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Tildipirosin composition and applications thereof in treating or preventing poultry respiratory tract diseases

A technology of tediloxine and a composition, applied in the field of veterinary medicine, can solve the problems such as the application of tediloxine that has not yet been seen, and achieve the effects of broad market prospect and value, good therapeutic effect and long half-life

Active Publication Date: 2015-09-23
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] At present, Tedirosin has been approved by the FDA and EMEA for marketing. As a broad-spectrum antibacterial drug, it has antibacterial activity against some Gram-positive and Gram-negative bacteria. It is used to treat pigs and cattle and other animals infected by bacteria and mycoplasma. Respiratory diseases caused by the disease, but the application of Tedirosin in the treatment of poultry diseases has not been seen

Method used

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  • Tildipirosin composition and applications thereof in treating or preventing poultry respiratory tract diseases
  • Tildipirosin composition and applications thereof in treating or preventing poultry respiratory tract diseases
  • Tildipirosin composition and applications thereof in treating or preventing poultry respiratory tract diseases

Examples

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Comparison scheme
Effect test

Embodiment 1

[0033] The preparation of embodiment 1 tediroxin composition

preparation example 15

[0034] Preparation Example 15% (W / W) preparation of tedirosin composition soluble powder (calculated as tedirosin)

[0035] Take 65.33g of Tideroxin tartrate, 5.0g of houttuyfonate sodium, and 929.67g of sucrose powder, mix them uniformly step by step, pulverize them, and pass through an 80-mesh sieve to obtain the soluble powder of Tideroxin composition.

preparation example 21

[0036] Preparation Example 21% (W / W) Preparation of Tedirosin Composition Granules (calculated as Tedirosin)

[0037] Take 10 g of taiderocin, 10 g of houttuyfonate sodium, 3.07 g of tartaric acid, and 976.93 g of glucose powder, mix evenly, grind, and pass through an 80-mesh sieve to obtain taiderocin composition granules.

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Abstract

The invention discloses a tildipirosin composition and applications thereof in treating or preventing poultry respiratory tract diseases. The tildipirosin composition comprises tildipirosin / pharmaceutically-acceptable salts of tildipirosin, sodium houttuyfonate, and a pharmaceutically-acceptable carrier; and can be made into different oral dosage forms such as soluble powder, granule, oral liquid, premix, and the like. The provided tildipirosin composition has the characteristics of wide distribution in poultry body, large apparent volume of distribution, long half life, slow elimination, little using amount, and good curative effect, and has a good curative effect on poultry respiratory tract diseases caused by bacteria and mycoplasma.

Description

technical field [0001] The invention relates to a tedirosin composition and its application in treating or preventing poultry respiratory diseases caused by bacteria or mycoplasma, belonging to the field of veterinary medicine. Background technique [0002] With the expansion of the scale of intensive farming, the respiratory diseases, digestive system diseases and other diseases of livestock and poultry are becoming more and more serious. Taking poultry respiratory diseases as an example, the outbreak of respiratory diseases seriously affects poultry weight gain and feed utilization rate, resulting in lower egg production rate, lower quality of ketone body, and even a considerable number of deaths, which affects the economic benefits of poultry farming . Poultry respiratory diseases are more complicated in poultry production. There are many types of pathogens that cause diseases, including viruses, bacteria and mycoplasma, and the morbidity and mortality vary. The clinica...

Claims

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Application Information

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IPC IPC(8): A61K31/706A61P11/00A61P11/02A61P31/04A61P29/00A61K31/185
Inventor 张许科刘兴金周德刚
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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