45results about How to "Inhibit inflammatory factors" patented technology

The invention discloses a mesenchymal stem cell exosome as well as a preparation method and an application thereof, and belongs to the technical field of biomedicine. According to the invention, bonemarrow mesenchymal stem cells, adipose mesenchymal stem cells and skin mesenchymal stem cells are separated and cultured in vitro, exosomes in a cell culture supernatant are extracted by an ultracentrifugation method, and the exosomes are administrated in an articular cavity administration mode. The three exosomes derived from mesenchymal stem cells can significantly relieve related indications ofa rat with senile knee joint wear, such as improving Mankin score of a senile knee joint wear model mouse, inhibiting inflammatory factors and activating an RANK system.

The invention discloses a mild skin brightening body lotion, which comprises bacopa monniera extract, eugenol, hibiscus flower extract, jojoba seed oil, squalane, propylene glycol, glycerin, glyceryl stearate, stearyl alcohol Polyether‑21, hydrogenated olive oil and other ingredients. The mild plant active ingredients are non-irritating to the skin, and endow the product with significant anti-oxidation and antibacterial effects; the body milk of the present invention can replenish moisture to the skin, balance the skin tone, and brighten the skin color, making the skin fairer and more elastic; It can inhibit inflammatory factors and has a certain healing effect on inflamed skin.

The present invention discloses moisturizing, allergy-relieving and hair caring hair essence liquid applied to the head. The essence liquid is prepared from the following components in mass percentages: 0.5-5% of propylene glycol, 0.5-10% of glycerol, 0.01-0.1% of hydroxyethylcellulose, 0.1-5% of a moisturizing composition, 0.1-10% of a soothing composition, 0.1-1% of p-hydroxyacetophenone, 0.1-1%of hexanediol and the balance water. The essence liquid has very good moisturizing and allergy-relieving effects on hair.

The invention discloses application of a hydrogen molecule solid carrier in preparation of medicine for preventing and treating obesity related metabolic inflammation. According to the hydrogen molecule solid carrier, molecular hydrogen achieves a physiological effect, the carrier does not achieve the physiological effect, the reducing effect of hydrogen can be fully achieved, and prevention and treatment of obesity related metabolic inflammation are achieved from multiple levels. The application includes the steps of inhibiting increase of serum inflammatory factors in the generating process of obesity related metabolic inflammation, inhibiting increase of adipose tissue inflammatory factors, relieving adipose tissue dyslipidemia, inhibiting generation of oxidative damage in adipose tissue and inhibiting activation of inflammasome in the adipose tissue. The result shows that the hydrogen molecule solid carrier is fairly effective medicine for preventing and treating obesity related metabolic inflammation.

The invention discloses a cosmetic composition capable of relieving immediately and application thereof, which belong to the technical field of cosmetics. According to the cosmetic composition capableof relieving immediately, specific plant extracts are added to match functional components such as sodium hyaluronate with remarkable whitening and moisturizing effects, inflammatory factors such ashistamine can be inhibited and the expression intensity of TRPV1 can be reduced when the cosmetic composition is used, meanwhile, the skin barrier is effectively repaired, the damaged skin is relieved, and the skin is recovered and the health state is kept for a long time. The composition is free of additional chemical addition reagents, free of irritation to human skin and high in stability, andhas the characteristics of safety, mildness, storage resistance and high efficiency. The invention further discloses a cosmetic containing the cosmetic composition capable of relieving immediately.

