The invention discloses roxburgh rose fruit wine and a making process thereof. The roxburgh rose fruit wine is prepared from roxburgh rose through the steps of raw material pretreatment, enzymolysis, blending, yeast activation, fermentation, mixing, ageing, clarification, filtering, filling, sterilization and the like. According to the making process, the roxburgh rose is diced and is put into high-alcohol-concentration white wine to be soaked, so that the loss of nutrient substances is avoided; the soaked roxburgh rose is pulped and is subjected to compound enzyme treatment, so that more nutrient substances can be separated from the roxburgh rose, and the utilization efficiency of the roxburgh rose is improved; by carrying out clarification by virtue of a compound clarifying agent after ageing, the finished roxburgh rose fruit wine has stable color and soft taste, is transparent and further has multiple health efficacies of promoting digestion, tonifying spleen, converging and stopping diarrhea, clearing summer-heat, enhancing physique, and the like.