The invention relates to the field of skin care products, in particular to a skin activating and whitening essence liquid and a preparation method thereof. The skin activating and whitening essence liquid comprises 1,3-propylene glycol, butylene glycol, nicotinamide, panthenol, hydrolyzed collagen, trehalose, tocopherol, glycerin, 3-o-ethyl ascorbic acid and cyanocobalamin. The nicotinamide, the 3-o-ethyl ascorbic acid, the panthenol, the cyanocobalamin, the tocopherol and multivitamins synergistically cooperate with the butanediol, the hydrolyzed collagen, the trehalose and other raw materials to prepare the skin activating and whitening essence liquid, and the skin activating and whitening essence liquid can improve skin metabolism, promote the absorption of skin care raw materials, effectively improve the self-protection of the skin, and improve skin dullness, declined elasticity, pigmentation and other poor skin conditions; vitamin B12 and vitamin C complement with each other to improve the skin metabolism, promote the absorption of nutrient raw materials, effectively improve the self-protection of the skin and improve skin dullness, declined elasticity and other poor skin conditions. Long term use of the skin activating and whitening essence liquid can dilute spots, make the skin color uniform, whiten and brighten the skin, clear the skin, remove skin imperfections and make the skin shining, permeable, bright and white.