Medical alginate dressing and preparation method thereof

A technology of alginate and citric acid, which is applied in the field of medical materials, can solve the problems of bacterial growth, slow wound healing, and lower moisture retention, and achieve good antibacterial effect and improve relative moisture retention

Inactive Publication Date: 2016-06-22
SUZHOU BEC BIOLOGICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] During the use of the dressing, as time goes by, the moisture retention decreases, and the wound healing speed slows down. At the same time, due to the complex environment, it is easy to cause bacteria to grow

Method used

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  • Medical alginate dressing and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A medical alginate dressing, consisting of the following components by mass: 56 parts of sodium alginate, 5 parts of sodium pyrophosphate, 1 part of sodium carboxymethylcellulose, 3 parts of citric acid, 12 parts of polyvinyl alcohol, Ginger extract 4 parts, mannitol 5 parts, hyaluronic acid 7 parts.

[0018] Preparation:

[0019] (1) According to the above mass parts, mix sodium alginate, sodium pyrophosphate, sodium carboxymethylcellulose, citric acid, polyvinyl alcohol, ginger extract, mannitol and hyaluronic acid, and obtain the mixture after ultrasonication at 50°C for 10 minutes one;

[0020] (2) Cool the mixture 1 obtained in step (1), then place in a stirrer and add hydrochloric acid dropwise until the pH is 5-6, and mix well to obtain mixture 2;

[0021] (3) Soak the degreasing gauze in the mixture 2 obtained in step (2), place it in a dryer to dry, seal, pack, and obtain it after ultraviolet sterilization, wherein the soaking time is 30min, and the temperatu...

Embodiment 2

[0023] A medical alginate dressing, consisting of the following components by mass: 69 parts of calcium alginate, 18 parts of sodium pyrophosphate, 15 parts of sodium carboxymethylcellulose, 12 parts of citric acid, 23 parts of polyvinyl alcohol, 17 parts of ginger extract, 14 parts of mannitol, and 19 parts of hyaluronic acid.

[0024] Preparation:

[0025] (1) According to the above mass parts, calcium alginate, sodium pyrophosphate, sodium carboxymethylcellulose, citric acid, polyvinyl alcohol, ginger extract, mannitol and hyaluronic acid were mixed, and the mixture was obtained after ultrasonication at 75°C for 25 minutes one;

[0026] (2) Cool the mixture 1 obtained in step (1), then place in a stirrer and add hydrochloric acid dropwise until the pH is 5-6, and mix well to obtain mixture 2;

[0027] (3) Soak the degreased gauze in the mixture 2 obtained in step (2), place it in a dryer to dry, seal, pack, and get it after ultraviolet sterilization, wherein the soaking t...

Embodiment 3

[0029] A medical alginate dressing, consisting of the following components by mass: 59 parts of sodium alginate, 8 parts of sodium pyrophosphate, 5 parts of sodium carboxymethylcellulose, 4 parts of citric acid, 17 parts of polyvinyl alcohol, Ginger extract 8 parts, mannitol 9 parts, hyaluronic acid 10 parts.

[0030] Preparation:

[0031] (1) According to the above mass parts, mix sodium alginate, sodium pyrophosphate, sodium carboxymethylcellulose, citric acid, polyvinyl alcohol, ginger extract, mannitol and hyaluronic acid, and obtain the mixture after ultrasonication at 55°C for 15 minutes one;

[0032] (2) Cool the mixture 1 obtained in step (1), then place in a stirrer and add hydrochloric acid dropwise until the pH is 5-6, and mix well to obtain mixture 2;

[0033] (3) Soak the degreased gauze in the mixture 2 obtained in step (2), place it in a dryer to dry, seal, pack, and get it after ultraviolet sterilization, wherein the soaking time is 35min, and the temperature...

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Abstract

The invention discloses a medical alginate dressing and a preparation method thereof. The dressing is prepared from components in parts by mass as follows: 56-69 parts of alginate, 5-18 parts of sodium pyrophosphate, 1-15 parts of sodium carboxymethylcellulose, 3-12 parts of citric acid, 12-23 parts of polyvinyl alcohol, 4-17 parts of a ginger extract, 5-14 parts of mannitol and 7-19 parts of hyaluronic acid. The relative moisture retention property of the prepared dressing is improved under the synergistic effect of the components, and meanwhile, Staphylococcus aureus and Citrobacter do not grow, so that the dressing has the good anti-bacterial effect and can be widely applied to clinical treatment.

Description

technical field [0001] The invention belongs to the field of medical materials, and in particular relates to a medical alginate dressing and a preparation method thereof. Background technique [0002] Dressing refers to the auxiliary materials used in addition to the main material of the article. An important function of modern wound dressing is that it replaces the important function of damaged skin and continues to heal the wound and skin lesions. It protects against mechanical factors (e.g. dirt, impact, inflammation, etc.), against pollution and chemical stimuli; against secondary infection; against desiccation and loss of body fluids (electrolyte loss); against heat loss; actively affects the wound healing process through debridement, Create a microenvironment that promotes wound healing. [0003] During the use of dressings, as time goes by, the moisture retention decreases, and the wound healing speed slows down. At the same time, due to the complex environment, it i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/28A61L15/18A61L15/20A61L15/24A61L15/44
CPCA61L15/28A61L15/18A61L15/20A61L15/24A61L15/44A61L2300/30A61L2300/404C08L5/04C08L1/08C08L29/04
Inventor 李苏杨李文遐徐勤霞
Owner SUZHOU BEC BIOLOGICAL TECH
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