Berberine hydrochloride oral pill dried gel as well as preparation method and applications thereof

A technology of berberine hydrochloride and xerogel, which is applied in the field of berberine hydrochloride oral pellet xerogel and its preparation, can solve the problems of inability to improve children's medication compliance, poor fluidity of drug tablets, and difficulty in masking bitter taste, etc. Achieve the effects of reducing gastrointestinal irritation, less adverse reactions, and reducing the number of medications
CN106511260AActive Publication Date: 2017-03-22黑龙江童医生儿童生物制药有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
黑龙江童医生儿童生物制药有限公司
Publication Date
2017-03-22

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Abstract

The invention provides berberine hydrochloride oral pill dried gel as well as a preparation method and applications of the berberine hydrochloride oral pill dried gel. According to the berberine hydrochloride oral pill dried gel as well as the preparation method and the applications of the berberine hydrochloride oral pill dried gel, firstly, the applications of berberine hydrochloride in preparing the medicines for treating heart diseases are defined, and secondly, the condition that the berberine hydrochloride oral pill dried gel comprises berberine hydrochloride pills uniformly distributed in gel matrix is defined, and the gel matrix comprises a gel forming agent, a curing agent, a corrigent, an aromatic, a preservative and a pH regulator. The berberine hydrochloride provided by the invention can be used for preparing the medicines for treating heart diseases, the treatment effects are obvious, and the side effects can be effectively reduced; for the berberine hydrochloride, through the pill coating technology, the stability of the medicine is improved, the bad smell of the medicine is masked, and the side effects are reduced; meanwhile, after the pill is added into the gel matrix, the slow release effect can be effectively achieved, so that the medicine taking times is reduced, the irritation to the gastrointestinal tract is reduced, the mouthfeel of the preparation is completely improved, the fearful mental state generated when children patients take the medicine is overcome, and the compliance is improved.
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Description

technical field

[0001] The invention relates to the technical field of pharmacy, in particular to a dry gel of berberine hydrochloride oral pellets and a preparation method and application thereof. Background technique

[0002] At present, heart disease has become one of the diseases with the highest morbidity, mortality and disability, seriously affecting human life and health. Statistics show that 17 million people die from heart disease every year in the world, and one out of every three deaths due to disease is a heart disease patient. Heart disease has become the number one killer of human health.

[0003] At present, the drugs for treating heart diseases mainly include cardiotonic drugs, antiarrhythmic drugs and antianginal drugs. These three types of drugs are basically chemical drugs, and various adverse reactions may occur if they are used improperly or for a long time. For example, digitalis is the representative of cardiotonic drugs, and loss of appetite, nausea,...

Claims

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