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Biological agent for reducing blood pressure and preparation method of biological agent

A biological preparation and blood pressure lowering technology, which is applied to medical preparations containing active ingredients, blood diseases, drug combinations, etc., can solve the problems of western medicine not suitable for long-term use, weakened elasticity, hardening of blood vessels, etc., to improve blood viscosity, Effect with long shelf life and few side effects

Inactive Publication Date: 2016-01-20
上海善力健生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicines for reducing blood pressure mainly focus on dilating blood vessels, and the elasticity of blood vessels becomes weak and hardens during the continuous expansion process. Therefore, people who use antihypertensive drugs for a long time are likely to cause hardening and rupture of blood vessels, and lead to cerebral vascular embolism. , stroke and other diseases
Therefore, western medicine is not suitable for long-term use

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The biological preparation used in this example for lowering blood pressure includes the following components and contents in parts by weight: 25 parts of nattokinase, 20 parts of eucommia leaf extract, 16 parts of kudzu root extract and 18 parts of wild chrysanthemum flower extract.

[0032] Among them, vitamin K in nattokinase 2 The content of <10PPM, and the activity of nattokinase is 8000Fu.

[0033] The preparation method of eucommia leaf extract is as follows: add eucommia leaves to 6-8 times the amount of water, soak and extract twice at 50-70°C to obtain an extract, and then concentrate the extract at 55-65°C to a density of 1.05 -1.08g / cm 3 to obtain a concentrated solution, and then put the concentrated solution in an adsorption resin, elute with 50-70wt% ethanol solution, and dry to obtain the Eucommia leaf extract.

[0034] The preparation method of the kudzu root extract is as follows: add the kudzu root to 60-80wt% ethanol solution of 6-8 times the amoun...

Embodiment 2

[0054] The biological preparation used in this example for lowering blood pressure includes the following components and contents in parts by weight: 20 parts of nattokinase, 15 parts of eucommia leaf extract, 10 parts of kudzu root extract and 10 parts of wild chrysanthemum flower extract.

[0055] Among them, vitamin K in nattokinase 2 The content of <10PPM, and the activity of nattokinase is 4000Fu.

[0056] The preparation method of eucommia leaf extract is as follows: add eucommia leaves to 6-8 times the amount of water, soak and extract twice at 50-70°C to obtain an extract, and then concentrate the extract at 55-65°C to a density of 1.05 -1.08g / cm 3 to obtain a concentrated solution, and then put the concentrated solution in an adsorption resin, elute with 50-70wt% ethanol solution, and dry to obtain the Eucommia leaf extract.

[0057] The preparation method of the kudzu root extract is as follows: add the kudzu root to 60-80wt% ethanol solution of 6-8 times the amoun...

Embodiment 3

[0065] The biological preparation used in this example for lowering blood pressure includes the following components and contents by weight: 30 parts of nattokinase, 30 parts of eucommia leaf extract, 20 parts of kudzu root extract and 20 parts of wild chrysanthemum flower extract.

[0066] Among them, vitamin K in nattokinase 2 The content of <10PPM, and the activity of nattokinase is 5000Fu.

[0067] The preparation method of eucommia leaf extract is as follows: add eucommia leaves to 6-8 times the amount of water, soak and extract twice at 50-70°C to obtain an extract, and then concentrate the extract at 55-65°C to a density of 1.05 -1.08g / cm 3 to obtain a concentrated solution, and then put the concentrated solution in an adsorption resin, elute with 50-70wt% ethanol solution, and dry to obtain the Eucommia leaf extract.

[0068] The preparation method of the kudzu root extract is as follows: add the kudzu root to 60-80wt% ethanol solution of 6-8 times the amount, reflux...

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Abstract

The invention relates to a biological agent for reducing blood pressure and a preparation method of the biological agent. The biological agent is prepared from the following components in parts by weight: 20 to 30 parts of nattokinase, 15 to 30 parts of eucommia ulmoides leaf extract, 10 to 20 parts of pueraria root extract and 10 to 20 parts of wild chrysanthemum extract; during preparation, various components are weighed according to weight parts and are placed into a three-dimensional mixer for mixing for 15 to 25 minutes; the mixture passes through a sieve with 40 to 80 meshes, and the operation is repeated for 2 to 3 times to obtain the biological agent. Compared with the prior art, the biological agent disclosed by the invention has the advantages that blood vessel elasticity can be improved, and the blood vessel is rejuvenated; meanwhile, thrombolysis in blood is promoted, blood fat is reduced and blood quality is improved; the biological agent has stabilizing and pressure reducing actions, and is simple in preparation process, quick in response, wide in application people, low in dose, fewer in side effects, good in stability, long in shelf life, convenient in administration, easy to carry, low in cost and suitable for large-scale production.

Description

technical field [0001] The invention belongs to the technical field of biopharmaceuticals, and relates to a biological preparation for lowering blood pressure and a preparation method thereof. Background technique [0002] It is well known that high blood pressure is a very high risk factor for cardiovascular and cerebrovascular diseases. Hypertension is a chronic disease characterized by sustained elevation of arterial blood pressure. One of the main causes of the disease is the spasm of the peripheral arterioles of the human body, which increases the resistance of the peripheral arteries of the human body, resulting in increased blood pressure and the formation of hypertension. It causes lesions in the heart, brain, kidney and other vital organs with corresponding consequences. At present, regardless of the prevalence rate of hypertension, its mortality rate and disability rate are increasing rapidly, its development trend is very worrying. The 2015 China Cardiovascular ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P9/12A61P7/02A61K36/488
Inventor 许宏华韩超
Owner 上海善力健生物科技有限公司
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