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Externally applied traditional Chinese medicine composition with anti-acne effect, phospholipid complex, preparation method and application thereof

A technology of phospholipid complexes and compositions, which is applied in the field of phospholipid complexes and skin care preparations, can solve the problem of not being able to improve acne-causing cosmetics, and achieve the effects of good transdermal absorption, good inflammatory factors, and fiber structure optimization

Active Publication Date: 2018-09-11
BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Bacteriostasis, regulation of oil secretion, reduction of androgen and other means can treat the acne that has grown well and control the skin to continue to grow acne, but they cannot improve or avoid the acne-causing problem of cosmetics. Few additives can solve the acne-causing problem. Cosmetics for acne to make it acne-free

Method used

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  • Externally applied traditional Chinese medicine composition with anti-acne effect, phospholipid complex, preparation method and application thereof
  • Externally applied traditional Chinese medicine composition with anti-acne effect, phospholipid complex, preparation method and application thereof
  • Externally applied traditional Chinese medicine composition with anti-acne effect, phospholipid complex, preparation method and application thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0067] The preparation of embodiment 1 Chinese medicine composition of the present invention

[0068] (1) After the following raw materials are pulverized into 50 meshes, they are weighed and mixed according to the weight ratio;

[0069] Salvia 45g, Clove 15g, Astragalus 10g, Licorice 10g, Pyracantha 10g, Marshmallow 6g.

[0070] (2) Absolute ethanol extraction: the mass volume ratio of raw material drug to absolute ethanol (g / ml) is 1:20, extract at 50°C for 4 hours;

[0071] (3) The extract that step (2) obtains is filtered with 200 meshes, then carries out suction filtration with diatomaceous earth and plate-and-frame filter, and suction filtration temperature is 45 ℃; 4000r / min, centrifugation time is 15 minutes;

[0072] (4) Remove all ethanol from the supernatant by vacuum rotary evaporation to obtain a concentrated solution, the rotary evaporation temperature is 45°C, and the vacuum degree is -0.1MPa;

[0073] (5) Vacuum-dry the concentrated solution in a vacuum dryi...

Embodiment 2

[0074] The preparation of embodiment 2 Chinese medicine composition of the present invention

[0075] (1) After the following raw materials are pulverized into 100 meshes, they are weighed and mixed according to the weight ratio;

[0076] Salvia 60g, Clove 20g, Astragalus 20g, Licorice 5g, Pyracantha 15g, Marshmallow 5g;

[0077] (2) Absolute ethanol extraction, the mass volume ratio of raw material drug to absolute ethanol g / ml is 1:10, extract at 40°C for 5 hours;

[0078] (3) The extract that step (2) obtains is filtered with 100 meshes, then carries out suction filtration with diatomaceous earth and plate-and-frame filter, and suction filtration temperature is 40 ℃; 3000r / min, centrifugation time is 20 minutes;

[0079] (4) Remove all ethanol from the supernatant by vacuum rotary evaporation to obtain a concentrated solution at a temperature of 45°C and a vacuum of -0.1MPa;

[0080] (5) Vacuum-dry the concentrated solution in a vacuum drying oven for 18 hours, wherein t...

Embodiment 3

[0081] The preparation of embodiment 3 Chinese medicine composition of the present invention

[0082] (1) After the following raw materials are pulverized into 50 meshes, they are weighed and mixed according to the weight ratio;

[0083] Salvia 40g, Clove 30g, Astragalus 30g, Licorice 20g, Pyracantha 5g, Marshmallow 10g;

[0084] (2) Absolute ethanol extraction, the mass volume ratio of raw material drug to absolute ethanol g / ml is 1:25, extract at 65°C for 3 hours;

[0085] (3) The extract that step (2) obtains is filtered with 100 meshes, then carries out suction filtration with diatomaceous earth and plate-and-frame filter, and suction filtration temperature is 65 ℃; 5000r / min, centrifugation time is 10 minutes;

[0086] (4) Remove all ethanol from the supernatant by vacuum rotary evaporation to obtain a concentrated solution at a temperature of 40°C and a vacuum of -0.08MPa;

[0087] (5) Vacuum-dry the concentrated solution in a vacuum drying oven for 36 hours, wherein ...

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Abstract

The invention discloses an externally-applied traditional Chinese medicine composition with effects on inhibiting acnes and preventing pocks, which is prepared from the following raw medicines in parts by weight: 40-60 parts of red sage root, 15-30 parts of clove, 10-30 parts of astragalus root, 5-20 parts of licorice, 5-15 parts of pyracantha and 5-10 parts of marshmallow. Experiments prove that the composition disclosed by the invention can be used together with commercially available cosmetics with an acnegenic effect to inhibit the acnegenic effect of the cosmetics, and the composition has good anti-bacterial and anti-grease effects and can damage the growing environment of bacteria to completely sterilize and inhibit the bacteria, thereby playing a role in treating acnes. The composition also has a certain optimized effect on the fiber structure of the skin so as to achieve a certain smoothing effect on the pocks, and also has a fading effect on other scars induced by skin injuries. The composition has a good effect on inhibiting inflammatory factors. The composition has the advantages that the raw materials are easy to acquire, the preparation method is simple and convenient, the composition is environment-friendly and safe and is easy to be accepted by consumers, and thus the composition has good application and market prospects.

Description

technical field [0001] The invention relates to an external Chinese medicine composition, in particular to an external Chinese medicine composition with anti-acne effect, a phospholipid complex and a skin care preparation prepared from the skin care composition. Background technique [0002] Acne is a chronic inflammatory skin disease caused by blockage of hair follicles and sebaceous glands and inflammation. It is common in young men and women in puberty. It mainly occurs on the face, neck, chest, back, shoulders and upper arms, forming papules. Chinese medicine calls it " Acne", Western medicine disease name "acne". During puberty, male hormones increase, sebaceous gland secretion increases, and at the same time, hair follicles and sebaceous glands are hyperkeratotic, and the flat dead cells that have fallen off the cuticle fall to the infundibulum of the hair follicle and combine with sebum to produce a mixture. If these mixtures cannot be discharged freely from the skin...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K8/9789A61K36/73A61P17/10A61P31/04A61K8/55A61Q19/00
Inventor 董银卯孟宏刘宇红曲召辉
Owner BEIJING TECHNOLOGY AND BUSINESS UNIVERSITY
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