Calcitriol capsule type drop and preparation method thereof

Abstract

The present invention relates to a calcitriol capsule type drop and a preparation method thereof. The calcitriol capsule type drop comprises contents and a capsule shell, wherein the contents comprise calcitriol, butyl hydroxyanisole, butylated hydroxytoluene, and grease, and the capsule shell comprises gelatin, titanium dioxide, sunset yellow, iron oxide, water, sorbitol and glycerin. Compared with the drop in the prior art, the drop of the present invention has characteristics of high safety, easy use, strong targeting property, and the like.

Description

Technical field

[0001] The invention belongs to the field of calcitriol preparations, and relates to calcium supplement drugs, in particular to a calcitriol capsule-type drop and a preparation method thereof. technical background

[0002] Calcitriol is one of the most important metabolically active products of vitamin D3 in the human body. Normally, calcitriol is synthesized in the kidney from its precursor 25-hydroxycholesterol. The daily physiological synthesis of calcitriol in the human body is about 0.5-1.0ug. During the period of active bone formation, its synthesis volume also slightly increased. Calcitriol can promote the absorption of calcium in the intestines and regulate bone calcification. At present, no calcitriol capsule drops are on the market at home and abroad, and the only available dosage forms are raw materials, soft capsules, injections, capsules and ointments. As a calcium supplement, calcitriol occupies a certain position in the calcium supplement market....

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