Application of polydatin in preparation of drug for treating and preventing intrauterine adhesions

A technology for intrauterine adhesion and polydipside is applied to the application field of polydactin in the preparation of medicines for treating and preventing intrauterine adhesions, which can solve the problems such as the research on intrauterine adhesions that have not been found, and achieve the improvement of the number of glands and the reduction of deposition. Effect

Inactive Publication Date: 2019-07-16
THE FIRST HOSPITAL OF LANZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Studies in recent years have found that polydatin has other pharmacological effects. In addition to discovering that polydatin has biological effects in anti-in

Method used

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  • Application of polydatin in preparation of drug for treating and preventing intrauterine adhesions
  • Application of polydatin in preparation of drug for treating and preventing intrauterine adhesions
  • Application of polydatin in preparation of drug for treating and preventing intrauterine adhesions

Examples

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Example Embodiment

[0125] Example An application of polydatin in the preparation of a medicine for the treatment and prevention of uterine adhesions: dissolve 125 mg of polydatin powder in 2 mL of dimethyl sulfoxide (DMSO), and then dilute it with normal saline to form The corresponding dosing concentration. Finally, the medicines of each concentration are separately packed into the sterilized EP tubes, sealed, marked, and stored at -20°C for later use, thus preparing the polydatin injection that can treat and prevent intrauterine adhesions.

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Abstract

The present invention relates to an application of polydatin in preparation of a drug for treating and preventing intrauterine adhesions. The polydatin is an extract obtained by alcohol extraction from dried rhizomes and roots of reynoutria japonica belonging to polygonaceae plants, and various dosage forms of the drug for treating and preventing the intrauterine adhesion at least contain the polydatin. The polydatin is used as an active ingredient, has good anti-inflammatory and anti-fibrotic effects, is remarkable in effects, clear in mechanism of action and clear in target, and meets requirements for development of pharmaceutical preparations.

Description

technical field [0001] The invention relates to the field of biotechnology, in particular to the application of polydatin in the preparation of medicines for treating and preventing intrauterine adhesions. Background technique [0002] Intrauterine adhesions (IUA), also known as Asherman syndrome, is the formation of adhesions in the uterine cavity or cervix due to various factors, causing patients to often have abnormal menstruation, chronic pelvic pain and reproductive system disorders. Intrauterine adhesions seriously affect the physical and mental health of women of childbearing age. The disease is mostly caused by abortion and curettage. With the continuous development and improvement of diagnosis and treatment technology, the detection rate of intrauterine adhesions has also increased accordingly, accounting for about 90% of women of childbearing age suffering from intrauterine adhesions. However, there is no good treatment for intrauterine adhesions in clinical prac...

Claims

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Application Information

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IPC IPC(8): A61K31/7034A61P41/00
CPCA61K31/7034A61P41/00
Inventor 王一青刘莹张学红高雪林丁媛武露明
Owner THE FIRST HOSPITAL OF LANZHOU UNIV
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