Allergy and congestion relief and preparation method thereof

A technology of chlorpheniramine acid and phenylephrine hydrochloride, which is applied in the direction of pharmaceutical formulas, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problems of poor stability of preparations and achieve stability Good, low production energy consumption, simple preparation process

Active Publication Date: 2015-10-21
CHINA RESOURCES SANJIU MEDICAL & PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] Therefore, the technical problem to be solved by this invention is to overcome the technical defects that phenylephrine hydrochloride easily produces impurities such as adducts and poor preparation stability in the existing compound preparation, thereby proposing a kind of ibuprofen / phenylephrine hydrochloride / Chlorpheniramine maleate tablet and preparation method thereof

Method used

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  • Allergy and congestion relief and preparation method thereof
  • Allergy and congestion relief and preparation method thereof
  • Allergy and congestion relief and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0063] Embodiment 1: the present invention treats the Buprorenalin Namin tablet of cold

[0064] The ingredients are composed of:

[0065]

Embodiment 2

[0066] Embodiment 2: the present invention treats the Buprorenalin Namin tablet of cold

[0067] The ingredients are composed of:

[0068]

Embodiment 3

[0069] Embodiment 3: the present invention treats the Buprorenalin Namin tablet of cold

[0070] The ingredients are composed of:

[0071]

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Abstract

The invention discloses an allergy and congestion relief and a preparation method thereof. The prescription of the allergy and congestion relief comprises ibuprofen, phenylephrine hydrochloride, chlorpheniramine maleate, microcrystalline cellulose, pregelatinized starch, hydroxypropyl methylcellulose, sodium carboxymethyl starch, silicon dioxide, a film coating premixed agent, lactic acid and propyl gallate. Compared with the prior art, the prepared allergy and congestion relief has the beneficial effects that stability is good, the stability of key indexes such as impurities is obviously superior to that of launched products abroad, and the dissolution rate of medicines, especially the dissolution rate of the indissolvable medicine ibuprofen is equivalent to or slightly rapider than that of the launched products abroad.

Description

technical field [0001] The invention relates to a tablet for treating colds and a preparation method thereof, belonging to the field of pharmaceutical preparations. Background technique [0002] Influenza is clinical common disease and frequently-occurring disease. At present, the treatment of cold is still based on symptomatic treatment. Due to the diversity of cold symptoms, a single drug is often ineffective. However, compound preparations can target multiple cold symptoms at the same time and have the advantage of comprehensive control. They have gradually become mainstream products in the market. [0003] The components of common anti-cold medicines mainly include antipyretic and analgesic drugs, vasoconstrictor drugs, antihistamines, antitussive and expectorant drugs and antiviral drugs. Among them, the first choice of vasoconstrictor drugs is ephedrine drugs. However, ephedrines are precursor chemicals. The use of ephedrine compound preparations to produce drugs h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4402A61K9/28A61K47/38A61P11/00A61K31/192A61K31/137
Inventor 张艳斌刘志刚陈东余良钟马鹏岗孙亚洲
Owner CHINA RESOURCES SANJIU MEDICAL & PHARMA
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