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Composition for treating cancers and preparations and application thereof

A compound and cancer technology, applied in the direction of medical preparations, drug combinations, organic active ingredients, etc. , There are no issues such as the therapeutic use of the undisclosed compound, to achieve the effect of improving the therapeutic effect, low side effects, and reducing the occurrence and development

Active Publication Date: 2017-02-22
普罗布诺(重庆)生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The prior art discloses many complexes containing antimalarial drugs for the treatment of cancer, but the prior art does not disclose complexes composed of artemisinin antimalarials and aminoquinoline antimalarials, nor No therapeutic use of this complex has been disclosed

Method used

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  • Composition for treating cancers and preparations and application thereof
  • Composition for treating cancers and preparations and application thereof
  • Composition for treating cancers and preparations and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0051] Embodiment 1 A compound for treating cancer

[0052] The complex includes artemisinin and chloroquine, and the molar ratio of artemisinin and chloroquine is 0.1:100.

Embodiment 2

[0053] Embodiment 2 A compound for treating cancer

[0054] The complex includes artemisinin and chloroquine, and the molar ratio of artemisinin and chloroquine is 100:0.1.

Embodiment 3

[0055] Embodiment 3 A compound for treating cancer

[0056] The complex includes artemisinin and chloroquine, and the molar ratio of artemisinin and chloroquine is 1:1.

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Abstract

The invention provides a composition prepared from artemisinin antimalarials and aminoquinoline antimalarials; the composition is suitable for treating the cancers, such as lung cancer, breast cancer and melanoma, has low side effect, and is effective in improving cancer treatment effect and reducing the development and progress of a patient's complications.

Description

technical field [0001] The invention belongs to the field of pharmaceutical preparations containing organic active ingredients, and in particular relates to a compound for treating cancer and its preparation and application. Background technique [0002] Cancer is one of the most important diseases threatening human health, and its publication rate is increasing year by year. Among them, lung cancer and breast cancer are the most common malignant tumors. The current main treatment for cancer is chemotherapy. There are many anticancer drugs on the market, including alkylating agents, antimetabolites, and antitumor antibiotics, but most of these drugs are not tolerated by patients due to their high toxicity. With the continuous development of science and technology, the continuous change of lifestyle, and the rising incidence and mortality of cancer, it is imminent to study drugs for the treatment of cancer. [0003] Artemisinin is a sesquiterpene lactone isolated from the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/4706A61K31/366A61K31/357A61K31/496A61P35/00
CPCA61K31/357A61K31/366A61K31/4706A61K45/06A61P35/00A61K2300/00
Inventor 饶栓
Owner 普罗布诺(重庆)生物技术有限公司
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