45 results about "Abdominal adhesions" patented technology

A thermal rotary massager is provided. The thermal rotary massager according to current application is comprised of two noble rotary electric connectors to heat four heaters embedded inside of four massage balls while the massage balls are rotating. Each electric connector according to current application is comprised of a seating member and one metal bearing connection parts for conduction of electricity. The seating member fits on ribs that is formed on the upper surface of a case and does not rotate. However, the massage balls are heated to emit far-infrared ray and anions while they are rotate-ably massaging user's body. It is possible due to the rotary connectors.

A device for supporting the abdominal region of the user. A fabric band is sized to be worn surrounding the abdominal region which supports strategically placed hook and loop regions. A pair of segments of stretch material, also having hook and loop regions at least one of their ends are capable of being selectively and removably appended to the fabric band to apply compression or restriction to the user's abdomen. The device is particularly useful in helping one to restore abdominal muscle and control particularly after pregnancy.

Disclosed herein is a drive device of an electrode channel for strengthening core muscles of an abdominal region, which can improve circulation of body fluid in a body cavity of the abdominal region and activate muscle membrane tissues inside / outside the abdominal cavity. The drive device includes a wearable instrument worn by a user over an abdominal region, a plurality of electrode channels formed by an electrode pair of a positive-terminal strip and a negative-terminal strip provided on the wearable instrument and contacting a body of the user, and a frequency supply unit for generating and selectively applying Russian current having a middle frequency and interference-wave current between the positive-terminal strip and the negative-terminal strip. Control is performed such that Russian current and interference-wave current are selectively applied to a positive-terminal strip of one of the plurality of electrode channels and a negative-terminal strip of another electrode channel.

An abdominal exercise device comprises a center bar, a handle assembly attached to a first end portion of the center bar and that is adapted to be grasped by a user, an abdominal press assembly mounted to the center bar between first and second end portions thereof and having an abdominal contact surface that is spaced from the center bar and is adapted to rest against an abdominal region of a user; and a stabilizer mounted to the second end portion of the center bar and that is adapted to stabilize the center bar when the abdominal contact surface rests against a user. The user can perform a leg lift exercise, a crunch exercise, or both exercises in unison.

The present invention relates to a wound dressing for use in negative-pressure wound therapy, in particular for wounds in the abdominal region. The wound dressing comprises a first flexible film with a first and a second side, with the first side being provided for application on the wound bed, more particularly on exposed internal organs or on the greater omentum, and with the first film furthermore having a multiplicity of openings distributed across the area. Moreover, the wound dressing comprises at least three conduit sections, applied to the second side of the first film, made of a flexible elastomeric material with a thickness (H) of at most 20 mm, with each of the conduit sections having at least one continuous cavity, and with each of the conduit sections having a flat design. Furthermore, the wound dressing is distinguished by virtue of the fact that, with the exception of the openings situated at the ends, each of the conduit sections has no further openings.

When an amount of visceral fat is measured using ultrasonic waves during medical examination of metabolic syndrome, three contact positions are defined on the surface of the abdominal region, and three distances inside the living body are measured by bringing a probe into contact with the surface of the abdominal region at the contact positions. Specifically, three measurement paths having a starting point at the center of the descending aorta are set, and the distances from the center to a surface of the fat layer adjacent to the surface of the body (inner surface of the subcutaneous layer) in the measurement paths are observed. An approximate area of a visceral fat region can be determined from the three distances and two angles defined by the three measurement paths, and an index value is calculated on the basis of the area. A probe holder having three holding portions is desirably used.

Belonging to the field of organic polymer compound preparation or chemical processing, the invention provides a tension-free hernia patch and a preparation method thereof. The patch provided in the invention has good toughness and strength match, no adverse reaction in the human body, and excellent biocompatibility, and is free of inflammation and foreign body reaction. When the patch is implanted into organisms, abdominal adhesions and intestinal fistulas are greatly reduced, so that the patch is a good material for incisional hernias, abdominal hernias, stomal hernias, umbilical hernias and other herniorrhaphies. The patch includes a basal layer made of a non-absorbable material and a surface coating made of an absorbable material. The surface coating is softer, and can be completely absorbed by the human body in 60 days, thus providing time for combination of the basal layer and surrounding tissues. The patch provided in the invention has a simple preparation process and a low manufacturing cost. As a medical tension-free hernia patch, it has excellent comprehensive performance, and is a safe and reliable patch, thus having great social and economic value.

