Traditional Chinese medicine for treating gout and hyperuricemia and preparation method thereof

A technology of hyperuricemia and traditional Chinese medicine, which is applied in the direction of medical formulas, medical preparations containing active ingredients, drug combinations, etc., can solve problems such as side effects, fulminant hepatitis, bone marrow toxic allergies, etc., and achieve small toxic and side effects, reduce The level of uric acid and urea nitrogen in blood and urine, and the effect of reducing the level of uric acid and urea nitrogen

Active Publication Date: 2020-02-14
于翔
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although these drugs have a certain therapeutic effect, they are also accompanied by side effects of varying degrees during the treatment process, such as vomiting, fulminant hepatitis, bone marrow toxicity allergy, etc., which seriously affect the health of patients. Therefore, active development and introduction of curative effects Anti-gout products with significant side effects and few side effects are still the direction of many medical workers’ efforts

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0035] A traditional Chinese medicine for treating gout and hyperuricemia, which is made from the following raw materials according to the stated parts by weight: 40 parts of Coptis chinensis, 40 parts of Evodia rutaecarpa, 14 parts of Motherwort, 50 parts of Corydalis Corydalis, 70 parts of Bamboo Leaf, Coix Seed 20 servings.

[0036] Its preparation method is as follows:

[0037] (1) Preparation of Coptis chinensis extract: Wash, dry, crush and sieve Coptis chinensis medicinal materials meeting the stated weight parts, add 85% ethanol to reflux extraction twice, each time for 1.5 hours, collect the extract, and then extract the above The dregs are extracted twice with water and reflux, the extracts are collected, the two extracts are combined, filtered, the filtrate is concentrated, the concentrate is adsorbed with styrene-type weak polarity or non-polar macroporous resin, and the column is washed with ethanol solutions of different concentrations in sequence Elution, the e...

Embodiment 2

[0045] A traditional Chinese medicine for treating gout and hyperuricemia, which is made of the following raw materials according to the stated parts by weight: 15 parts of Coptis chinensis, 8.5 parts of Evodia rutaecarpa, 15 parts of Motherwort, 100 parts of Corydalis Corydalis, 18 parts of Bamboo Leaf, Coix Seed 6 servings.

[0046] Its preparation method is as follows:

[0047] (1) Preparation of Coptis chinensis extract: Wash, dry, crush and sieve Coptis chinensis medicinal materials that meet the stated weight parts, add 80% ethanol for reflux extraction twice, each time for 1 hour, collect the extract, and then extract the above The dregs are extracted twice with water and reflux, the extracts are collected, the two extracts are combined, filtered, the filtrate is concentrated, the concentrate is adsorbed with styrene-type weak polarity or non-polar macroporous resin, and the column is washed with ethanol solutions of different concentrations in sequence Elution, the el...

Embodiment 3

[0055] A traditional Chinese medicine for treating gout and hyperuricemia, which is made from the following raw materials according to the stated parts by weight: 60 parts of Coptis chinensis, 20 parts of Evodia rutaecarpa, 60 parts of Motherwort, 450 parts of Corydalis Corydalis, 100 parts of Bamboo Leaf, Coix Seed 50 servings.

[0056] Its preparation method is as follows:

[0057] (1) Preparation of Coptis chinensis extract: Wash, dry, pulverize and sieve Coptis chinensis medicinal materials that meet the stated weight parts, add 90% ethanol to reflux for extraction twice, each time for 2 hours, collect the extract, and then extract the above The dregs are extracted twice with water and reflux, the extracts are collected, the two extracts are combined, filtered, the filtrate is concentrated, the concentrate is adsorbed with styrene-type weak polarity or non-polar macroporous resin, and the column is washed with ethanol solutions of different concentrations in sequence Elut...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine, and particularly relates to a traditional Chinese medicine for treating gout and hyperuricemia and a preparing method thereof. The traditional Chinese medicine is composed of active components or active components and pharmaceutically acceptable auxiliary materials, wherein the active components are extracted from, by weight, 15-135 parts of coptidis rhizome, 8.5-76 parts of fructus evodiae, 14-130 parts of herba leonuri, 50-900 parts of rhizoma corydalis, 18-158 parts of common lophatherum herb and 6-114 parts of semen coicis. The traditional Chinese medicine can dispel wind and eliminate dampness, relieve swelling and pain, and remarkably reduce the level of uric acid and urea nitrogen of gout patients, has an obvious treatment effect on gout and hyperuricemia, and is free of toxic or side effect. The traditional Chinese medicine can be used for treating arthritis, rheumatoid arthritis, gout and limb joint arthrocele, pain and dysarthrasis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine for treating gout and hyperuricemia, which belongs to the technical field of traditional Chinese medicines. Background technique [0002] Gout is a group of metabolic diseases caused by excessive production of uric acid, decreased excretion of uric acid, and accumulation of precipitates in the body due to purine metabolic disorders. Gout must be accompanied by hyperuricemia, hyperuricemia is the premise and biochemical basis of gout. Clinically, recurrent gouty acute arthritis, tophi deposition, characteristic chronic arthritis, and joint deformities are common, and kidneys are often involved, causing chronic interstitial nephritis and renal uric acid stones. [0003] With the improvement of people's living standards and changes in dietary structure, excessive intake of high-purine foods has led to an increasing trend in the incidence of hyperuricemia and gout worldwide. The data shows that the ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8994A61P19/06A61P19/02
CPCA61K36/533A61K36/66A61K36/718A61K36/754A61K36/899A61K36/8994A61K2236/331A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 于翔
Owner 于翔
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