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Medicine composition for treating encephalatrophy and preparation method of medicine composition

A composition and a technology for brain atrophy, which are applied in the directions of drug combinations, pharmaceutical formulas, active ingredients of heterocyclic compounds, etc., can solve the problems of difficult to cure brain marrow, gradually emptying, etc.

Inactive Publication Date: 2016-05-04
JINAN XINGYI MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the treatment of this disease, modern medicine can only treat its mental symptoms, and it is difficult to cure its characteristics of "insufficient marrow sea" and "brain marrow gradually empty"

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Embodiment 1: The pharmaceutical composition and preparation method thereof for the treatment of brain atrophy

[0039] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating brain atrophy are: papiliochrome II 30g root grass 4380g shield fruit grass 3650g liensinine 65g asarin 6g willow licorice 14g;

[0040] Preparation:

[0041] (1) According to the ratio of raw materials, take papiliochrome II, stock grass, scutellaria scutellaria, liensinine, asarin, and willow licorice, mix them evenly, and use ethanol with a concentration of 21% by weight as a solvent, Warm immersion extraction at 33°C, the number of extractions is 17 times, each extraction time is 1.5 hours, and the amount of solvent used each time is 22.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and the extract A is recovered Ethanol, concentrated to a relative density of 1.13, filtered, the drug solutio...

Embodiment 2

[0044] Embodiment 2: The pharmaceutical composition for the treatment of brain atrophy and its preparation method

[0045] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating brain atrophy are: papiliochrome II 20g root grass 4390g shield fruit grass 3600g liensinine 90g asarin 5g lilycyrrhizine 18g;

[0046] Preparation:

[0047] (1) According to the ratio of raw materials, take papiliochrome II, stock grass, scutellaria scutellaria, liensinine, asarin, and willow licorice, mix them evenly, and use ethanol with a concentration of 21% by weight as a solvent, Warm immersion extraction at 33°C, the number of extractions is 17 times, each extraction time is 1.5 hours, and the amount of solvent used each time is 22.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and the extract A is recovered Ethanol, concentrated to a relative density of 1.13, filtered, the drug solution pas...

Embodiment 3

[0050] Embodiment 3: the pharmaceutical composition and preparation method thereof for the treatment of brain atrophy

[0051] The composition and parts by weight of the crude drug of the pharmaceutical composition for treating brain atrophy are: papiliochrome II 40g root grass 4370g shield fruit grass 3700g liensinine 40g asarin 7g lilycyrrhizine 10g;

[0052] Preparation:

[0053] (1) According to the ratio of raw materials, take papiliochrome II, stock grass, scutellaria scutellaria, liensinine, asarin, and willow licorice, mix them evenly, and use ethanol with a concentration of 21% by weight as a solvent, Warm immersion extraction at 33°C, the number of extractions is 17 times, each extraction time is 1.5 hours, and the amount of solvent used each time is 22.5 times the total weight of the raw material drug, filtered to obtain medicinal residue A and extract A, and the extract A is recovered Ethanol, concentrated to a relative density of 1.13, filtered, the drug solution...

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PUM

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Abstract

The invention discloses a medicine composition for treating encephalatrophy and a preparation method of the medicine composition. The medicine composition is prepared from papiliochrome II, whole grass of northern bedstraw, whole grass of thyrocarpus sampsonii hance, neferine, asarinin and tabersonine according to a proportion. The medicine composition can be prepared into various dosage forms according to conventional preparation technologies, and is significant in treatment effect when used for treating encephalatrophy.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, and in particular relates to a pharmaceutical composition for treating brain atrophy and a preparation method thereof. Background technique [0002] Brain atrophy refers to a type of neuropsychiatric disease that atrophies due to organic lesions in the brain itself due to various reasons. Brain atrophy includes pediatric brain atrophy and adult brain atrophy. More common with the elderly. The main clinical symptom of atrophy is dementia, especially in the elderly. Brain atrophy belongs to the category of "dementia", "forgetfulness", "vertigo", "atrophy syndrome" and "tremor" in traditional Chinese medicine. Traditional Chinese medicine believes that although the disease is located in the brain, it is closely related to the functions of the viscera, and the pathological mechanism belongs to deficiency in origin and excess in superficiality. [0003] Brain atrophy in adult...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P25/28A61P25/00A61K31/198A61K31/4725A61K31/36A61K31/4745
CPCA61K36/74A61K9/2031A61K9/2059A61K9/4866A61K31/198A61K31/36A61K31/4725A61K31/4745A61K36/30A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2236/55
Inventor 不公告发明人
Owner JINAN XINGYI MEDICAL TECH
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