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A detection method and device based on magnocellular visual pathway function

A visual pathway and detection device technology, applied in the field of visual cognition and detection, to achieve the effect of simple and easy operation, clear and definite results, and strong acceptability

Active Publication Date: 2018-07-10
EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

In addition to frequency-doubling visual field, motion visual field is another detection method that is considered to detect the function of magnocellular visual pathway. The most commonly used is the random point motion map test, but scholars point out that this kind of judgment of the consistent direction of random point motion Relying on the spatial integration in a larger area of ​​the visual field, the scope of this integrated area is significantly larger than the receptive field of large ganglion cells, and closer to the receptive field of neurons in the higher visual cortex (such as MT / V5 area), indicating that this functional detection is relatively difficult. Higher motor cortex function without large and small cell specificity in this area

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  • A detection method and device based on magnocellular visual pathway function
  • A detection method and device based on magnocellular visual pathway function
  • A detection method and device based on magnocellular visual pathway function

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Experimental program
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Embodiment 1

[0049] Visual stimulation was given to the subjects through the visual presentation system, and the corresponding results were obtained by observing the feedback of the subjects.

[0050] hardware equipment:

[0051] Test hardware system of the present invention is made of Macbook Pro connecting high-precision display screen (CRT) and external keyboard; Load computer language Matlab and psychotoolbox toolkit in computer operating system; Display screen resolution is not less than 1024 * 768, refresh rate is 60; Before the test, the display screen needs to be gamma corrected with a luminance meter.

[0052] Visual stimulus:

[0053] Visual stimuli are mainly red-green square-wave bars of equal brightness (such as figure 1 shown); the spatial frequency of the red-green grid is 2.5 cycles / degree, the phase of the red and green grids alternates every 500ms to prevent adaptation, and the brightness of the same position of the red and green grids has a spatial frequency of 0.5 cyc...

Embodiment 2

[0062] Embodiment 2 method verifies the selectivity of the present invention to measuring magnocellular visual pathway function

[0063] In this example, glaucoma patients before standard visual field damage were selected as the verification objects, and it was theoretically supported that the large cell pathway function of glaucoma patients was first damaged or the damage was more serious, that is, the "large cell pathway selective damage hypothesis"; 30 patients before standard visual field damage were included. Patients with primary open-angle glaucoma and 30 normal controls matched in age, sex, and refractive state verified the present invention. Sign the informed consent form.

[0064] In the verification process, two time-frequency conditions were added, that is, four time-frequency conditions were shared: 3 Hz, 8 Hz, 15 Hz, and 25 Hz, with the time frequency as the abscissa and the contrast sensitivity as the ordinate, the results of the two groups were Both are "inver...

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Abstract

The invention belongs to the technical field of visual cognition and detection, and relates to a detection method and a device based on the function of the large cell visual pathway. Since the small cell pathway is mainly activated by color information, its resolution to weaker additional brightness information changes is small, and the brightness information is mainly mediated by the large cell visual pathway, thereby selectively measuring the function of the large cell visual pathway; through detection Experiments show that the contrast sensitivity result extracted in the present invention is mainly the response mediated by the magnocellular visual pathway; it has selectivity for measuring the function of the magnocellular visual pathway, and has high sensitivity performance. The operation of the invention is simple and easy, the result is clear and definite, and the user acceptability is strong, and can be used for preparing visual function evaluation standards related to magnocellular pathways.

Description

technical field [0001] The invention belongs to the technical field of visual cognition and detection, and relates to a detection method and a device based on the visual pathway function of large cells, in particular to a visual psychophysical detection method based on the visual pathway function of living large cells. The method can selectively extract and quantify the function of the magnocellular visual pathway by using visual psychophysics technology, and further be used to prepare visual function evaluation standards related to the magnocellular pathway. Background technique [0002] The prior art discloses that parallel signal transduction pathways are one of the important features of the mammalian sensory system, and relatively parallel large and small cell pathways also exist in the most important visual perception system in the sensory system. Studies have shown that the large and small cell pathways remain relatively separated in structure: that is, the small cell ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61B3/02
Inventor 孙兴怀何生文雯
Owner EYE & ENT HOSPITAL SHANGHAI MEDICAL SCHOOL FUDAN UNIV