DIPA compounds as local reagents applied to treatment of sensory discomfort
What is Al technical title?
Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A propylphosphonoheptane, topical technology for use in the field of therapeutic compounds
Inactive Publication Date: 2016-11-23
奥云达药业
View PDF3 Cites 1 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
No biological activity of this diisop...
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment approach 1
[0030] Embodiment 1: A therapeutic product comprising a compound of Formula 1 and a delivery vehicle carrying the compound of Formula 1 in said therapeutic product:
[0031]
[0032] Wherein, R is n-pentyl, n-hexyl, n-heptyl, and / or n-nonyl;
[0033] The delivery vehicle is suitable for topical delivery.
Embodiment approach 2
[0034] Embodiment 2: The therapeutic article of Embodiment 1, wherein the compound is 1-diisopropylphosphonopentane.
Embodiment approach 3
[0035] Embodiment 3: The therapeutic article of Embodiment 1, wherein the compound is 1-diisopropylphosphonohexane.
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention provides DIPA compounds as local reagents applied to treatment of sensory discomfort and generally relates to the field of therapeutic compounds. More particularly, the invention relates to certain DIPA compounds collectively known as DIPA-1-5, DIPA-1-6, DIPA-1-7, DIPA-1-8 and DIPA-1-9 in the specification. The DIPA compounds can be applied to treatment of symptoms such as sensory discomfort, skin dysesthesia, dermatitis, eye pain and discomfort, heat discomfort, heat stress, blush and/or night sweat, postoperative hypothermia, postanesthesia shivering, fatigue, tiredness, depression and cognitive dysfunction, and can be used for enhancing the cognitive function.
Description
technical field [0001] The present invention relates generally to the field of therapeutic compounds. More specifically, the present invention relates to certain diisopropylphosphonoalkanes (DIPA-1-5, DIPA-1-6, DIPA-1-7, collectively referred to herein as "DIPA compounds") as described herein. , DIPA-1-8, and DIPA-1-9), these diisopropylphosphonoalkanes are useful, for example, in the treatment of disorders (e.g., diseases) that include: sensory discomfort (e.g., caused by irritation, itching, or pain ), skin dysesthesia, atopic dermatitis, ocular pain and discomfort, thermal malaise, heat stress, flushing and / or night sweats (vasomotor symptoms), postoperative hypothermia, postanesthesia rigors, fatigue, exhaustion, Depression, cognitive impairment, and may be used to enhance cognitive function. The invention also relates to pharmaceutical compositions comprising such compounds, and to the use of such compounds and compositions, for example in therapy, diagnosis, and labora...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.