Drug delivery device and method for eliminating a clearance of the piston rod for drug delivery devices
A technology of a delivery device and a piston rod, which is applied in the directions of drug devices, infusion sets, hypodermic injection devices, etc., can solve the problems of deviation of the first dose from the allowable dose accuracy limit and the like
Active Publication Date: 2015-10-28
SANOFI AVENTIS DEUTSCHLAND GMBH
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AI Technical Summary
Problems solved by technology
For many drugs, this loss is significant, causing the first dose to deviate significantly from the limits of allowable dose accuracy
Method used
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Embodiment Construction
[0134] figure 1 A cross-section of an example of a drug delivery device comprising a piston rod combination is shown. figure 1 A perspective view showing its details. The piston rod 1 is arranged to advance a bung 2, which is used to push out a dose of medicament, and may be arranged in a medicament container like a cartridge. A bearing 3 may be arranged between the piston rod 1 and the bung 2 in order to facilitate relative movement, in particular relative rotation, between the piston rod 1 and the bung 2 . The piston rod assembly is located in a housing comprising at least a body member 5 which may for example be an inner body 5 arranged in an outer body 4 . A drive member 6 is arranged to advance the piston rod 1 which is in threaded engagement with the inner body 5 and with the drive member 6 . The threaded engagement between the piston rod 1 and the inner body 5 can be formed by a thread 8 on the inner body 5 and the thread 8' on the piston rod 1, and the threaded enga...
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The piston rod arrangement is in an assembled state before use and comprises a piston rod (1 ), a bung (2), which is intended to be driven by the piston rod, a body member (5), and a drive member (6). The piston rod is threadedly engaged with the body member, and the drive member is threadedly engaged with the piston rod and movable relative to the body member. A mechanism is provided defining unit steps of movement of the drive member (6) and corresponding unit steps of movement of the piston rod (1 ). The piston rod is arranged in contact with the bung or at a distance from the bung that is less than a distance of one corresponding unit step of movement. When the piston rod, the bung and the drive member are assembled in the body member, the piston rod is advanced with respect to the body member towards the bung, until the piston rod is stopped by the bung. The drive member is rotated until the piston rod begins to advance again and the drive member is then stopped, and the piston rod is fixed at or near the position obtained.
Description
technical field [0001] The present invention relates to a drug delivery device and a method for eliminating play in a piston rod of a drug delivery device. Background technique [0002] A drug delivery device, in particular a pen-type injection device, comprises a bung for expelling a dose of drug and a piston rod to drive the bung. The piston rod can be provided with mechanisms for setting and delivering doses. At the end of assembly of the device, a gap is intentionally left between the end of the piston rod, which may be provided with a bearing, and the bung, which may be provided as part of the drug cartridge. This play is a result of the tolerances associated with the overall assembly components and the undesired pre-loading of the plug into the assembled device prior to first use. [0003] When the device is first used, the actual dose of drug delivered will be less than the set dose by an amount equal to the volume that the bung should have pushed out at the speed o...
Claims
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Patent Timeline
Login to View More IPC IPC(8): A61M5/315
CPCA61M5/3146A61M5/31515A61M5/31551A61M5/31585A61M2207/00A61M2207/10A61M2005/31516
Inventor D·A·普伦特里P·R·德拉珀D·R·默瑟N·雷卡亚P·格里芬R·维齐
Owner SANOFI AVENTIS DEUTSCHLAND GMBH