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A kind of chiral metal-organic nanocrystal sensor and its preparation method and application

A metal-organic and nanocrystalline technology, which is applied in instruments, scientific instruments, and material analysis through electromagnetic means, can solve the problems of long analysis time, high instrument cost, difficulty in in-situ and online detection, etc., and achieve simple detection operation , The preparation method is simple and easy to operate

Inactive Publication Date: 2019-02-19
UNIV OF JINAN
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, chromatography has been widely used to separate and analyze chiral compounds, but this method has certain shortcomings, such as high instrument cost, long analysis time, and it is particularly difficult to realize in-situ and online detection, etc.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] 0.2mmol of Ce(NO 3 ) 3 ·6H 2 O dissolved in 4 mL of water; 0.3 mmol of D-(+)-camphoric acid H 2 Cam and 0.2 mmol of terephthalic acid H 2 Bdc was dissolved in 3 mL of DMF; the two solutions were blended at room temperature to obtain a clear mixed solution; 0.2 mL of 10% NaOH ethanol solution was added dropwise in 10 s and shaken and blended to obtain a chiral metal-organic complex After washing it, the obtained solid powder was dried overnight at 105-110° C. to obtain chiral metal-organic nanocrystals with a yield of 60%;

Embodiment 2

[0031] 0.2mmol of Ce(NO 3 ) 3 ·6H 2 O dissolved in 4 mL of water; 0.4 mmol of D-(+)-camphoric acid H 2 Cam and 0.3 mmol of terephthalic acid H 2 Bdc was dissolved in 5 mL of DMF; the two solutions were blended at room temperature to obtain a clear mixed solution; 0.5 mL of 10% NaOH ethanol solution was added dropwise in 30 s and shaken and blended to obtain a chiral metal-organic complex After washing it, the obtained solid powder was dried overnight at 105-110° C. to obtain chiral metal-organic nanocrystals with a yield of 65%;

Embodiment 3

[0033] 0.2mmol of Ce(NO 3 ) 3 ·6H 2 O dissolved in 4 mL of water; 0.35 mmol of D-(+)-camphoric acid H 2 Cam and 0.25 mmol of terephthalic acid H 2Bdc was dissolved in 4 mL of DMF; the two solutions were blended at room temperature to obtain a clear mixed solution; 0.35 mL of NaOH ethanol solution with a mass fraction of 10% was added dropwise in 20 s and shaken and blended to obtain a chiral metal-organic complex After washing, the obtained solid powder was dried overnight at 105-110° C. to obtain chiral metal-organic nanocrystals with a yield of 62%;

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Abstract

The invention relates to a chiral metal organic nanocrystalline sensor and belongs to the technical field of metal organic nanocrystalline complexes and chiral sensing detection. Ce(NO3)3.6H2O, D-(+)-camphanic acid and terephthalic acid serve as raw materials, chiral metal organic complex gel is prepared first, and then chiral metal organic nanocrystalline is prepared. The preparing method is easy and convenient to implement and low in energy consumption. The electrochemical chiral sensor prepared with the nanocrystalline is quick in response, good in selectivity and high in flexibility when used for detecting the contents of D-(+)-tryptophan and L-(-)-tryptophan chiral enantiomers.

Description

technical field [0001] The invention discloses a chiral metal-organic nanocrystal and its preparation method and application, and belongs to the technical field of nano functional materials, metal organic complex nanomaterials and chiral sensing and detection. Background technique [0002] Chirality is a common phenomenon in nature and one of the essential attributes that human beings rely on for survival. Various biochemical reaction processes that occur in the course of life are closely related to chiral recognition and changes. In recent years, people's understanding of chiral issues and Research has moved from pure molecular chirality to more diverse supramolecular chirality and other chiral research fields above the molecular level. In addition to the ubiquitous chiral assembly phenomenon in nature, a wide variety of chiral assembly structures with diverse functions can be constructed through artificial design. [0003] Chiral assembly refers to the combination of chir...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G01N27/26G01N27/30G01N27/32
CPCG01N27/26G01N27/30G01N27/301G01N27/32
Inventor 匡轩闫涛孙旭张勇王欢王雪莹魏琴王志玲
Owner UNIV OF JINAN