An abdominal exercise device comprises a center bar, a handle assembly attached to a first end portion of the center bar and that is adapted to be grasped by a user, an abdominal press assembly mounted to the center bar between first and second end portions thereof and having an abdominal contact surface that is spaced from the center bar and is adapted to rest against an abdominal region of a user; and a stabilizer mounted to the second end portion of the center bar and that is adapted to stabilize the center bar when the abdominal contact surface rests against a user. The user can perform a leg lift exercise, a crunch exercise, or both exercises in unison.

The invention discloses a pharmaceutical composition for promoting the healing of postoperative wound, which relates to the technical field of traditional Chinese medicine. The pharmaceutical composition is prepared from active elements by weight: 12-16 parts of astragalus root, 12-16 parts of eucommia bark, 8-12 parts of angelica sinensis, 8-12 parts of phellodendron bark, 8-12 parts of kudzu vine root, 8-12 parts of dragon's blood, 15-20 parts of radix achyranthis bidentatae, 15-20 parts of aloe vera, 15-20 parts of peach kernels, 15-20 parts of dried tangerine, 15-20 parts of radix sophorae flavescentis, 15-20 parts of sappanwood and 10-15 parts of honeysuckle. The pharmaceutical composition provided by the invention can effectively promote the wound healing and prevent abdominal adhesion.

The invention provides a medium-molecular-weight hydroxyethylated starches applied to abdominal cavity chemotherapy drug carrier agent, wherein the molecular weight Mw of the medium-molecular-weight hydroxyethylated starches is 60000-600000 dalton, molar degree of substitution is 0. 15-0. 5 and hydroxyethylating substitution ratio in C2 and C6 is >=5. The invention provides carrier liquid including the medium-molecular-weight hydroxyethylated starches and the chemotherapy drug to make the big bulk extend existing time in the abdominal cavity with lasting high concentration through using the carrier liquid, which can contact the drug with the visceral and peritoneal surface in a large area to invade the remained nodules and caner stove to enhance antineoplastic effect to reduce the abdominal cavity adhesion.

The invention relates to surgical anti-adhesion flushing liquid, which belongs to the technical field of medicine. The surgical anti-adhesion flushing liquid is prepared from sodium hyaluronate, medicine water and any one kind of materials of sodium chloride or glycine or glucose or mannite or sorbierite. The surgical anti-adhesion flushing liquid provided by the invention is mainly prepared from the sodium hyaluronate as major effective ingredients, and the surgical anti-adhesion flushing liquid can be used for abdominal adhesion, adhesive ileus and the like after the surgical abdominal operation.

When an amount of visceral fat is measured using ultrasonic waves during medical examination of metabolic syndrome, three contact positions are defined on the surface of the abdominal region, and three distances inside the living body are measured by bringing a probe into contact with the surface of the abdominal region at the contact positions. Specifically, three measurement paths having a starting point at the center of the descending aorta are set, and the distances from the center to a surface of the fat layer adjacent to the surface of the body (inner surface of the subcutaneous layer) in the measurement paths are observed. An approximate area of a visceral fat region (20) can be determined from the three distances and two angles defined by the three measurement paths, and an index value is calculated on the basis of the area. A probe holder is desirably used during the above-described measurement. The probe holder includes three holding portions that selectively hold the probe.

