used chemical reagents for the treatment of fowl blast have unsatisfactory effects, large toxic and side effects, and large residues. In addition, in the prior art, there has ne...

Examples

Embodiment 1

[0023] Embodiment 1: the preparation of lactic acid bacteria freeze-dried powder

[0024] (1) Preheat the MRS liquid medium to 37°C, inoculate the lactic acid bacteria seed liquid at 5% inoculum, and culture it at 37°C for 18-24 hours, harvest the bacterial liquid and store it at -4°C for later use. The lactic acid bacteria for Lactobacillus Brucella ( Lactobacillus buchneri );

[0025] (2) Mix the lactic acid bacteria liquid and the freeze-drying protective agent (commercially available) at a volume ratio of 1:1, and freeze-dry in a vacuum to make the lactic acid bacteria freeze-dried powder.

Embodiment 2

[0026] Embodiment 2: the preparation of Chinese medicine polysaccharide and Chinese medicine flavone

[0027] (1) 20 parts by weight of lotus leaf, 2 parts by weight of comfrey, 10 parts by weight of Daqingye, 10 parts by weight of ginger, 30 parts by weight of woody fragrance, 30 parts by weight of red peony, 6 parts by weight of safflower and 6 parts by weight of almond Mix to obtain the mixed Chinese medicine;

[0028] (2) Take the mixed Chinese medicine, add purified water 20 times the weight of the raw materials, and boil in a water bath to 90°C for 4 hours;

[0029] (3) Discard the traditional Chinese medicine residue in step (2), collect the liquid medicine, centrifuge after cooling at room temperature, discard the precipitate, and collect the supernatant;

[0030] (4) The supernatant in step (3) is subjected to alcohol precipitation, the precipitate is the crude Chinese medicine polysaccharide, and the supernatant is the crude Chinese medicine flavonoid;

[0031] (5)...

Embodiment 3

[0035] Embodiment 3: the preparation of Chinese medicine polysaccharide and Chinese medicine flavone

[0036] (1) 10 parts by weight of lotus leaf, 10 parts by weight of comfrey, 5 parts by weight of Daqingye, 5 parts by weight of ginger, 20 parts by weight of woody fragrance, 20 parts by weight of red peony, 4 parts by weight of safflower and 4 parts by weight of almond Mix to obtain the mixed Chinese medicine;

[0037] (2) Take the mixed Chinese medicine, add purified water 20 times the weight of the raw materials, and boil in a water bath to 90°C for 4 hours;

[0038] (3) Discard the traditional Chinese medicine residue in step (2), collect the liquid medicine, centrifuge after cooling at room temperature, discard the precipitate, and collect the supernatant;

[0039] (4) The supernatant in step (3) is subjected to alcohol precipitation, the precipitate is the crude Chinese medicine polysaccharide, and the supernatant is the crude Chinese medicine flavonoid;

[0040] (5) ...