Fast dissolving granulate
A granular and rapid technology, applied in the direction of medical preparations containing active ingredients, block delivery, plant raw materials, etc., can solve the problems of disgusting smell and taste, ether oil that loses essence, etc.
Inactive Publication Date: 2016-12-14
BOEHRINGER INGELHEIM INT GMBH
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- Abstract
- Description
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- Application Information
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Problems solved by technology
[0005] However, such pellets lose essential ether oils due to evaporation and have a nasty smell and taste
Method used
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Embodiment A1
[0049]
[0050]
Embodiment A2
[0052] components
Embodiment A3
[0054] components
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The invention relates to a fast dissolving granulate obtainable by spray-dying of a composition comprising a dry methanolic or ethanolic extract of valerian root, a dry methanolic extract of hop strobiles, optionally a carrier, one or more artificial sweeteners, one or more flavoring agents, optionally an acidifier and water for the treatment of sleep disorders, wherein the said granulate is to be administered upon dissolution in water or an aqueous beverage shortly before bedtime.
Description
technical field [0001] The present invention relates to a rapidly dissolving granule for use in the treatment of sleep disorders comprising: a spray-dried methanolic or ethanol extract of valerian root, a spray-dried methanolic extract of hops spore bulbs, one or more artificial Sweetener, one or more flavoring agents. Background technique [0002] Valerian and hop extracts are natural active ingredients widely used to treat sleep disorders. The evaluation report of the European Medicines Agency (EMA) on "Valeriana officinalis L., radix and Humulus lupulus L., flos" (EMA / HMPC / 215214 / 2008 of May 6, 2010) confirmed the feasibility and effective use of Coated tablets of methanolic or ethanol extracts of valerian root and methanolic extracts of dried hops spore bulbs for the treatment of mild sleep disturbances and / or catatonic sleep. [0003] Many patients with mild sleep disturbances are more likely to drink a drink that improves their sleep disturbance than to take a pill. ...
Claims
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IPC IPC(8): A61K36/84A61K9/16A61P25/20A61K125/00
CPCA61K9/1623A61K36/60A61K36/84A61K2300/00A61K36/185A61K9/0095A61P25/20
Inventor B·普洛曼U·朔伊林
Owner BOEHRINGER INGELHEIM INT GMBH
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