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Toothpaste containing eugenol and preparation method of toothpaste

A technology of eugenol and toothpaste, which is applied in the field of eugenol-containing toothpaste and its preparation, can solve the problems of endocrine system dysfunction, enamel demineralization, dissolution, dental fluorosis, etc., achieve significant gum bleeding, prevent dental caries, and achieve the effect significant effect

Inactive Publication Date: 2017-08-11
泰州优克生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Dental caries (Dental Caries) is a disease of chronic progressive destruction of dental hard tissue under the influence of bacteria-based multi-factors, and is the most common oral disease; dental plaque is the process of dental caries. Indispensable micro-ecological environment; the acidic metabolites produced by bacteria metabolizing carbohydrates in plaque can lead to demineralization and dissolution of tooth enamel, and then form caries; including periodontitis, toothache, tooth sensitivity, etc., these oral diseases have always been troubled It affects people's lives; the World Health Organization has listed it as the three major diseases that endanger human health along with cancer and cardiovascular disease; Although the ingredients have a certain effect of inhibiting harmful bacteria in the oral cavity, preventing periodontitis, anti-inflammatory and analgesic; in addition, there are many fluoride-containing toothpastes on the market, which are relatively common, and long-term use of fluoride-containing toothpaste will cause dental fluorosis. Intake of high doses of fluoride may lead to problems such as cancer, neurological diseases, and endocrine system dysfunction; therefore, providing a pharmaceutical toothpaste and a preparation method for treating oral diseases with a more significant analgesic effect has become an important topic in this field. One of the problems that technicians are eager to solve

Method used

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  • Toothpaste containing eugenol and preparation method of toothpaste
  • Toothpaste containing eugenol and preparation method of toothpaste
  • Toothpaste containing eugenol and preparation method of toothpaste

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A toothpaste containing eugenol, its raw material formula by weight percentage is: 0.5-2.0% eugenol, 20-60% sorbitol, 5-15% polyethylene glycol, 0.5-1.5% carboxymethyl cellulose, hydrated Silica 12-25%, glycerin 12-25%, hydroxyethyl cellulose 0.2-1.0%, saccharin 0.05-0.5%, sodium lauryl sulfate 0.5-5%, water 5-12%, probiotic powder 0.5-2 %, whey protein 0.5-2%, methylisothiazolinone 0.005-0.02%.

[0030] The concrete preparation steps of drug toothpaste of the present invention are as follows:

[0031] 1) Sub-measure feeding, glue making, paste kneading, grinding, vacuum degassing, aging, etc.; two-step production process is adopted, and the above steps are completed in the same paste making pot.

[0032] 2) Dissolve spices, active additives, stabilizers, and saccharin in a pre-dissolving pot with pure water until uniform, add to the paste pot, and then add the liquid materials in the liquid material storage tank to the paste pot respectively, and then add powder materi...

Embodiment 2

[0034] A toothpaste containing eugenol, its raw material formula by weight percentage is: eugenol 0.7-1.5%, sorbitol 30-50%, polyethylene glycol 8-12%, carboxymethyl cellulose 0.8-1.2%, hydrated Silica 15-20%, glycerin 15-20%, hydroxyethyl cellulose 0.3-0.8%, saccharin 0.1-0.3%, sodium lauryl sulfate 1-3.5%, water 6.5-10%, probiotic powder 0.6-1.5 %, whey protein 0.8-1.5%, methylisothiazolinone 0.008-0.015%.

[0035] The preparation method is the same as in Example 1.

Embodiment 3

[0037] A toothpaste containing eugenol, its raw material formula by weight percentage is: eugenol 0.9-1.25%, sorbitol 35-45%, polyethylene glycol 9-11%, carboxymethyl cellulose 0.95-1.1%, hydration Silica 16-19%, glycerin 17-19%, hydroxyethyl cellulose 0.4-0.7%, saccharin 0.15-0.25%, sodium lauryl sulfate 1.5-2.5%, water 7.5-8.5%, probiotic powder 0.8-1.2 %, whey protein 0.9-1.2%, methylisothiazolinone 0.009-0.012%.

[0038] The preparation method is the same as in Example 1.

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Abstract

The invention provides toothpaste containing eugenol and a preparation method of the toothpaste, relating to oral care products. The toothpaste comprises eugenol, sorbitol, polyethylene glycol, carboxymethyl cellulose, hydrated silica, glycerol, hydroxyethyl cellulose, saccharin, sodium lauryl sulfate, water, probiotic powder, whey protein and methylisothiazolinone. The toothpaste containing eugenol has the efficacies of reliving heat and easing pain, resisting inflammation, and realizing anaesthetizing, also has the efficacies of resisting bacteria, resisting fungi, resisting oxidation, resisting cancer, and the like, has the extremely high treatment effects for gingivitis and gingival bleeding, and has the obvious analgesic effect for toothache; after eugenol is added into the toothpaste, the product can be widely applied to analgesia, anesthetics, inflammation resistance and analgesia of the dental department, so that the effects in treating toothache, and resisting gingivitis, gingival bleeding and pain are obvious; meanwhile, compared with the fluoride-containing toothpaste, due to eugenol, the toothpaste containing eugenol has the advantages that the defects of fluoride-containing toothpaste can be overcome, and decayed tooth can be effectively prevented.

Description

technical field [0001] The invention relates to an oral care product, in particular to a toothpaste containing eugenol and a preparation method thereof. Background technique [0002] Dental caries (Dental Caries) is a disease of chronic progressive destruction of dental hard tissue under the influence of bacteria-based multi-factors, and is the most common oral disease; dental plaque is the process of dental caries. Indispensable micro-ecological environment; the acidic metabolites produced by bacteria metabolizing carbohydrates in plaque can lead to demineralization and dissolution of tooth enamel, and then form caries; including periodontitis, toothache, tooth sensitivity, etc., these oral diseases have always been troubled It affects people's lives; the World Health Organization has listed it as the three major diseases that endanger human health along with cancer and cardiovascular disease; Although the ingredients have a certain effect of inhibiting harmful bacteria in...

Claims

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Application Information

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IPC IPC(8): A61K8/34A61Q11/00A61Q17/00A61K31/085A61P1/02A61P29/00A61P23/00A61P31/04A61P31/02A61P31/10A61P39/06A61P35/00A61P7/04
CPCA61K8/347A61K31/085A61Q11/00A61Q17/005
Inventor 唐正尧唐静
Owner 泰州优克生物科技有限公司
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