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A kind of pharmaceutical composition for treating schizophrenia and its application

A technology for schizophrenia and a composition, which is applied in the field of medicine and achieves the effects of good curative effect, high safety, and improvement of clinical symptoms

Active Publication Date: 2019-11-12
SHANGHAI MENTAL HEALTH CENT (SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENT)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, in the prior art, there is no report about the pharmaceutical composition for the treatment of schizophrenia of the present invention.

Method used

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  • A kind of pharmaceutical composition for treating schizophrenia and its application
  • A kind of pharmaceutical composition for treating schizophrenia and its application
  • A kind of pharmaceutical composition for treating schizophrenia and its application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 The preparation of the present invention's medicine for treating schizophrenia (1)

[0025] Raw materials are configured in proportion: zedoary oil 2.5ml, red peony root 1000g, raw rhubarb 1000g.

Embodiment 2

[0026] Embodiment 2 The preparation of the present invention's medicine for treating schizophrenia (two)

[0027] Raw materials are configured in proportion: zedoary oil 1ml, red peony root 500g, raw rhubarb 500g.

Embodiment 3

[0028] Embodiment 3 The preparation of the medicine for treating schizophrenia of the present invention (three)

[0029] Raw materials are configured in proportion: zedoary oil 5ml, red peony root 1000g, raw rhubarb 1000g.

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PUM

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Abstract

The invention relates to a medicine composition for treating schizophrenia. The medicine composition is prepared from the following raw materials in parts by weight: 1-5 parts of zedoary turmeric oil, 500-1000 parts of radix paeoniae rubra and 500-1000 parts of raw rhubarb. The medicine composition can be combined with risperidone for treating patients with schizophrenia and effectively improving the clinical symptoms of the patients, especially the field of negative symptoms, and has a remarkable curative effect superior to that of a placebo group; and in the aspect of adverse response, the occurrence rate of the medicine composition in the aspects of constipation, thirst and weight increase is far lower than those of the placebo group. The medicine has a remarkable curative effect on schizophrenia patients with predominantly negative symptoms, has high safety, and is worthy of clinical popularization and application.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a pharmaceutical composition for treating schizophrenia and its application. Background technique [0002] American psychiatrist Crow proposed in the 1980s that schizophrenia can be divided into positive symptoms and negative symptoms. Negative symptoms mainly manifest as lack of thinking, apathy, and laziness in life, and most patients have a poor prognosis. In the category of traditional Chinese medicine, schizophrenia mostly belongs to "epilepsy" and "madness". Epilepsy in traditional Chinese medicine belongs to Yin syndrome, characterized by indifferent expression, silent dementia, quietness and inactivity, and is basically the same as schizophrenia in Western medicine, which is dominated by negative symptoms. And Chinese medicine believes that the occurrence of mental illness is closely related to "blood storage" and "qi and blood stagnation", which makes the brain qi and...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/519A61K36/9066A61P25/18
CPCA61K31/519A61K36/65A61K36/708A61K36/71A61K36/9066A61K2300/00
Inventor 朱丽萍张建明陈美娟龙彬陈妍吴海苏赵敏卢卫红
Owner SHANGHAI MENTAL HEALTH CENT (SHANGHAI PSYCHOLOGICAL COUNSELLING TRAINING CENT)