The invention relates to a soft tissue repair patch and a preparation method thereof. The patch is prepared by taking mammalian skin tissues as a raw material by the following steps: carrying out pretreatment to remove subcutaneous auxiliary tissues, preparing a skin patch, carrying out primary decellularization, carrying out cross-linking modification, carrying out secondary decellularization, finally carrying out cleaning and cutting, carrying out drying and compounding, and carrying out terminal sterilization. The biological decellularized tissue patch prepared by the method not only has acomplete collagen three-dimensional structure, but also has the characteristics of good mechanical property, abdominal cavity adhesion prevention and the like. The patch product provided by the invention is suitable for repair of various soft tissue injuries and abdominal wall defects in surgical operations, and can also be used as a biological scaffold material in the field of biological engineering.

The invention discloses a pharmaceutical composition for promoting the healing of postoperative wound, which relates to the technical field of traditional Chinese medicine. The pharmaceutical composition is prepared from active elements by weight: 12-16 parts of astragalus root, 12-16 parts of eucommia bark, 8-12 parts of angelica sinensis, 8-12 parts of phellodendron bark, 8-12 parts of kudzu vine root, 8-12 parts of dragon's blood, 15-20 parts of radix achyranthis bidentatae, 15-20 parts of aloe vera, 15-20 parts of peach kernels, 15-20 parts of dried tangerine, 15-20 parts of radix sophorae flavescentis, 15-20 parts of sappanwood and 10-15 parts of honeysuckle. The pharmaceutical composition provided by the invention can effectively promote the wound healing and prevent abdominal adhesion.

The invention relates to application of a cGAS-STING signal channel inhibitor in preparation of a product for preventing or treating abdominal adhesion, and belongs to the technical field of biological medicines. The invention finds that peritoneal dialysis causes that a peritoneal mesothelial cell cGAS-STING pathway and downstream protein thereof are activated, inflammatory factors are generated, and the peritoneal mesothelial cell secretes a chemotactic factor CCL2 (MCP-1) participating in macrophage recruitment, so that migration of macrophages can be promoted, and abdominal adhesion is caused. The cGAS-STING signaling pathway inhibitor can be used for relieving the effects, so that the aim of treating abdominal adhesion is fulfilled.

The invention discloses an environmentally friendly low molecular weight heparin injection abdominal belt, comprising a flat belt body and a plurality of groups of marking units, wherein the marking units are uniformly and detachably mounted on the flat belt body. In accordance with the present invention, the belt is clean, prevents breeding of bacteria, is reusable, has high environmental protection value, is easy to wear, has a wide application range and is suitable for patients with different sizes of abdominal circumference; its flat band can be injected into the abdominal region of patients with low molecular weight heparin compression, can effectively prevent patients with abdominal subcutaneous hemorrhage, especially for poor resistance to the body, easy to appear 75% of the subcutaneous hemorrhage phenomenon. For an 70-80-year-old patient, the abdominal band is safer to use, can prevent the same part of the abdomen of the patient from missing injection or repeated injection, ismore safe and reliable, can eliminate the inaccurate identification of the marking unit, can prevent the injection of low molecular weight heparin into the navel of the patient, and can avoid the occurrence of danger.

The invention provides a compound traditional Chinese medicine cataplasm for treating canine diarrhea and a production process of the cataplasm, and relates to the technical field of veterinary medicine preparation. The compound traditional Chinese medicine cataplasm is prepared jointly by a traditional Chinese medicine extractum and a cataplasm auxiliary material. The traditional Chinese medicineextractum consists of the following substances by weight: 15 parts of pitted smoked plum, 25 parts of dried persimmon, 6 parts of terminalia chebula, 6 parts of coptis chinensis, 6 parts of curcuma aromatica, 15 parts of humulus scandens, 9 parts of pomegranate peels, 9 parts of bayberry roots, and 6 parts of nutmeg. The cataplasm auxiliary material consists of the following substances by weight:3 parts of distilled water, 3 parts of gelatin, 4 parts of glycerin, 4 parts of sodium polyacrylate, 4 parts of arabic gum, 5 parts of polyethylene glycol 400, 0.3 part of azone, and 0.2 part of zincoxide. According to the present invention, the deficiencies of prior art are overcomed, the prepared medicine is osmotic delivered by abdominal adhesion of the cataplasm, the dosage of the cataplasmis controllable, the irritation to skin is small, the osmotic absorption effect is good, the blood medicine concentration is stable, the treatment prognosis is good, and the compound traditional Chinese medicine cataplasm is suitable for promotion and use.

