The invention relates to a medicine combination for promoting blood circulation and removing blood stasis, which is characterized by comprising the following raw materials of Chinese herbal medicines in ratio by weight: group A comprises 14 raw materials of saffron, safflower, angelica, akebiaquinata, sevenlobed yamn rhizome, gentiana macrophylla pall, radix angelicae pubescentis, artemisia indica, bamboo leaves, tea leaves, erythrina indica lam, cortex acanthopanacis, cortex cinnamomi and panax pseudo-ginseng, 2-4 parts for each; group B comprises 6 raw materials of plantain seed, semen boitae, lotus seed, Chinese wolfberry fruit, red bean and longan, 1-3 parts for each; group C comprises 4 raw materials of Shenguisan, cartialgenous powder, antelope horn powder and pearl powder, 0.5-1.5 parts for each; and group D comprises 3 raw materials of frankincense, myrrh and amber, 0.5-1.5 parts for each. The medicine combination in the invention has the effects of relieving fever and pain, stimulating blood circulation, causing the muscles and jointing to relax, removing blood stasis, and arresting blood and dysentery and the like; can cure aches caused by scapulohumeral periarthritis, arthritis, convulsion, fatigues and the like; and sore pain and dysentery caused by injuries from falls. The medicine combination has obvious effect by clinical trial use.