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Antibacterial gel special for gynecology and preparation method thereof

A gel, gynecological technology, applied in the field of gynecological external medicines, can solve the problems that the medicine cannot reach the vaginal folds, and cannot comprehensively perform the drug anti-inflammatory treatment, etc., and achieves the effects of rapid diffusion and improved utilization.

Inactive Publication Date: 2016-05-04
FUJIAN AINVREN BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there are suppository treatment methods for these gynecological diseases. The medicine is placed in the vagina, but the medicine in the suppository can not reach the vaginal folds, so it cannot fully play the role of anti-inflammatory drug treatment.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A special antibacterial gel for gynecology, comprising the following raw materials in weight fractions: 20-45 parts of Kochia chinensis, 15-30 parts of Cnidium chinensis, 40-60 parts of Cortex Phellodendri, 20-35 parts of Chinese toon bark, Patrinia chrysalis 30 to 45 parts, 15 to 30 parts of a hundred parts, 10 to 20 parts of pomegranate peel, 1 to 2 parts of borneol, and 1 to 2 parts of curcuma.

[0029] Further, pharmaceutically acceptable auxiliary materials are included, and the auxiliary materials include gel matrix, skin penetration enhancer, preservative, moisturizer and antioxidant for enhancing the stability of the gel matrix, etc.; the gel matrix is ​​card One or more of Boomer, sodium carboxymethylcellulose, hydroxypropylmethylcellulose, polyvinyl alcohol, sodium alginate, and tragacanth gum; the skin penetration enhancer is azone; the The antiseptic is sorbic acid, paraben, etc.; the moisturizing agent is glycerin, propylene glycol, etc.; the antioxidant is...

Embodiment 2

[0042] A special antibacterial gel for gynecology, comprising the raw materials of the following weight fractions: 30 parts of Kochia chinensis, 25 parts of Cnidium chinensis, 45 parts of Phellodendron cortex, 30 parts of Chinese toon bark, 40 parts of Patrinia chrysalis, 25 parts of Baibu, 15 parts of pomegranate peel, 1.5 parts of borneol, 1.2 parts of curcuma.

[0043] Further, pharmaceutically acceptable auxiliary materials are included, and the auxiliary materials include gel matrix, skin penetration enhancer, preservative, moisturizer and antioxidant for enhancing the stability of the gel matrix, etc.; the gel matrix is ​​carboxyl Sodium methylcellulose and sodium alginate; The skin penetration accelerator is Azone; The preservative is sorbic acid; The moisturizing agent is glycerin; The antioxidant is the antioxidant BHT (2,6- di-tert-butyl-p-cresol).

[0044]Further, the sodium carboxymethylcellulose and sodium alginate are 2 parts; the azone is 5 parts; the sorbic ac...

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PUM

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Abstract

The embodiment of the invention discloses an antibacterial gel special for gynecology and a preparation method thereof. The antibacterial gel adopts belveder fruit, common cnidium fruit, barks of Chinese corktree, tree-of-heaven ailanthus bark, dahurian patrinia herb, sessile stemona root, pomegranate rind, borneol and curcuma zedoary in compatibility, and adopts a pharmaceutically acceptable auxiliary material as a gel matrix, and the raw materials are extracted by using a supercritical CO2 extraction method to prepare a gel. When in use, the gel can effectively cover plica parts of a vagina, can be absorbed in the vagina through skin, can sterilize and diminish inflammation comprehensively, and has relatively strong effects on various colpitis, cervicitis, pruritus vulvae, peculiar smells, abnormal menstruation and the like caused by bacteria, moulds, trichomonad and the like; and the gel has no side effect in use, and can adjust human body immunity. The gel can still be used for a long time without inflammation, can achieve prevention and maintenance effects on gynecological vaginal health, can prevent gynecological inflammation, and meanwhile can maintain the vagina, regulate the environment in the vagina to be in a healthy state, and slow down the aging of the vagina.

Description

technical field [0001] The invention relates to gynecological external use medicines, in particular to a special antibacterial gel for gynecology and a preparation method thereof. Background technique [0002] Vaginitis, pelvic inflammatory disease, cervicitis, and cervical erosion in gynecological diseases are common and frequently-occurring diseases, which seriously threaten women's health. Due to the particularity of female reproductive organs, gynecological inflammation has become a common and frequently-occurring disease in adult women. Its clinical manifestations are diverse, the etiology is complex, and it is often accompanied by a variety of serious complications, which has a great impact on women's life and work. Vaginitis is a general term for various vaginal mucosal diseases caused by different etiologies. In a normal physiological state, due to the characteristics of anatomical tissues, the vagina has a natural defense function against the invasion of pathogens....

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/06A61P31/02A61P15/00A61P15/02A61K31/045
CPCA61K31/045A61K9/0034A61K9/06A61K36/185A61K36/234A61K36/70A61K36/756A61K36/904A61K36/9066A61K47/32A61K47/36A61K47/38A61K2236/37A61K2236/39A61K2300/00
Inventor 黄陈国
Owner FUJIAN AINVREN BIOTECH CO LTD
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