The invention relates to a botanical drug, and discloses an application of schisanlactone E extracted from kadsura heteroclita in preparation of a drug for resisting rheumatoid arthritis. The schisanlactone E extracted from the kadsura heteroclita can effectively inhibit the proliferation of rheumatoid arthritis fibroblast-like synoviocytes (RAFLS), effectively inhibit the generation of lipopolysaccharide-induced inflammatory factors TNF-alpha, IL-1[beta] and IL-6 of the RAFLS and increase the expression level of IL-10, and has a relatively good anti-inflammatory effect. The occurrence rate ofAIA-induced rat arthritis can be effectively inhibited, the swelling degree of the rat toes is reduced, and the changes of pathology and radiology images of the rat toes are improved. The invention further discloses a drug with the schisanlactone E extracted from the kadsura heteroclita as an active ingredient, and the drug can be prepared into various dosage forms such as tablets, capsules or injections and is used for inhibiting the pathological changes caused by the rheumatoid arthritis and preventing bone joints from being damaged.

The present invention relates to an application of polydatin in preparation of a drug for treating and preventing intrauterine adhesions. The polydatin is an extract obtained by alcohol extraction from dried rhizomes and roots of reynoutria japonica belonging to polygonaceae plants, and various dosage forms of the drug for treating and preventing the intrauterine adhesion at least contain the polydatin. The polydatin is used as an active ingredient, has good anti-inflammatory and anti-fibrotic effects, is remarkable in effects, clear in mechanism of action and clear in target, and meets requirements for development of pharmaceutical preparations.

The invention discloses tobacco shreds containing a hyaluronic acid composition. The tobacco shreds are prepared from the following raw materials: a tobacco raw material, the hyaluronic acid composition, a bulking agent, an adhesive, a mildew preventive and spice. The invention further relates to a preparation method of the tobacco shreds containing the hyaluronic acid composition. According to the tobacco shreds containing the hyaluronic acid composition and the preparation method of the tobacco shreds, the hyaluronic acid composition serves as a humectant of the tobacco shreds containing thehyaluronic acid composition, the humectant of the tobacco shreds is effectively improved, the processing resistance of the tobacco shreds is improved, and the processing loss is reduced; meanwhile, the taste of the tobacco shreds is improved, irritation and dryness are reduced, and smoke is finer and smoother.

The invention relates to a solanum photeinocarpum fruit composition for damp-heat syndrome. The composition mainly comprises the following components: a solanum photeinocarpum fruit polysaccharide extract extracted from black purple mature fruits of solanum photeinocarpum and a solanum photeinocarpum fruit glycoside extract or a solanum photeinocarpum fruit glycoside inclusion compound extracted from green immature fruits of solanum photeinocarpum, wherein the solanum photeinocarpum fruit polysaccharide extract accounts for 0.1-5% of the mass of the composition, and the solanum photeinocarpumfruit glycoside extract or the solanum photeinocarpum fruit glycoside inclusion compound accounts for 0.5-5% of the mass of the composition. The invention also relates to application of the solanum photeinocarpum fruit composition. The extraction method of the extract in the composition distinguishes the maturity of fruits, and the fruits are respectively and effectively extracted, so that more beneficial components can be obtained.

The invention discloses novel application of carrageenan in preparing a medicament for treating serious hepatitis. The medicament can be used for inhibiting inflammatory reaction in serious hepatitis attaching process, so that attack or symptom worsening of serious hepatitis can be inhibited. Carrageenan has good curative effect in an endotoxin and D-galactosamine induced animal model; and the medicaments used in the application can be easily acquired, low in price and stable in properties, are convenient to store and transport, and have wide application prospect.

The invention belongs to the technical field of cosmetics, and particularly relates to a moisturizing and anti-inflammatory composition. The composition comprises the following main effective components of peony flower extract, beet root extract and sphingomonas gum. The composition plays a role in moisturizing similar to the vitamin D, improves the transcriptional activity of a vitamin D receptor, on one hand, promotes tight connection between epidermis, on the other hand, protects calcium ion against loss, so that mitochondrial respiration is promoted to supply energy to cells, and efficient energy supply can enhance skin barriers and immune functions; in the anti-inflammatory aspect, inflammatory factors are inhibited, and the inflammatory response of skin is reduced; and through the synergistic effect of the components, excellent 24-hour moisturizing, skin barrier repairing and couperose skin reducing effects are provided for the skin.