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A method of composting medicinal residues

A composting method and a technology of medicinal dregs, which are applied in the direction of nitrogen fertilizer, fertilization equipment, organic fertilizer, etc., can solve the problems of no treatment method and legal storage yard, odor, irritating taste of solvents, etc., and achieve the effect of harmless treatment

Inactive Publication Date: 2019-05-17
INST OF AGRI RESOURCES & REGIONAL PLANNING CHINESE ACADEMY OF AGRI SCI +1
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

However, lovastatin is a fermented product, and waste residue is produced during the production process, of which the fermented residue is about 700t per year, containing unconsumed protein, fat, bacterial corpses, cellulose and other substances, almost tasteless, solid, light gray, water soluble After that, it becomes a paste; if the fermentation residue is not transported and disposed of in time, it will stink after being piled up for 1-2 days
Lovastatin refining residue is mainly filter aid and a small amount of unconsumed protein and fat. It is the filter residue after separation and filtration and extracted with solvent. It has a pungent solvent taste. About 350t of lovastatin refining residue is produced every year and mixed with coal for use The boiler is incinerated, but there is still no further treatment method and legal stockpile; therefore, the pharmaceutical company that produces lovastatin has a greater impact on the surrounding environment and the lives of residents

Method used

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  • A method of composting medicinal residues
  • A method of composting medicinal residues
  • A method of composting medicinal residues

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0043] Example 1: Changes in antibiotic content during composting of gentamicin dregs and lovastatin dregs

[0044] The gentamicin dregs, lovastatin dregs and urea were divided into three piles according to the mass ratio of 15:1:0.1400, 10:1:0.1009 and 5:1:0.0618 for composting, respectively marked as pile 1, pile Body 2, heap body 3, the weight of each heap body is 100kg; Promptly weigh gentamicin dregs and lovastatin dregs to mix, then sprinkle urea and FZC3 Aspergillus terreus (Aspergillus terreus addition amount) while stirring 2.5%, v / w), mix the above four, so that the final water content is 60-65%, C / N is 40:1; check the temperature of the pile, when the temperature of the pile rises to 50°C, start turning Heap, turning once every 2 days, when the temperature of the heap body drops below 50 ℃, turning once every 4 days, the number of days of composting is 21 days. The sampling time is 3d, 7d, 11d, 15d, 21d respectively. The sampling method is to take the upper, middle ...

Embodiment 2

[0048] Example 2: Effects of Different Exogenous Nitrogen Sources on the pH Value of Compost Fertilizers

[0049] Those skilled in the art know that the pH value of a high-quality organic fertilizer should be between 5.5 and 8.5, especially not greater than 8.5, otherwise the soil will be alkalized.

[0050] In this experiment, gentamicin dregs, lovastatin dregs, and exogenous nitrogen sources (select urea, potassium nitrate, and potassium nitrate fertilizer in turn) were composted according to the mass ratio of 15:1:0.1400, and correspondingly marked as compost Body 1, pile 4, and pile 5, the total weight of each pile is 100kg; that is, first weigh the gentamicin dregs and lovastatin dregs and mix them, and then sprinkle the selected exogenous Nitrogen source and FZC3 Aspergillus terreus (the addition of Aspergillus terreus is 2.5%, v / w), mix the above four to keep the final water content at 60-65%, and adjust the C / N to 40:1, 30:1 and 50:1; detect the temperature of the pil...

Embodiment 3

[0053] Embodiment 3: along with the change of organic matter content in the heap body of composting days:

[0054] The content of organic matter in organic fertilizer is an important parameter to measure the quality of the organic fertilizer. Generally speaking, the mass fraction of organic matter in a good organic fertilizer (calculated on a dry basis) should be ≥ 45%; if it is converted into a wet fertilizer ( The humidity in the compost is 45-60%), and its organic matter content is better than or equal to 25%.

[0055] By sampling pile 1, pile 4, and pile 5, the sampling time is 1d, 3d, 7d, 11d, 15d, and 21d respectively. The sampling method is to collect the upper, middle and lower samples of pile 1, pile 4 and pile 5 respectively, mix them evenly, put them in a ziplock bag, store them at 4°C, and measure the mass percentage of organic matter content in each sample. In this experiment, the determination method of organic matter in organic fertilizer NY525-2012 was used. ...

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Abstract

The invention discloses a medicine residue composting method. The medicine residue composting method comprises the steps that gentamicin residues and lovastatin residues are mixed according to the mass ratio of 15-1:1, aspergillus terreus FZC3 is added in the mixing process, the preservation number is CGMCC12072, and meanwhile an exogenous nitrogen source is added to regulate the C / N ratio in residue fertilizers; all the components are mixed evenly, and the moisture content of the final mixed pile is 60-65%; and the temperature of the pile is detected, when the temperature of the pile is increased to 50 DEG C, the pile starts to be turned and is turned once every two days, and when the temperature of the pile is decreased to below 50 DEG C, the pile is turned once every four days, and the composting duration is smaller than or equal to 21 days. According to the composting method, the removal rate of antibiotic left in the gentamicin residues is 95% or over, and innocent treatment of the gentamicin residues is achieved; in addition, as for organic fertilizers obtained through the composting method, the humification coefficient reaches 30% or over, detection of all indexes prove that all the indexes meet the national industry standards, and the organic fertilizers are high-quality fertilizers with a good fertilizer effect and can be applied to various kinds of soil and crops.

Description

technical field [0001] The invention belongs to the technical field of bioengineering, in particular to a method for composting medicinal dregs. Background technique [0002] The proper disposal of drug residues in pharmaceutical companies has always been one of the problems that companies must face. For traditional Chinese medicine pharmaceutical companies, since the main components of the extracted drug residues of traditional Chinese medicine are the branches and leaves of Chinese herbal medicines, which basically do not contain toxic components that are difficult to degrade, organic The method of fertilizer is processed; it will not cause serious pollution to the environment. The principle of composting traditional Chinese medicine residues with organic fertilizers is similar to the composting of crop straws, and is relatively easy to operate and easy to think about. However, for some companies producing western medicines, the proper disposal of drug residues is even m...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C05F17/00C05G1/00
CPCC05B17/00C05C9/00C05F17/00C05F5/006C05F5/008C05F11/08C05C5/02Y02W30/40
Inventor 李兆君刘元望齐红革葛祥斌郝金海张卫胡海燕冯瑶杜德维章程王莉莉付丽莉张家俊
Owner INST OF AGRI RESOURCES & REGIONAL PLANNING CHINESE ACADEMY OF AGRI SCI