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Chinese medicine oral preparaton for treating urinary system infestation and its preparation method

A technology for urinary tract infection and oral preparations, which is applied in the field of preparation of pharmaceuticals, which can solve the problems of not being able to fully exert its therapeutic effect, difficult acceptance by diabetic patients, and inconvenient transportation and carrying, and achieve easy transportation, storage and carrying, strong mechanical properties, and moisture resistance good performance

Inactive Publication Date: 2005-01-05
陈玲玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are certain defects in the above-mentioned preparation process. For example, all the medicines in the prescription are mixed and decocted together for extraction, and the main active ingredients contained in Phellodendron Phellodendri, Angelica dahurica, Schisandra chinensis, etc. cannot be effectively extracted, so the therapeutic effect of the formula cannot be fully utilized. effect
In addition, judging from its usage and dosage and the situation in the actual clinical application process, because it is a granule, 5 times the amount of excipients—sucrose and dextrin—is added in the preparation process, so the dosage is large and transportation is difficult. Inconvenient, etc., while containing a lot of sugar, diabetic patients are not easy to accept, which limits the wide use of this variety in clinical practice

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] (1) Take 100g of Angelica dahurica and 100g of Schisandra chinensis, mix them, add 8 times the amount of 80% ethanol, and reflux extraction twice, each time for 1.5h. Combine ethanol extracts, recover ethanol under reduced pressure, concentrate into a thick paste, dry at low temperature, crush into fine powder, and set aside;

[0037] (2) Take 120g of Cortex Phellodendri and add 10 times the amount of water to soak for 1 hour, decoct twice for 1.5 hours each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.05-1.08 (measured at 60°C), add ethanol to the alcohol When the concentration reaches 50%, stir, stand still for 24 hours, filter, wash the residue with 50% ethanol until it is nearly colorless, combine the filtrate and lotion, recover ethanol under reduced pressure, concentrate to a thick paste, dry in low temperature vacuum, crush into fine powder, and set aside;

[0038] (3) Take 120g of Bupleurum, 100g of zhu, 100g...

Embodiment 2

[0041] (1) Take 400g of Angelica dahurica and 400g of Schisandra chinensis, mix them, add 10 times the amount of 70% ethanol, and reflux extraction for 3 times, 1 hour each time. Combine ethanol extracts, recover ethanol under reduced pressure, concentrate into a thick paste, dry at low temperature, crush into fine powder, and set aside;

[0042] (2) Take 480g Cortex Phellodendri and add 12 times the amount of water to soak for 3 hours, decoct twice for 2 hours each time, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.12 (measured at 60°C), add ethanol until the alcohol concentration reaches 60 %, stirred, stood still for 18 hours, filtered, the residue was washed with 60% ethanol until nearly colorless, the filtrate and lotion were combined, the ethanol was recovered under reduced pressure, concentrated to a thick paste, dried in vacuum at low temperature, crushed into fine powder, and set aside;

[0043] (3) Take 480g of Bupleurum...

Embodiment 3

[0046] (1) Take 110 g of Angelica dahurica and 90 g of Schisandra chinensis, mix them, add 7 times the amount of 60% ethanol, and reflux extraction twice, each time for 2.5 hours. Combine ethanol extracts, recover ethanol under reduced pressure, concentrate into a thick paste, dry at low temperature, crush into fine powder, and set aside;

[0047] (2) Take 130g Cortex Phellodendri and add 10 times the amount of water to soak for 3 hours, decoct 4 times, each time for 1 hour, filter, combine the filtrate, concentrate under reduced pressure to a relative density of 1.07 (measured at 60°C), add ethanol until the alcohol concentration reaches 50 %, stir, stand for 22 hours, filter, wash the residue with 50% ethanol until it is nearly colorless, combine the filtrate and lotion, recover ethanol under reduced pressure, concentrate to a thick paste, dry in vacuum at low temperature, crush into fine powder, and set aside;

[0048] (3) Take 110g of Bupleurum bupleuri, 110g of zhu, 90g ...

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Abstract

A Chinese medicine in the form of capsule or tablet for treating the infection of urinary system is prepared from 9 Chinese-medicinal materials including bupleurum root, common knot-grass, phellodendron bark, schisandra fruit, etc through extracting, concentrating, drying, mixing with additive, and loading in capsules or tabletting.

Description

Technical field [0001] The invention belongs to the technical field of preparation of medicines, and in particular relates to a Chinese patent medicine oral preparation for treating urinary tract infection and a preparation method thereof. Background technique [0002] Urinary tract infection refers to inflammation of the urinary system caused by non-specific bacterial infections of the upper and lower urinary tracts, including pyelonephritis, cystitis, and urethritis. It is now called a urinary tract infection. Epidemiological data of urinary tract infection show that the disease is mostly female, the incidence rate of unmarried girls is 2%, and the incidence rate of married women increases to 5%, which is related to sex life. The incidence of urinary tract infection in pregnant women is about 7%. Urinary tract infection rarely occurs in men, and it occurs more frequently after the age of 50 due to enlarged prostate. UTIs can occur in up to 10% of older women and men. F...

Claims

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Application Information

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IPC IPC(8): A61K9/20A61K9/48A61P13/02
Inventor 陈玲玲
Owner 陈玲玲
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