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A kind of pharmaceutical composition for treating rhinitis and preparation method thereof

The technology of a composition and a medicine is applied in the field of pharmaceutical compositions for treating rhinitis and the field of preparation thereof, which can solve problems such as difficulty in radical cure, and achieve the effects of small dosage, anti-inflammatory effect and definite curative effect.

Active Publication Date: 2016-07-13
SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine mostly uses anti-inflammatory, anti-allergic, pain relief and surgical treatment, which is generally difficult to cure

Method used

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  • A kind of pharmaceutical composition for treating rhinitis and preparation method thereof
  • A kind of pharmaceutical composition for treating rhinitis and preparation method thereof
  • A kind of pharmaceutical composition for treating rhinitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] The present embodiment is made of the following Chinese medicine ingredients in parts by weight:

[0044] Xanthium 150, Mubihua 100, Morus alba 130, Scutellaria baicalensis 60, Loofah 60, Angelica dahurica 50, Licorice 60, Honeysuckle 150, Mint 60, Scrophulariaceae 70, Phellodendron 60, Ephedra 30.

[0045] Its preparation method comprises the following steps:

[0046] (1) Extraction of volatile oil: get wood pen flower, honeysuckle, angelica dahurica and peppermint, add the water of 12 times of the weight of these four medicinal materials, soak time is 1h, adopt steam distillation method, extract 6h with volatile oil extractor, get volatile oil and Medicine dregs.

[0047] (2) Inclusion of volatile oil: according to the weight of the volatile oil, add 6 times of β-cyclodextrin, at a temperature of 45° C., for 2.5 hours to obtain the inclusion compound of volatile oil.

[0048] (3) Extraction of the rest of the medicinal materials in the prescription: Weigh the Xanthi...

Embodiment 2

[0141] The present embodiment is made of the following Chinese medicine ingredients in parts by weight:

[0142] Xanthium 140, Mubihua 90, Morus alba 140, Scutellaria baicalensis 70, Loofah 50, Angelica dahurica 50, Licorice 70, Honeysuckle 120, Mint 70, Scrophulariaceae 60, Phellodendron 50, Ephedra 40.

[0143] Its preparation method: with embodiment 1

[0144] The antibacterial, anti-inflammatory, anti-allergic and analgesic effects of the pharmaceutical composition of this embodiment were studied by using animal experiments and in vitro antibacterial tests. The results are the same as in Example 1. The pharmaceutical composition of this example has good analgesic effect and anti-inflammatory activity, and has no obvious oral toxicity, and can be taken for a long time.

[0145] clinical test results

[0146] Using method: with embodiment 1.

[0147] The use effect verification is as follows:

[0148] 22 examples of patients with chronic rhinitis, aged 20-71 years old, t...

Embodiment 3

[0153] The present embodiment is made of the following Chinese medicine ingredients in parts by weight:

[0154] Xanthium 160, Mubihua 95, Morus alba 120, Scutellaria baicalensis 50, Loofah 70, Angelica dahurica 70, Licorice 50, Honeysuckle 160, Mint 50, Scrophulariaceae 65, Phellodendron 70, Ephedra 35.

[0155] Its preparation method: with embodiment 1

[0156] The antibacterial, anti-inflammatory, anti-allergic and analgesic effects of the pharmaceutical composition of this embodiment were studied by using animal experiments and in vitro antibacterial tests. The results are the same as in Example 1. The pharmaceutical composition of this example has good analgesic effect and anti-inflammatory activity, and has no obvious oral toxicity, and can be taken for a long time.

[0157] clinical test results

[0158] Using method: with embodiment 1.

[0159] The use effect verification is as follows:

[0160] 24 cases of patients with chronic rhinitis, aged 20-71 years old, take...

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Abstract

The invention discloses a pharmaceutical composition for treating rhinitis and a preparation method thereof. The medicinal ingredients of the pharmaceutical composition are made of the following traditional Chinese medicine ingredients in parts by weight: Fructus Xanthii 120-180, Mubihua 80-120 , Morus alba 100‑150, Scutellaria baicalensis 40‑80, Loofah 40‑80, Angelica dahurica 40‑80, Licorice 40‑80, Honeysuckle 100‑180, Mint 40‑80, Scrophulariaceae 40‑80, Phellodendron 40‑80, Ephedra 20‑50. The preparation method comprises the following steps: extraction of volatile oils from penflower, honeysuckle, angelica dahurica and peppermint, inclusion of volatile oils, extraction of other components and combination pharmacy. The pharmaceutical composition provided by the invention has the advantages of small dosage, convenient administration, wide application range, definite curative effect, safety and reliability, no recurrence of cure, rogue drug properties and no side effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a pharmaceutical composition for treating rhinitis and a preparation method thereof. Background technique [0002] Rhinitis is a common and frequently-occurring disease without seasonality. According to statistics, 37% of the people in the country suffer from rhinitis, which can occur from children to the elderly, which is a serious threat to human health; with the increase of air pollution, smog Frequent, rhinitis patients may continue to increase. For the treatment of rhinitis, there are no particularly effective medicines on the domestic and foreign markets at present. Western medicine mostly uses anti-inflammatory, anti-allergy, pain relief and surgical treatment, which are generally difficult to cure, easy to relapse, and have large side effects. Clinical manifestations of rhinitis: mainly nasal congestion, excessive nasal discharge, decr...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/808A61P11/02A61P29/00
Inventor 向梅先尹娴陈晓冰张浪吴丽
Owner SOUTH CENTRAL UNIVERSITY FOR NATIONALITIES