Application of hydrogen molecule solid carrier in preparation of medicine for preventing and treating obesity related metabolic inflammation

A technology of hydrogen molecules and drugs, applied in the fields of biology and medicine, can solve the problem of ineffective curative effect and so on

Inactive Publication Date: 2016-11-16
XI AN JIAOTONG UNIV
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  • Abstract
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  • Claims
  • Application Information

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Problems solved by technology

However, due to the extremely fast hydrogen diffusion ability, the problem of hydrogen dissipation in the hydrogen-rich liquid, whether it is in vitro dissipation, that is, the hydrogen-rich liquid begins to appear from the preparation process, and the real-time measurement of the experiment shows that the hydrogen molecule of the hydrogen-rich liquid is about 8 hours after the preparation is complete

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  • Application of hydrogen molecule solid carrier in preparation of medicine for preventing and treating obesity related metabolic inflammation
  • Application of hydrogen molecule solid carrier in preparation of medicine for preventing and treating obesity related metabolic inflammation
  • Application of hydrogen molecule solid carrier in preparation of medicine for preventing and treating obesity related metabolic inflammation

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Embodiment Construction

[0027] The present invention will be further described in detail below in conjunction with specific embodiments, which are explanations of the present invention rather than limitations.

[0028] 1. Experimental materials

[0029] The hydrogen molecule solid carrier is calcium and magnesium carbonates, accounting for more than 50% of the solid substance content, and is in the form of powder, granular, and amorphous solid forms. The substance includes but not only Hydrogenated Coral Calcium. In addition, the solid carrier itself is the same substance as above, including but not only coral calcium.

[0030] Hydrogenated coral calcium (coral calcium hydride, CCH), coral calcium (coral calcium, CC) was provided by Japan Creative Biotechnology Research Institute.

[0031]Tumor necrosis factor, interleukin-6, and lipid peroxidation index 4-hydroxynonenal were detected using commercial ELISA kits, which were purchased from Nanjing Jiancheng Bioengineering Institute; protein carbonyl...

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Abstract

The invention discloses application of a hydrogen molecule solid carrier in preparation of medicine for preventing and treating obesity related metabolic inflammation. According to the hydrogen molecule solid carrier, molecular hydrogen achieves a physiological effect, the carrier does not achieve the physiological effect, the reducing effect of hydrogen can be fully achieved, and prevention and treatment of obesity related metabolic inflammation are achieved from multiple levels. The application includes the steps of inhibiting increase of serum inflammatory factors in the generating process of obesity related metabolic inflammation, inhibiting increase of adipose tissue inflammatory factors, relieving adipose tissue dyslipidemia, inhibiting generation of oxidative damage in adipose tissue and inhibiting activation of inflammasome in the adipose tissue. The result shows that the hydrogen molecule solid carrier is fairly effective medicine for preventing and treating obesity related metabolic inflammation.

Description

technical field [0001] The invention belongs to the technical fields of biology and medicine, and relates to the application of hydrogen molecule solid carriers in the preparation of medicines for preventing and treating obesity-related metabolic inflammation. Background technique [0002] Obesity is the excessive accumulation of body fat caused by the imbalance of energy metabolism, which is closely related to the occurrence of various metabolic syndromes such as insulin resistance and atherosclerosis. Obesity itself is a chronic inflammatory disease that occurs in adipose tissue, and its typical features usually include the activation of inflammatory signaling pathways in adipose tissue cells, the release of inflammatory cytokines, and the infiltration of immune cells and other pathological changes. The inflammatory factors released by adipose tissue can also enter the circulatory system and affect the functions of other tissues and organs, causing the main therapeutic fac...

Claims

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Application Information

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IPC IPC(8): A61K33/00A61P3/04A61P29/00A23L33/00
CPCA61K33/00A23V2002/00A23V2200/3324
Inventor 刘健康龙建纲侯晨
Owner XI AN JIAOTONG UNIV
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