Oppositely-impacting quantitative atomization drug delivery apparatus

Abstract

The invention relates to an oppositely-impacting quantitative atomization drug delivery apparatus. The apparatus comprises a high-pressure gas generation assembly and a quantitative drug delivery pipe, a gas nozzle assembly disposed in an intoxication cabinet, and a low-speed fan disposed in the intoxication cabinet; the upper part of the quantitative drug delivery pipe is connected with the high-pressure gas generation assembly, a nozzle at the bottom of the quantitative drug delivery pipe is provided with ejection micropores; and the gas nozzle assembly is connected with the high-pressure gas generation assembly, and is arranged oppositely to the nozzle of the quantitative drug delivery pipe, and the top of the gas nozzle assembly is provided with ejection micropores. A drug liquid ejected by the quantitative drug delivery pipe clashes with a high-speed gas ejected by the gas nozzle assembly, thus the drug liquid is rapidly atomized, and is uniformly dispersed in the intoxication cabinet under the stirring effect of the low-speed fan. Compared with the prior art, the apparatus possesses the advantages that the drug liquid volume is accurately quantified, the drug liquid atomization efficiency is improved, the drug liquid is distributed uniformly, the drug liquid is prevented from settling, and the like.

Description

technical field [0001] The invention relates to a drug delivery device, in particular to a counter-type quantitative atomization drug delivery device. Background technique [0002] Inhalation toxicity is the toxic effect caused by exposure of foreign compounds through the respiratory tract. The inhalation toxicity laboratory can provide information for risk assessment of test substances by evaluating whether inhalable test substances, such as gases, volatile substances, aerosols or particles, can be absorbed through the respiratory tract and their inhalation toxicity. The drug delivery system for inhalation exposure is a key part of the inhalation exposure equipment used in this test. [0003] The concentration of the sample is of great significance to the reliability of the results of the inhalation toxicity test, especially when the measurement results of the concentration of harmful substances in the exposure cabinet are used to obtain the LC 50 (half inhalation lethal ...

AI Technical Summary

Problems solved by technology

This device can adjust the output frequency of the first pump and the spraying time of the atomization module to achieve quantitative liquid. This process needs to constantly explore the relationship between the output frequency, spraying time and the volume of the liquid medicine, which takes a long time and is very small. The deviation of the liquid will easily lead to the quantification of the liquid volume; in addition, the output of the liquid medicine needs to pass through complicated pipeline components, etc., which will easily cause the residue of the liquid medicine and lead to the concentration error of the medicine; due to the complicated internal structure of the device, it is difficult to clean. After administration, there are likely to be liquid residues at the joints, which will affect the later experiments

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