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Medicine for treating postoperative adhesive intestinal obstruction

A post-operative technique for adhesive intestinal obstruction, applied in the field of traditional Chinese medicine, can solve problems such as lack of systemicity, achieve the effects of improving ultrastructure, comprehensive evaluation of curative effect, and reducing the degree of intra-abdominal adhesions

Inactive Publication Date: 2016-03-30
庄小侃
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] After reviewing relevant literature, although traditional Chinese medicine enemas are widely used in the treatment of AIO, they are limited to clinical efficacy observations and lack of systematicness. In addition, it is rare to discuss the protective effect of traditional Chinese medicine enemas on animals with adhesive intestinal obstruction. Experiment and Mechanism Research

Method used

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  • Medicine for treating postoperative adhesive intestinal obstruction
  • Medicine for treating postoperative adhesive intestinal obstruction

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0056] The present invention also provides the preparation method of above-mentioned enema mixture, it comprises:

[0057] The first step is to weigh raw rhubarb, Glauber’s salt, wuyao, toosendan, corydalis, white peony root, rehmannia root, red peony root, angelica, peach kernel, panax notoginseng powder, fried Atractylodes macrocephala, Codonopsis pilosula, Moutan bark, Alisma, Thyme grass, and Badu powder are mixed together, and the weighed Magnolia officinalis, Citrus aurantium, Tangerine peel, fried radish, licorice, Cyperus cyperi, Poria, and Coptis are mixed together;

[0058] The second step is to mix raw rhubarb, Glauber's salt, wuyao, toosendan, corydalis, white peony root, rehmannia glutinosa, red peony root, angelica, peach kernel, Panax notoginseng powder, fried Atractylodes macrocephala, Codonopsis pilosula, Moutan bark, zebra Put Xie, Thymecao, and Badu powder into the multi-functional extraction tank, and add water to the multi-functional extraction tank. Radi...

Embodiment 1

[0065] Embodiment 1 enema mixture 1

[0066] Weigh raw rhubarb 15g, Glauber's salt 5g, black medicine 30g, Toosendan 20g, Corydalis 20g, Radix Paeoniae Alba 25g, Rehmannia glutinosa 25g, Radix Paeoniae Rubra 20g, Angelica 25g, peach kernel 15g, Panax notoginseng powder 5g, 20g of fried Atractylodes macrocephala, 20g of Codonopsis pilosula, 15g of Moutan bark, 20g of Alisma, 20g of thyme grass, 5g of Badu powder, mixed together, 15g of Magnolia officinalis, 20g of Citrus aurantium, 25g of tangerine peel, 15g of fried radish , licorice 20g, Cyperus cyperi 20g, Poria cocos 35g, and Coptis 15g are mixed together, and the raw rhubarb, Glauber's salt, black medicine, Toosendan, Corydalis, white peony root, rehmannia root, red peony root, angelica, peach kernel , Panax notoginseng powder, fried Atractylodes macrocephala, Codonopsis pilosula, Moutan cortex, Alisma, thymeca, and Badu powder are put into the multi-functional extraction tank, and water is added to the multi-functional ex...

Embodiment 2

[0067] Embodiment 2 enema mixture 2

[0068] Weigh raw rhubarb 15g, Glauber’s salt 5g, black medicine 30g, Toosendan 15g, Corydalis 20g, Radix Paeoniae Alba 20g, Rehmannia glutinosa 25g, Radix Paeoniae Rubra 15g, Angelica 25g, peach kernel 15g, Panax notoginseng powder 5g, fried Atractylodes macrocephala 15g, Codonopsis 15g, Moutan cortex 10g, Alisma 15g, Thyme grass 15g, Badu powder 5g mixed together, the weighed Magnolia officinalis 15g, Citrus aurantium 15g, Chenpi 25g, fried radish 10g , 15g licorice, 15g Cyperus cyperi, 35g Poria cocos, 10g Coptis chinensis, mixed together raw rhubarb, Glauber's salt, black medicine, Toosendan, Corydalis, white peony root, rehmannia root, red peony root, angelica, peach kernel , Panax notoginseng powder, fried Atractylodes macrocephala, Codonopsis pilosula, Moutan cortex, Alisma, thymeca, and Badu powder are put into the multi-functional extraction tank, and water is added to the multi-functional extraction tank. 10 times the mass of Chi...

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Abstract

The invention provides a medicine for treating postoperative adhesive intestinal obstruction. Active pharmaceutical ingredients of the medicine include rhubarb, mirabilite, officinal magnolia bark, Fructus Aurantii, combined spicebush root, szechwan chinaberry fruit, dried tangerine peel, fried radish seed, rhizoma corydalis, liquorice root, white paeony root, rehmannia root, red paeony root, Chinese angelica, peach seed, nutgrass galingale rhizome, radix notoginseng powder, fried largehead atractylodes rhizome, Indian buead, radix codonopsis, tree peony bark, oriental waterplantain rhizome, Chinese bastardtoadflax herb, herb of Szechwan sida and coptis root. The medicine has the beneficial effects that by adopting the medicine provided by the invention, the degree of adhesion in abdominal cavities of rats can be reduced, intestinal mucosa injuries can be obviously alleviated, inflammatory reactions of tissues can be reduced, the ultrastructures of intestinal mucosae can be improved and the intestinal barrier function can be enhanced; the comprehensive assessment of the curative effects is better than that of the curative effects of western medicines, thus fully revealing the advantages of the medicine.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a medicine for treating the formation of adhesive intestinal obstruction after operation. Background technique [0002] Adhesive ileus (Adhesive Intestinal Obstruction, AIO) is a disease caused by intra-abdominal adhesions that cause obstruction of intestinal content passage. It is the most common type of intestinal obstruction and is a long-term, unpredictable problem after abdominal surgery. , with the increase in abdominal surgery, its incidence is on the rise. Once adhesive ileus occurs, it is difficult to cure it. Often, it needs to be loosened by surgery once, and the adhesion will be aggravated once, so that it cannot be treated by surgery. AIO can not only cause local damage to the digestive tract, but also cause systemic physiological disorders, leading to the release of a large number of related media and cytokines, affecting ultrastructural change...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8905A61P1/00A61K33/04
Inventor 庄小侃
Owner 庄小侃
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