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A kind of medical tissue protective cleaning liquid and its preparation method and application

A cleaning solution and tissue technology, applied in the field of biodegradable polymer materials, can solve the problems of dry environment survival and fertility decline, bacterial infection intensification, etc. The effect of adhesion

Active Publication Date: 2018-01-26
NKD PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] It is well known that a humid and hypoxic environment is crucial to the wound healing process, but a humid environment is often accompanied by aggravated bacterial infection. Bacteria are more likely to survive and reproduce in a humid environment, while survival and reproduction in a dry environment are average. greatly reduced
[0007] Since the existing technology cannot meet the clinical requirements, it is of great importance to develop a new medical tissue protective cleaning solution with moisturizing, lubricating and antibacterial effects

Method used

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  • A kind of medical tissue protective cleaning liquid and its preparation method and application
  • A kind of medical tissue protective cleaning liquid and its preparation method and application
  • A kind of medical tissue protective cleaning liquid and its preparation method and application

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Effect test

Embodiment 1

[0039] Medical tissue protective cleaning solution, which contains carboxymethyl chitosan (M W =9000), the percentage by weight is 1%, water-soluble starch, the percentage by weight is 1%, glycerol, the percentage by weight is 1%, and the rest are phosphate buffer solution with a pH value of 7-7.5.

Embodiment 2

[0041] Medical tissue protection cleaning solution, wherein carboxymethyl chitosan (M W =20000), the percentage by weight is 0.5%, the percentage by weight of water-soluble starch is 0.5%, the percentage by weight of glycerol is 0.1%, and the rest is a phosphate buffer solution with a pH value of 7-7.5.

Embodiment 3

[0043] Medical tissue protective cleaning solution, carboxymethyl chitosan (M W =20000), the percentage by weight is 5%, the percentage by weight of water-soluble starch is 2%, the percentage by weight of glycerol is 0.5%, and the rest is a phosphate buffer solution with a pH value of 7-7.5.

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PUM

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Abstract

The invention relates to a degradable medical tissue protective cleaning solution and its preparation method and application. The protective cleaning solution is a colorless, transparent, viscous liquid, which includes three components. The first component is hydrophilic and antibacterial The raw material mainly refers to chitosan derivatives, and its weight percentage is 0.1%-10%; the second component is hydrophilic and moisturizing raw materials, mainly referring to starch derivatives, and its weight percentage is 0.5%-5%; the third component is a physiological balance solution, mainly referring to 0.9% sodium chloride and PBS phosphate buffer saline; the three components are formed by physical stirring and mixing.

Description

technical field [0001] The invention belongs to the field of biodegradable polymer materials, and in particular relates to a medical tissue protection cleaning solution and a preparation method and application thereof. Background technique [0002] In the process of surgical operation and wound treatment, medical workers often adopt various measures, such as hemostatic agent, anti-inflammatory agent, wound irrigation agent, etc. Currently, the commonly used medical tissue cleaning solution is sodium chloride injection. Good sex, clean and pollution-free, is of great significance for debridement during surgery. But sodium chloride injection still has weak point as medical cleaning liquid, for example has no moisture retention, lubricity and bacteriostasis. [0003] At present, if some skin wounds need cleaning, infection prevention and postoperative adhesion prevention, antibiotics, sodium hypochlorite, polyaminopropyl biguanide (polyhexamethylene), sodium carboxymethylcellu...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/722A61L31/04A61L31/16A61L31/06
Inventor 徐小雨陶秀梅牟昳尚丽霞
Owner NKD PHARMA CO LTD
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