Traditional Chinese medicine for treating heart-kidney imbalance craniocerebral trauma syndrome and preparation method

A technology for brain trauma, heart-kidney disharmony, applied in medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as unsatisfactory curative effects, eliminate adverse reactions, have no toxic side effects, and improve treatment effect of effect

Inactive Publication Date: 2016-10-12
程相标
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, craniocerebral trauma syndrome is one of the clinical refractory diseases. At present, psychotherapy is the main treatment. In addition, Western medicine or Chinese patent medicines are given brain metabolism drugs and autonomic nervous function regulation drugs, analgesia, sedation and symptomatic treatment. treatment, but the effect is not satisfactory

Method used

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Examples

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Effect test

preparation example Construction

[0038] The present invention also provides a preparation method of the above-mentioned Chinese medicine, wherein the dosage form of the Chinese medicine is granule, and the preparation method comprises the following steps:

[0039] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 85% to 95% relative to the mixture 4 to 8 times, heat to boiling and reflux for 3 to 5 hours, filter, and use the reflux liquid as a solvent , using the filter residue as the solute, use the percolation method to slowly percolate at a rate of 1-2ml per minute, collect the percolation liquid, and then concentrate it under reduced pressure at a vacuum of 0.06-0.09Mpa to 50-60°C with a relative density of 1.04 ~1.10 paste, spray drying, the air inlet temperature of the spray dryer is 160~175℃, and the air outlet temperature is 80~85℃, and then crushed into powder to make dry paste powder;

[0040] Step 2: Add 0.2-0.4 times of sucrose powd...

Embodiment 1

[0046] Embodiment 1: Granules

[0047] Take 160g of Yiyi, 210g of Centipede vine, 290g of green arrow, 160g of pigudan, 90g of wolfgrass, 260g of Qinglanggan, 140g of square vine, 280g of calendula, 200g of white residual flower, 180g of tree onion, 160g of mountain leek, rock lettuce 140g, 220g chicken shell, 150g fake pigeonpea and 260g mao.

[0048] Prepare as follows:

[0049] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration of 90% which is 7 times that of the mixture, heat to boiling and reflux for 4 hours, filter, use the reflux liquid as the solvent, and use the filter residue as the solute. The percolation method slowly percolates at a speed of 2ml per minute, collects the percolation liquid, and then concentrates it under reduced pressure at a vacuum of 0.07Mpa to a paste with a relative density of 1.08 at 55°C, sprays and dries, and the air inlet of the spray dryer The temperature is 170°C, the air out...

Embodiment 2

[0051] Embodiment 2: capsules

[0052] Take 190g of Yiyi, 180g of Centipede vine, 320g of green arrow, 140g of pigudan, 120g of wolfgrass, 230g of qinglanggan, 170g of square vine, 260g of calendula, 240g of white residual flower, 160g of tree onion, 200g of mountain leek, rock lettuce 110g, 250g chicken shell, 120g fake pigeonpea and 300g mao;

[0053] Prepare as follows:

[0054] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 90% that is 4 times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and the second extract, and concentrate under reduced pressure to remove Ethanol solvent, drying, obtains dry paste;

...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating a heart-kidney imbalance craniocerebral trauma syndrome and a preparation method. The traditional Chinese medicine comprises the following raw herbal materials: fructus docynia delavayi schneid, pothos repens, herb of drooping clinacanthus, leaf of common gendarussa, bur beggarticks herb, malachite, cissus pteroclada hayata, potmarigold calendula flower and root, flower of Japanese rose, herb of digitateleaf eria, wallich garlic herb, all-grass of cliff briggsia, eggshell, herba seu radix desmodii triangularis and radix seu folium melastomatis sanhuinei . The invention has the beneficial effects that the traditional Chinese medicine provided by the invention can be combined with a conventional western medicine to treating the heart-kidney imbalanc ecraniocerebral trauma syndrome, so that the treatment effect of the western medicine is effectively improved without toxic and side effects, and the untoward effects of the western medicine are reduced or eliminated.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating heart-kidney disharmony type craniocerebral trauma syndrome and a preparation method thereof. Background technique [0002] Traumatic brain injury syndrome is very common after craniocerebral injury, and about 20% of patients will leave some neurological or mental obstacles after injury. The disease includes cerebral cortex dysfunction, cerebral cortex excitation and inhibition process disorder, autonomic nervous system dysfunction and so on. Traumatic brain injury is a critical illness with a high mortality rate in the acute phase. Although most patients get better after treatment, they are prone to sequelae, which brings a lot of inconvenience to the study and life of the patients after the illness. Traumatic brain injury syndrome refers to a series of physical and emotional sympt...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/898A61K9/16A61K9/48A61P25/00A61K35/614A61K35/57
CPCA61K9/1652A61K9/4858A61K35/57A61K35/614A61K36/185A61K36/19A61K36/28A61K36/48A61K36/73A61K36/738A61K36/87A61K36/888A61K36/8962A61K36/898A61K2236/333A61K2236/51A61K2300/00
Inventor 程相标周茂军徐国成
Owner 程相标
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