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Medicine composition for treating reflux esophagitis and preparation method thereof

A technique for reflux esophagitis and a composition, applied in the field of medicine, can solve problems such as side effects and easy recurrence, and achieve the effects of fast curative effect, good therapeutic effect and short course of treatment

Inactive Publication Date: 2016-05-11
THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Western medicine mainly treats by inhibiting gastric acid secretion and improving gastric motility, such as domperidone (morphine), itopride, etc. H2 receptor antagonists or proton pump inhibitors can reduce gastric acid and protease secretion, but most of them can only Improve clinical symptoms, easy to relapse after drug withdrawal, long-term medication has certain side effects

Method used

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  • Medicine composition for treating reflux esophagitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0040] A pharmaceutical composition for treating reflux esophagitis, comprising the following raw materials in parts by weight:

[0041] Scutellaria barbata 600g, Angelica dahurica 700g, Tougucao 700g, Sanyu 800g, Heather vine 500g, Purslane 500g, Perilla 700g, Achyranthes 200g, Phytolacca 300g, Pterocarpus 20g, Geranium 60g;

[0042] It is prepared by the following method:

[0043] (1) Raw material pretreatment:

[0044] ①Pretreatment of dry raw materials: the sun-dried Chinese herbal medicine raw materials Scutellaria barbata, Angelica dahurica, Tougucao, Sanguis sylvestris, heather vine, hyssop, pokeweed to remove impurities and moldy parts, washed, dried, and broken up separately Fragments with a degree of 3~5cm;

[0045] ②Fresh raw material pretreatment: first rinse the fresh purslane and perilla with clean water, and then cut into pieces with a length of 1 to 2 cm;

[0046] (2) Decoction and filtration: mix the dry raw materials pretreated in step (1) according to the stated ratio...

Embodiment 2

[0051] A pharmaceutical composition for treating reflux esophagitis, comprising the following raw materials in parts by weight:

[0052] 8 parts of Scutellaria barbata, 6 parts of Angelica dahurica, 8 parts of Tougucao, 6 parts of Sanyu, 7 parts of Heather Vine, 7 parts of Purslane, 8 parts of Perilla, 3 parts of Achyranthes, 3 parts of Phytolacca, Pterocarpus 0.2 Parts, 0.8 parts of geraniol.

[0053] It is prepared by the following method:

[0054] (1) Raw material pretreatment:

[0055] ①Pretreatment of dry raw materials: the sun-dried Chinese herbal medicine raw materials Scutellaria barbata, Angelica dahurica, Tougucao, Sanguis sylvestris, heather vine, hyssop, pokeweed to remove impurities and moldy parts, washed, dried, and broken up separately Fragments with a degree of 3~5cm;

[0056] ②Fresh raw material pretreatment: first rinse the fresh purslane and perilla with clean water, and then cut into pieces with a length of 1 to 2 cm;

[0057] (2) Decoction and filtration: mix the ...

Embodiment 3

[0062] A pharmaceutical composition for treating reflux esophagitis, comprising the following raw materials in parts by weight:

[0063] 7 parts of Scutellaria barbata, 8 parts of Angelica dahuricae, 6 parts of Tougucao, 7 parts of Sanyu, 8 parts of Heather Vine, 8 parts of Purslane, 5 parts of Perilla, 2 parts of Achyranthes, 3 parts of Phytolacca, Pterocarpus 0.2 Parts, 0.5 parts of geraniol.

[0064] It is prepared by the following method:

[0065] (1) Raw material pretreatment:

[0066] ①Pretreatment of dry raw materials: the sun-dried Chinese herbal medicine raw materials Scutellaria barbata, Angelica dahurica, Tougucao, Sanguis sylvestris, heather vine, hyssop, pokeweed to remove impurities and moldy parts, washed, dried, and broken up separately Fragments with a degree of 3~5cm;

[0067] ②Fresh raw material pretreatment: first rinse the fresh purslane and perilla with clean water, and then cut into pieces with a length of 1 to 2 cm;

[0068] (2) Decoction and filtration: mix the...

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Abstract

The invention discloses a medicine composition for treating reflux esophagitis and a preparation method thereof. The medicine composition is prepared from, by weight, 5-10 parts of herba scutellariaebarbatae, 5-10 parts of radix angelicae dahuricae, 5-10 parts of tuberculate speranskia herbs, 5-10 parts of sanguisorba roots, 5-10 parts of caulis erycibes, 5-10 parts of herba portulacae, 5-10 parts of folium perillae, 2-5 parts of radix achyranthis bidentatae, 2-5 parts of radix phytolaccae, 0.1-0.3 part of pterostilbene and 0.1-1 part of diosmetin. The medicine composition can quiet the heart, tonify the spleen, invigorate blood circulation, remove blood stasis, calm the adverse-rising energy, control nausea and vomiting, soothe the liver, regulate vital energy, eliminate cold to stop pain, remove stasis to eliminate lumps, relieve hyperacidity and reduce adverse-rising energy, can obviously improve such symptoms as heartburning, sour regurgitation, substernal burning discomfort or causalgia and dysphagia, has an extremely good treatment effect on reflux esophagitis and is short in treatment course, quick in effectiveness and free of side effects on the human body.

Description

Technical field [0001] The invention relates to a pharmaceutical composition for treating reflux esophagitis and a preparation method thereof, and belongs to the technical field of medicine. Background technique [0002] Reflux esophagitis (refluxesophagitis, RE) is a gastroesophageal reflux disease, which refers to the peptic inflammation, erosion, and ulcer of the esophageal mucosa caused by the reflux of the contents of the stomach and duodenum into the esophagus. It is the defense of the esophagus As a result of the combined effect of mechanism decline and gastric reflux, the main symptoms are heartburn, acid reflux, post-sternal burning discomfort or burning pain, and syndromes such as dysphagia. If there is no systemic treatment for a long time or the patients who cannot completely control their symptoms, they will have esophageal stenosis, ulcers, upper gastrointestinal bleeding, and severe esophageal cancer can progress. Western countries have a high incidence rate, whil...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/739A61P1/04A61K31/09A61K31/352
CPCA61K36/739A61K31/09A61K31/352A61K36/185A61K36/21A61K36/232A61K36/47A61K36/535A61K36/539A61K36/67A61K2236/331A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 荆伟丽赵振寰傅蓉孙雪梅毛桂杰
Owner THE AFFILIATED HOSPITAL OF QINGDAO UNIV
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