The invention discloses the preparation and application of degradable, biocompatible and high-strength chitin hydrogel. The preparation method is as follows: add the cross-linking agent dropwise into the chitin solution with a concentration of 5-7% at -10-10°C and stir for 1-2 hours, then use the tape casting method to prepare the gel, and then put it in at a temperature of -10-10°C. °C, the concentration is 80-100% in a coagulation bath for 6-8 hours of physical cross-linking, and finally washed with water to obtain chitin hydrogel. The hydrogel prepared by the invention is degradable, has good biocompatibility and high mechanical strength. The hydrogel prepared by the invention has great potential in biomedical applications such as bone injury repair, abdominal adhesion prevention, drug delivery and the like.

The invention discloses an absorbable chitin-based composite patch and an application thereof. The absorbable chitin-based composite patch is a mesh composed of chitin-based fibers or threads respectively having a surface coating; the chitin-based fibers or threads are insoluble in water, the main chain of the molecular structure of the chitin-based fibers or threads is polyglucosamine and contains an acyl group and a hydrophilic group, the total molar percent content of the acyl group is greater than or equal to 70%, and the total molar percent content of the hydrophilic group is less than 30%; and the surface coating is a water-soluble aminoglycan coating. The absorbable chitin-based composite patch is implanted in an abdominal wall in the operations of abdominal wall defect repairing and hernia repairing, can reduce the inflammatory response in the acute stage, reduce abdominal adhesions, promote the growth of the tissue cells and the synthesis of an extracellular matrix and accelerate the defect repairing of the abdominal walls in the physiologic repairing stage after the operation, and is gradually degraded after the abdominal wall defect repairing, and degradation products are absorbed and utilized by local tissue cells to further promote the abdominal wall defect repairing, so the absorbable chitin-based composite patch has no residual in bodies after being completely degraded, and no foreign matters exist in the bodies.

The invention discloses an absorbable chitin-based composite patch and an application thereof. The absorbable chitin-based composite patch is a mesh composed of chitin-based fibers or threads respectively having a surface coating; the chitin-based fibers or threads are insoluble in water, the main chain of the molecular structure of the chitin-based fibers or threads is polyglucosamine and contains an acyl group and a hydrophilic group, the total molar percent content of the acyl group is greater than or equal to 70%, and the total molar percent content of the hydrophilic group is less than 30%; and the surface coating is a water-soluble aminoglycan coating. The absorbable chitin-based composite patch is implanted in an abdominal wall in the operations of abdominal wall defect repairing and hernia repairing, can reduce the inflammatory response in the acute stage, reduce abdominal adhesions, promote the growth of the tissue cells and the synthesis of an extracellular matrix and accelerate the defect repairing of the abdominal walls in the physiologic repairing stage after the operation, and is gradually degraded after the abdominal wall defect repairing, and degradation products are absorbed and utilized by local tissue cells to further promote the abdominal wall defect repairing, so the absorbable chitin-based composite patch has no residual in bodies after being completely degraded, and no foreign matters exist in the bodies.

The invention discloses an application of a traditional Chinese medicine preparation which is made from rhubarb root and rhizome, peach seeds, crystallized sodium sulfate, safflowers, yanhusuo and radish seeds to prepare a medicine used for inhibiting abdominal fibroblast propagation, and discloses an application of the traditional Chinese medicine preparation to prepare a medicine for lowering fibroblast III collagen mRNA expression level. Based on the prior art, the traditional Chinese medicine preparation made from rhubarb root and rhizome, peach seeds, crystallized sodium sulfate, safflowers, yanhusuo and radish seeds is subjected to deep research. It is found from the research that the traditional Chinese medicine preparation can lower fibroblast III collagen mRNA expression level, inhibits abdominal fibroblast propagation, and provides a new idea and prospects for a medicine used for preventing and treating abdominal adhesion.

