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Solanum photeinocarpum fruit composition for damp-heat syndrome and application thereof

A technology of Solanum nigrum fruit glycosides and compositions, which is applied in the field of plant fruit extract compositions, can solve problems such as lack of research or reports on the extraction of Solanum nigrum fruit, and achieve inhibition of tumor cell growth, high content of active components, and regulation of the body. The effect of immunity

Pending Publication Date: 2020-06-23
李明慧 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the prior art, there is no research or report on the extraction of the fruit of Solanum nigrum with different degrees of maturity

Method used

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  • Solanum photeinocarpum fruit composition for damp-heat syndrome and application thereof
  • Solanum photeinocarpum fruit composition for damp-heat syndrome and application thereof
  • Solanum photeinocarpum fruit composition for damp-heat syndrome and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Embodiment 1, the preparation of the polysaccharide extract A of Solanum nigrum L., the steps are as follows:

[0029] 1. Take the fresh or dried black and purple mature fruit of Solanum nigrum, extract the pigment of Solanum nigrum with acidic ethanol solution, and decolorize it. The weight-to-volume ratio of Solanum nigrum and acidic ethanol in g / mL is 1:3; the acidic ethanol solution is prepared by dissolving 0.1 mole of citric acid in 1 liter of 85% edible ethanol.

[0030] 2. Take the decolorized and less-flowered nightshade fruit, and extract it with water reflux or decoction for 3 times. The water consumption for each time is 1:5 according to the weight-to-volume ratio of nightshade fruit: water g / ml, and the extraction time is 1 hour each time. , combine the extracts, filter, intercept the solution containing polysaccharide components with a relative molecular weight of 5,000 to 100,000 Daltons, then concentrate to a relative density of 1.1, slowly stir and add ...

Embodiment 2

[0031] Embodiment 2, the preparation of Solanum nigrum Fructose Polysaccharide Extract B, its steps are as follows:

[0032] (1) Take the fresh or dried black and purple mature fruit of Solanum nigrum, extract the pigment of Solanum nigrum with edible alcohol, and decolorize it. The weight-to-volume ratio of the less-flowered Solanum nigrum fruit to the edible alcohol g / mL is 1:5; the alcohol content of the used edible alcohol is 80%.

[0033] (2) Take the less-flowered nightshade fruit after decolorization, and extract it twice with water reflux or decoction. The water consumption for each time is 1:5 according to the weight-volume ratio of nightshade fruit: water g / ml, and the extraction time for each time is 1.5 hours, combine the extracts, filter, intercept the solution containing polysaccharide components with a relative molecular weight of 5000-100000 Daltons, add papain to hydrolyze the glycoprotein, remove the glycoprotein by the isoelectric point method and boiling me...

Embodiment 3

[0034] Embodiment 3, the preparation of solanum nigrum glucoside extract, its steps are as follows:

[0035]Get the immature fruit fresh product of turquoise nightshade with few flowers, extract 2 times with 85% edible ethanol, the consumption of edible ethanol is according to the nightshade with little flowers: ethanol weight-to-volume ratio g / ml is 1:6, merges and extracts liquid, recover ethanol, remove impurities and decolorize with macroporous resin, then elute macroporous resin with 70% ethanol, collect eluent, recover ethanol, take concentrated solution and further remove impurities with 0.1mol / L sodium hydroxide solution, collect Precipitate and dry to obtain Solanum nigrum fructoside extract.

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Abstract

The invention relates to a solanum photeinocarpum fruit composition for damp-heat syndrome. The composition mainly comprises the following components: a solanum photeinocarpum fruit polysaccharide extract extracted from black purple mature fruits of solanum photeinocarpum and a solanum photeinocarpum fruit glycoside extract or a solanum photeinocarpum fruit glycoside inclusion compound extracted from green immature fruits of solanum photeinocarpum, wherein the solanum photeinocarpum fruit polysaccharide extract accounts for 0.1-5% of the mass of the composition, and the solanum photeinocarpumfruit glycoside extract or the solanum photeinocarpum fruit glycoside inclusion compound accounts for 0.5-5% of the mass of the composition. The invention also relates to application of the solanum photeinocarpum fruit composition. The extraction method of the extract in the composition distinguishes the maturity of fruits, and the fruits are respectively and effectively extracted, so that more beneficial components can be obtained.

Description

technical field [0001] The present invention relates to a plant fruit extract composition, in particular to the composition of Solanum nigrum fruit for damp-heat syndrome, and also relates to the use of the composition of Solanum nigrum fruit. Background technique [0002] Damp-heat syndrome, in the field of traditional Chinese medicine, refers to the general term for the syndromes of both dampness and heat after the evil of dampness invades the human body. The syndrome shows initial aversion to cold, but the heat is not cold, sweating, chest fullness, and thirst. Drink, it won't heal for a long time. Damp-heat syndrome includes damp-heat febrile disease and damp-heat syndrome in various clinical departments. [0003] The original plant of traditional Chinese medicine Solanum nigrum is Solanum nigrum L., a plant of the genus Solanaceae. Solanum nigrum has the functions of clearing heat and detoxification, reducing swelling and dissipating stagnation, reducing inflammation ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/81A61K8/9789A61K47/69A23L33/105A61P43/00A61P17/02A61P39/02A61P29/00A61P35/00A61P17/04A61P1/16A61P37/04A61P11/14A61Q19/00A61K131/00
CPCA61K36/81A61K8/9789A61K47/6951A23L33/105A61P43/00A61P17/02A61P39/02A61P29/00A61P35/00A61P17/04A61P1/16A61P37/04A61P11/14A61Q19/00A61K2236/331A61K2236/30A61K2800/10A61K2236/333
Inventor 李明慧张锦超郝爱凤杨占波李欣陈海静
Owner 李明慧
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