Acanthopanacis senticosi radix et rhizoma seu caulis and herba hedyotis diffusae capsule and application thereof to treatment of leukopenia
A technology of Acanthopanax and Hedyotis diffusa, applied in capsule delivery, extracellular fluid diseases, medical preparations containing active ingredients, etc., can solve the problem of strong toxicity, low potency of sulfur-containing radiation prevention drugs, long-term Problems such as side effects are not easy to overcome
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Embodiment 1
[0059] Embodiment 1, the preparation of thorn white capsule
[0060] The formula of Cibai jiaonang of the present invention (Cibai jiaonang) is as follows: Acanthopanax 200g, Hedyotis diffusa 300g, Dodder 150g, Psoralen 150g, Angelica 150g, Astragalus 200g, Chishao 100g, Rehmannia glutinosa 150g, Lycium barbarum 150g, Spatholobus 150g. The specific preparation method is as follows:
[0061] 1. Add 200g Acanthopanax 200g and add water to decoct twice, add 8 times the amount of water each time, 3 hours each time, combine the decoction, filter, concentrate the filtrate into extract, and obtain Acanthopanax extract;
[0062] 2. Add 150g of dodder, 150g of psoralen, 150g of spatholobus and 300g of Hedyotis diffusa to reflux three times with 75% ethanol aqueous solution, 8 times the amount of 75% ethanol aqueous solution for 2 hours each time, and combine the ethanol extracts, Filtrate, recover the ethanol from the filtrate under reduced pressure until there is no alcohol smell, a...
Embodiment 2
[0065] Example 2, the application of Libai Capsules in the treatment of leukopenia caused by low-dose radiation
[0066] The present invention observes the effect of thorn white capsule on 1.0Gy 60 The effects of Coγ-ray whole-body irradiation on peripheral blood leukocytes, CFU-GM, CFU-Mix, BFU-E, and CFU-E in mice for 3 consecutive days were studied, and its therapeutic effect on leukopenia in mice irradiated with low dose was studied. Specific steps are as follows:
[0067] (1) Experimental materials and methods
[0068] 1. Experimental materials
[0069] BALB / C mice, 5-6 weeks old, weighing 16-20g. Experimental Animal Quality Certificate No. SCXK-(Army) 2007-004, Animal Experimental Facility License No. SYXK-(Army) 2007-004.
[0070] 2. Experimental method
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