A method for evaluating an intestinal anastomosis stent is provided. By establishing an animal model of mechanical intestinal obstruction, an intestinal anastomosis stent implantation environment is simulated after intestinal tumor surgery in patients. It was observed that in the digestive tract anastomosis after intestinal severance under this intestinal obstruction animal model, the implantation of the anastomosis stent can promote wound healing at the intestinal anastomosis site, and the degree of abdominal adhesion is reduced during the healing process, and the intestinal bursting pressure strength is well restored; at the same time, according to the tissue section analysis of this site, it can be seen that its tissue healing process conforms to the physiological healing law and is better than the healing of the group without stent implantation. Moreover, from the expression of the degree of inflammation, the expression of new blood vessels, and the degree of fibrosis, it can be judged by comparing the stent implantation group and the group without stent implantation whether the stent to be tested has a significant advantage in promoting healing after intestinal anastomosis in this mechanical intestinal obstruction animal model. This provides an intuitive detection method for evaluating new materials for preparing intestinal anastomosis stents.

The invention relates to application of tetrahydroberberrubine in preparation of a medicine for preventing or treating intestinal adhesion diseases. Due to the fact that abdominal adhesion can cause bleeding, colorectal obstruction, female infertility and the like, existing treatment modes are laparoscopes or biological barrier material biological membranes, however, due to high cost and more serious tissue damage, postoperative tissue healing is troubled. Tetrahydroberberrubine has good prevention and treatment effects on abdominal adhesion, especially intestinal adhesion, and can inhibit expression of inflammatory factors and reduce inflammatory response at the same time. Therefore, tetrahydroberberrubine is suitable for prevention and treatment of abdominal adhesion, especially intestinal adhesion diseases.

The invention discloses kiwi fruit extracellular vesicle supported injectable hydrogel with active oxygen scavenging capacity as well as a preparation method and application of the kiwi fruit extracellular vesicle supported injectable hydrogel, and belongs to the cross technical field of biomedical materials and clinical medicine. Comprising the following raw materials: water-soluble chitosan (CS), polyvinyl alcohol (PVA), an active oxygen responsive chain segment construction macromonomer (Linker), a cross-linking agent and a drug-containing kiwi fruit extracellular vesicle. The injectable hydrogel is prepared by preparing the raw materials into an aqueous solution and carrying out a cross-linking reaction, and aims to optimize the postoperative recovery process and prevent the occurrence of abdominal adhesion by integrating a multi-effect treatment strategy of wound healing, inflammatory reaction control and tissue regeneration promotion.

The invention relates to the technical field of biological medicines, and particularly discloses application of deoxyribonuclease I in preparation of a medicine for treating wrapped peritoneal sclerosis. The application finds that deoxyribonuclease I can inhibit METs, can effectively reduce expression of METs in peritoneal tissues of a mouse with wrapped peritoneal sclerosis, and can also significantly improve the abdominal adhesion score, peritonitis infiltration, adhesion region collagen deposition area and peritoneal thickness of the mouse with wrapped peritoneal sclerosis; according to the present invention, the target METs is introduced to treat the wrapped peritoneal sclerosis so as to improve the pathological change related to the wrapped peritoneal sclerosis, such that the new wrapped peritoneal sclerosis prevention and treatment strategy is constructed by using the target METs to treat the wrapped peritoneal

The invention discloses injectable hydrogel for inhibiting adhesion after an abdominal cavity operation and a preparation method of the injectable hydrogel, and belongs to the cross technical field of biomedical materials and clinical medicine. The honeysuckle plant exosome is prepared from the following raw materials: water-soluble chitosan (CS), hyaluronic acid (HA), an active oxygen responsive chain segment construction macromonomer (Linker), a medicine-loaded honeysuckle plant exosome solution and a cross-linking agent. The raw materials are mixed and subjected to a cross-linking reaction, and the injectable hydrogel is prepared. According to the preparation method, water-soluble chitosan, hyaluronic acid and active oxygen responsive chain segments are used for constructing a macromonomer, genipin is used as a biological cross-linking agent, and the honeysuckle plant exosome containing drugs is loaded into injectable hydrogel, so that the purposes of eliminating postoperative abdominal inflammation and repairing and treating wounds are achieved, and the preparation method is simple and convenient. Therefore, postoperative abdominal cavity tissue adhesion can be synergistically treated and / or prevented.

