Compound preparation for treating influenza and preparation method of compound preparation

A technology of influenza and compound preparations, applied in the field of medicine, can solve the problems of different pharmacokinetic properties, difficult to achieve therapeutic effect, and easy to cause side effects, etc., to achieve improved bioavailability, easy industrial production, and small side effects Effect

Active Publication Date: 2017-05-31
HENGHE PHARMA GUIZHOU
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] In the research on the treatment of influenza, under normal circumstances, Western medicine mainly uses antiviral western medicines. Although they have a quick effect in the early stage of the disease, they treat the symptoms but not the root cause; antiviral drugs also have certain inhibitory effects on normal human cells. effect, so it is easy to cause side effects
What's more, it will aggravate the patient's condition
Secondly, when combining drugs to treat influenza, the pharmacokinetic properties of the single drugs are different, so it is not easy for common dosage forms to achieve the desired therapeutic effect in patients.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0021] The present invention also provides a preparation method for the compound preparation for treating influenza, comprising the following steps:

[0022] Material preparation and pretreatment steps: Weigh the first component, the second component, the third component and the fourth component respectively according to the drug formula, in parts by weight, the first component includes acetaminophen 60-100 The second component includes 100-140 parts of Platycodon grandiflora, 100-145 parts of calcium carbonate, and 160-200 parts of buffalo horn; the third component includes 80-140 parts of light tempeh, 160-250 parts of honeysuckle, 100-200 parts of burdock 140 parts, 160-220 parts of forsythia, 60-90 parts of light bamboo leaves, 160-240 parts of reed root, and 60-120 parts of coix seed; the fourth component includes 60-100 parts of Nepeta ear and 0.35-1 parts; the first component and the second component were pulverized into the first powder and the second powder with a par...

Embodiment 1

[0032] This embodiment provides a compound preparation for treating influenza and a preparation method thereof. The compound preparation is a granule. The compound preparation includes the first component, the second component, the third component and the fourth component. The first component is 60g of acetaminophen; the second component includes 100g of bellflower, 100g of calcium carbonate and 160g of buffalo horn; the third component includes 80g of light tempeh, 160g of honeysuckle, 100g of burdock, 160g of forsythia, and 60g of light bamboo leaves 160g reed rhizome and 60g coix seed; the fourth component includes 60g nepeta panicle and 0.35g menthol; excipients include starch, magnesium stearate, microcrystalline cellulose, lactose and sodium hydroxypropyl methylcellulose.

[0033] The preparation method of this compound preparation:

[0034] Material preparation and pretreatment steps: Weigh the first component, the second component, the third component and the fourth c...

Embodiment 2

[0040] This example provides a compound preparation for treating influenza and a preparation method thereof. The compound preparation is a capsule. The compound preparation includes the first component, the second component, the third component and the fourth component. The first component is 72g of acetaminophen; the second component includes 120g of bellflower, 133g of calcium carbonate and 180g of buffalo horn; the third component includes 100g of light tempeh, 200g of honeysuckle, 120g of burdock, 200g of forsythia, and 80g of light bamboo leaves , reed rhizome 200g and coix seed 80g; the fourth component includes nepeta panicle 80g and menthol 0.5g; excipients include starch, magnesium stearate, microcrystalline cellulose, lactose and sodium hydroxypropyl methylcellulose.

[0041] The preparation method of this compound preparation:

[0042] Material preparation and pretreatment steps: Weigh the first component, the second component, the third component and the fourth co...

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Abstract

The invention provides a compound preparation for treating influenza and a preparation method of the compound preparation. According to the compound preparation, first medical powder, second medical powder, a medicinal material dry extract and medicinal material essential oil are mixed to prepare pellets, and the pellets are prepared into granules, capsules or tablets; the first medical powder and the second medical powder are respectively prepared by grinding and mixing a first component and a second component; the medicinal material dry extract is prepared by extracting and concentrating a third component; the medicinal material essential oil is prepared from a fourth component; the first component includes acetaminophen; the second component includes platycodon grandiflorum, calcium carbonate and cornu bubali; the third component includes fermented soybean, honeysuckle, burdock, fructus forsythia, lophatherum gracile, rhizoma phragmitis and semen coicis; the fourth component includes schizonepeta spike and menthol. The compound preparation is prepared into the pellets, so that the stability of the compound preparation is improved, the toxic and side effects are reduced, and meanwhile, a controlled release effect is achieved; secondly, the outer surfaces of Chinese herbal medicinal ingredients are packaged by acetaminophen, the effects of cooling and easing pain can be rapidly achieved, and the bioavailability is improved.

Description

technical field [0001] The invention relates to the technical field of medicines, and in particular to a compound preparation for treating influenza and a preparation method thereof. Background technique [0002] Influenza (abbreviated as influenza) is an acute respiratory infectious disease caused by influenza virus, with high susceptibility among the population, outbreaks and high incidence of complications. Its clinical manifestations include fever, headache, myalgia, fatigue, nasal congestion, throat congestion, cough, and gastrointestinal discomfort. Influenza can aggravate the underlying disease (cardiopulmonary disease) and can cause secondary bacterial pneumonia or primary influenza viral pneumonia. The elderly and those suffering from various chronic diseases or weak constitutions are prone to severe complications after influenza, and the case fatality rate is high. [0003] Traditional Chinese medicine believes that a common cold is commonly known as a cold. It i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61K9/16A61P31/16A61P11/00A61K31/045A61K31/167A61K33/10A61K35/32
CPCA61K9/1652A61K9/167A61K31/045A61K31/167A61K33/10A61K35/32A61K36/28A61K36/346A61K36/355A61K36/48A61K36/538A61K36/634A61K36/899A61K36/8994A61K2300/00
Inventor 黄静
Owner HENGHE PHARMA GUIZHOU
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