Sugar-free almond perilla anti-cough granules and preparation method thereof

A granule and sugar-free technology, applied in the field of medicine, can solve the problems of inconvenient production, storage and transportation, restriction of clinical application, easy moisture absorption and agglomeration, etc. little effect

Inactive Publication Date: 2010-08-25
沈阳神龙药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Cold is a common and frequently-occurring disease, and there are many kinds of medicines for it. Western medicines are mainly antibiotics, antipyretic and analgesic medicines and antiviral medicines. The nature of the medicine, and excessive use can also cause toxic reactions, and the use of traditional Chinese medicine to treat such diseases can avoid the shortcomings of the above-mentioned western medicine
[0003] Xingsu Zhike Granules is a classic Chinese patent medicine

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0023] Example 1

[0024] A sugar-free type Xingsu cough relieving granule is prepared from 63g bitter almonds, 47g tangerine peel, 63g perilla leaves, 47g platycodons, 63g cephalopectin, 16g licorice, 200g dextrin, 200g starch and 2g stevia.

[0025] A preparation method of sugar-free Xingsu cough relieving granules is: take 63g of bitter almonds, mash them, soak in warm water for 24 hours, heat and distill, and introduce the distillate into a container containing 90% ethanol. When the amount of distillate reaches 50ml, Stop the distillation and re-distill. Collect about 17ml of the re-distilled liquid. Take the re-distilled liquid to determine the content of amygdalin, and dilute to 51mg of amygdalin per 1ml for use; take 63g of perilla leaves, 63g of Qianhu and 42g of tangerine peel Distill and extract the volatile oil, and save the distilled aqueous solution; Take 37g of Platycodon grandiflorum and 16g of licorice, mix with the above-mentioned bitter almond, perilla leaf, Peuce...

Example Embodiment

[0026] Example 2

[0027] A sugar-free Xingsu cough relieving granule is prepared from 63g bitter almonds, 47g tangerine peel, 63g perilla leaves, 47g platycodons, 63g cephalopectin, 16g licorice, 200g starch, 120g microcrystalline cellulose and 4g xylitol.

[0028] A preparation method of sugar-free Xingsu cough relieving granules is: take 63g of bitter almonds, mash them, soak in warm water for 24 hours, heat and distill, and introduce the distillate into a container containing 90% ethanol. When the amount of distillate reaches 50ml, Stop the distillation and re-distill, collect about 17ml of the re-distilled liquid, take the re-distilled liquid to determine the content of amygdalin, and dilute to 51mg of amygdalin per 1ml for later use; take 63g of perilla leaf, 63g of Qianhu and 47g of tangerine peel Distill, extract the volatile oil, and store the distilled aqueous solution in a separate container; take 47g of Platycodon grandiflorum and 16g of licorice, mix with the above-men...

Example Embodiment

[0029] Example 3

[0030] A sugar-free Xingsu cough relieving granule is prepared from 63g bitter almonds, 47g tangerine peel, 63g perilla leaves, 47g platycodons, 63g cephalopectin, 16g licorice, 350g starch, 150g lactose and 1.5g aspartame.

[0031] A preparation method of sugar-free Xingsu cough relieving granules: Take 63g of bitter almonds, mash them, soak in warm water for 24 hours, heat and distill, and introduce the distillate into a container containing 90% ethanol. When the amount of distillate reaches 50ml, stop Distill, re-distill, collect about 17ml of the re-distilled liquid, take the re-distilled liquid to determine the content of amygdalin, and dilute to 51mg of amygdalin per 1ml for later use; take 63g of perilla leaves, 63g of Qianhu and 47g of dried tangerine peel for distillation , Extract the volatile oil, and save the distilled aqueous solution in another container; take 47g of Platycodon grandiflorum, 16g of licorice and the above-mentioned bitter almond, per...

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Abstract

The invention discloses sugar-free almond perilla anti-cough granules, which are characterized in that: the almond perilla anti-cough granules are prepared from the following components: 63g of bitter almond kernel, 47g of tangerine peel, 63g of perilla leaf, 47g of platycodon root, 63g of whiteflower hogfennel root, 16g of liquorice, 100 to 950g of diluent, 0 to 100g of wetting agent or binding agent, 0 to 10g of flavoring agent and 0 to 50g of disintegrating agent. The sugar-free almond perilla anti-cough granules have the advantages that: the sugar-free almond perilla anti-cough granules do not contain sucrose, so the sugar-free almond perilla anti-cough granules cannot cause obesity after long-term use; the sugar-free almond perilla anti-cough granules contain a sweetening agent and have good mouthfeel; the administrative dosage is low, the use is convenient and the patient compliance is good; the product quality is stable, and the sugar-free almond perilla anti-cough granules difficultly absorb moisture and cake, and have long quality guarantee period; the curative effect is definite and the adverse effect is less; the preparation process is simple and the sugar-free almond perilla anti-cough granules are easy for industrial production; and the sugar-free almond perilla anti-cough granules have wide application range, and the patient avoiding sugar such as diabetics can use the sugar-free almond perilla anti-cough granules; and the like.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a sugar-free Xingsu cough granule and a preparation method thereof. technical background [0002] Cold is a common and frequently-occurring disease, and there are many kinds of medicines for treating it. Western medicine mainly uses antibiotics, antipyretic and analgesic medicines, and antiviral medicines. Although western medicines have quick effects, they are prone to resistance The nature of the medicine, and excessive use can also cause toxic reactions, and the use of traditional Chinese medicine to treat such diseases can avoid the shortcomings of the above-mentioned western medicine. [0003] Xingsu Zhike Granules is a classic Chinese patent medicine, which has the effects of dispersing lung qi, dispersing wind and cold, antitussive and expectorant, and has a good effect on cold and cold, and cough with adverse qi. However, the preparation contains a lot of sucrose, which is...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/16A61K47/38A61K47/36A61K47/32A61P11/14
Inventor 王威
Owner 沈阳神龙药业有限公司
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