Genetics detecting device of embryo before implantation

Abstract

The invention relates to the field of biology, and provides a genetics detecting device of an embryo before implantation. The genetics detecting device of the embryo before implantation comprises a message unit 100, an amphiphilic haplotype creating module 200, a candidate embryo haplotype building module 300, a candidate embryo haplotype parental source determining module 400 and a judgment module 500 for judging whether a candidate embryo carries gene defects. According to the genetics detecting device of the embryo before implantation provided by the invention, a more accurate genetics diagnosis of the embryo before implantation can be given, so as to select out healthy embryos.

Description

technical field [0001] The invention relates to the field of biology, in particular to a genetic detection device before embryo implantation. Background technique [0002] Genetic diseases not only seriously affect the physical and mental health of patients, but also bring great burdens to society and families, and are very difficult to treat. Even if they can be treated, the cost is relatively expensive. Therefore, preimplantation genetic diagnosis can avoid the birth of fetuses with genetic diseases. It is of great significance to improve the quality of the population and reduce the social burden. [0003] Preimplantation Genetic Diagnosis (PGD) is a new diagnostic technique formed on the basis of the rapid development of assisted reproduction and molecular biology. It has a history of more than 20 years. Preimplantation genetic diagnosis is a very good measure for improving population quality, controlling birth defects and treating infertility. In 2010, British scientis...

AI Technical Summary

Problems solved by technology

So far, on the one hand, single-cell gene amplification still cannot completely avoid the problem of allele drop-out (ADO)

ADO is due to the fact that one of the alleles is not amplified due to too little testing material, or the amplified amount is not enough to reach the detection level. It will cause misjudgment of PGD results, and in extreme cases, it can directly lead to an embryo failure. Therefore, it is very critical to overcome the misjudgment caused by ADO; on the other hand, the existing methods for analyzing embryo haplotypes are also very complicated and error-prone

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