Application of carrageenan in preparing medicament for treating serious hepatitis
A technology for severe hepatitis and carrageenan, applied in the field of biomedicine, can solve the problems of inability to treat patients, increased incidence of severe cases, lack of therapeutic drugs, etc., and achieve the effects of low price, inhibition of seizures or aggravation of symptoms, and broad application prospects.
Inactive Publication Date: 2013-03-20
合肥博太医药生物技术发展有限公司
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Problems solved by technology
In recent years, with the changes in people's lifestyles and eating habits, and the impact of chronic viral hepatitis, the incidence of severe hepatitis has continued to rise. The direct consequence of severe hepatitis is liver failure, and the mortality rate of patients is extremely high. At the same time, there is a lack of effective therapeutic drugs. Clinically, liver replacement is the best treatment option, but there is a serious shortage of liver donors, and most patients cannot be treated. Therefore, the development of effective therapeutic drugs is of great significance for the treatment of this disease
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[0015] (Treatment of carrageenan injection solution preparations on endotoxin / D-galactosamine-induced severe hepatitis model)
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Abstract
The invention discloses novel application of carrageenan in preparing a medicament for treating serious hepatitis. The medicament can be used for inhibiting inflammatory reaction in serious hepatitis attaching process, so that attack or symptom worsening of serious hepatitis can be inhibited. Carrageenan has good curative effect in an endotoxin and D-galactosamine induced animal model; and the medicaments used in the application can be easily acquired, low in price and stable in properties, are convenient to store and transport, and have wide application prospect.
Description
Technical field [0001] The invention is the field of biomedical technology, which involves the application of Kara gums in drugs that are prepared to treat severe hepatitis. Background technique [0002] Severe hepatitis is a disease that seriously affects the health of the people.In recent years, with the changes in people's lifestyles, changes in eating habits, and the effects of chronic viral hepatitis, the incidence of severe disease has continued to rise. The direct consequence of severe hepatitis is liver failure, patient mortality rates, and lack of effective treatment drugs.Clinically, the liver is replaced with the best treatment plan, but the liver donor is seriously insufficient, and most of the patients cannot treat it. Therefore, the development of effective treatment of drugs is of great significance to the treatment of the disease.There are many causes of severe hepatitis, viruses, drugs, alcohol, etc. can lead to the onset of severe hepatitis.The biological mechan...
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IPC IPC(8): A61K31/731A61P1/16A61P29/00
Inventor 董磊
Owner 合肥博太医药生物技术发展有限公司
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