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A method for wrapping volatile oil with low-temperature micropowder

A technology of volatile oil and micropowder, applied in the field of material processing, can solve problems such as low efficacy

Active Publication Date: 2018-07-06
ZHONGXING PHARM CO LTD JIANGSU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Using conventional mixing methods, although some active ingredients of volatile oil are temporarily retained in the raw and auxiliary materials during the mixing process, when the active ingredients of volatile oil pass through the process of making soft materials and granulating heating, the volatile oil almost completely disappears, resulting in drug effects. low

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0011] Embodiment 1 The method of wrapping the volatile oil in Shunqi Huatan Tablets with low-temperature fine powder.

[0012] Take the raw materials and auxiliary materials of Shunqi Huatan Tablets and pre-process them into soft materials according to conventional methods, such as preparing the raw materials and auxiliary materials of Shunqi Huatan Tablets into soft materials according to the method of patent CN201410765058. Under sealed conditions, the high-speed rotating turbine is used to pulverize to form fine powder. During the crushing process, the fine powder is repeatedly squeezed by the high-speed rotating turbine to generate a certain amount of heat. The volatile oil in the pharmaceutical preparation is fully dispersed and absorbed by the fine powder with a certain amount of heat. ; Reduce the temperature of the sealed pulverization system to 0°C, so that the micropowder containing volatile oil in the low temperature state is extruded by a high-speed rotating turbin...

Embodiment 2

[0023] Example 2 The method of wrapping the volatile oil in Shenqi Jianwei granules with low-temperature fine powder.

[0024] The raw materials and auxiliary materials of Shenqi Jianwei Granules are preprocessed into soft materials according to conventional methods, such as preparing the raw materials and auxiliary materials of Shenqi Jianwei Granules into soft materials according to the method of patent CN201410763715.2, and then the obtained soft materials are Under sealed conditions, the high-speed rotating turbine is used to pulverize to form fine powder. During the crushing process, the fine powder is repeatedly squeezed by the high-speed rotating turbine to generate a certain amount of heat. The volatile oil in the pharmaceutical preparation is fully dispersed and absorbed by the fine powder with a certain amount of heat. ; Reduce the temperature of the sealed pulverization system to 0°C, so that the micropowder containing volatile oil in the low temperature state is ext...

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Abstract

The invention discloses a method for wrapping essential oil with low-temperature micropowder. The method comprises the following steps: (1) crushing medicine materials and auxiliary materials in a pharmaceutical preparation through a high-speed rotating turbine in a sealed condition to form micropowder, repeatedly extruding the micropowder by virtue of the high-speed rotating turbine in the crushing process to generate a certain amount of heat, fully dispersing and adsorbing the essential oil in the pharmaceutical preparation with the micropowder with certain heat; and (2) lowering the temperature of a sealing crushing system, extruding the micropowder containing the essential oil through the high-speed rotating turbine to form a plurality of microspheres in a low-temperature state, so that the essential oil is wrapped with the microspheres. According to the method disclosed by the invention, the effective components of the essential oil and the raw and auxiliary materials in the preparation are firmly wrapped to form a microcapsule containing the essential oil; and the microcapsule has certain pressure resistance and heat resistance, and can completely meet drying and heating in stirring, extruding and drying processes in softwood preparation in a preparation production technology.

Description

technical field [0001] The invention belongs to the field of material processing, and in particular relates to a method for wrapping volatile oil with low-temperature micropowder. Background technique [0002] The volatile oils in traditional Chinese medicine are a kind of biologically active components, also known as essential oils. Usually it is a general term for the water-immiscible volatile oily components obtained from steam distillation of traditional Chinese medicine. Volatile oil is usually an oily liquid with a special strong odor, which can be evaporated at room temperature, soluble in concentrated ethanol and most organic solvents, and almost insoluble in water; it is sensitive to the influence of air, sunlight and temperature, and is easy to decompose spoiled. And the affinity of volatile oil and biofilm is poor, thereby influences curative effect, and its peculiar smell causes patient to be unacceptable. Oral preparations are the most used in research and cl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/16A61K36/85A61K36/752
Inventor 武俊明邓廷丽
Owner ZHONGXING PHARM CO LTD JIANGSU
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