The invention provides an enteral nutrition preparation applicable to postoperative gastrointestinal dysfunction recovery and a preparation method of the enteral nutrition preparation. The effective components of the enteral nutrition preparation comprise senna leaf extract, bifidobacterium, lactobacillus acidophilus, lactobacillus delbrueckii, fructo-oligosaccharide, galacto-oligosaccharide, xylo-oligosaccharide, decavitamin, composite electrolyte and the like through mixing. The enteral nutrition preparation can effectively improve postoperative patient gastrointestinal dysfunction and has important clinical significance in preventing postoperative ileus, abdominal adhesion and long-term no exhaust of patients, accelerating postoperative patient recovery and shortening length of stay. The preparation method is simple and suitable for mass industrial production.

The invention discloses a traditional Chinese medicine composition treating abdominal distension after the abdominal surgery. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 20 to 40 parts of radix notoginseng, 10 to 20 parts of mulberry leaves, 12 to 22 parts of herba lysimachiae, 5 to 15 parts of dried orange peel, 4 o 12 parts of radix aucklandiae, 6 to 12 parts of rhizoma cyperi, 5 to 13 parts of hawthorn, 8 to 17 parts of semen raphani, 1 to 10 parts of radix aucklandiae, 5 to 12 parts of pericarpium arecae, 6 to 12 parts of rhizoma sparganii, 3 to 7 parts of dark malt, 10 to 18 parts of ginger processed pinellia tuber, and 3 to 9 parts of semen pruni japonicae. The traditional Chinese medicine composition is remarkable incurative effect, capable of alleviating the abdominal distension after the abdominal surgery, free from side effects and simple and practical.

The application discloses a preparation method of an in-situ hydrazone bond injectable hydrogel and application thereof to preventing abdominal cavity adhesion, and belongs to the field of medical biomaterials. The application takes 8-arm-PEG10000-CHO with an aldehyde group at a terminal and 8-arm-PEG10000-HZ with a hydrazine group at a terminal as raw materials, forms a hydrazone bond through a Schiff base reaction, and obtains PCA supermolecular hydrogel through in-situ construction; the preparation method of the application does not need a chemical crosslinking agent, can quickly form a gel at room temperature, is simple and controllable in process, and the prepared hydrogel has excellent injectability, self-healing performance, biodegradability and biocompatibility, can form a stable physical barrier in-situ on an abdominal surgery wound, effectively inhibits inflammatory cell infiltration and collagen fiber deposition, has a significant prevention effect on light, medium and severe abdominal cavity adhesion, and especially still has excellent protection capability in a severe inflammatory adhesion model induced by talc, thereby providing a safe and effective new scheme for preventing and treating postoperative abdominal cavity adhesion.

Belonging to the field of organic polymer compound preparation or chemical processing, the invention provides a tension-free hernia patch and a preparation method thereof. The patch provided in the invention has good toughness and strength match, no adverse reaction in the human body, and excellent biocompatibility, and is free of inflammation and foreign body reaction. When the patch is implanted into organisms, abdominal adhesions and intestinal fistulas are greatly reduced, so that the patch is a good material for incisional hernias, abdominal hernias, stomal hernias, umbilical hernias and other herniorrhaphies. The patch includes a basal layer made of a non-absorbable material and a surface coating made of an absorbable material. The surface coating is softer, and can be completely absorbed by the human body in 60 days, thus providing time for combination of the basal layer and surrounding tissues. The patch provided in the invention has a simple preparation process and a low manufacturing cost. As a medical tension-free hernia patch, it has excellent comprehensive performance, and is a safe and reliable patch, thus having great social and economic value.